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Published on: 7/9/2025

What might cause one nipple to be more sensitive than the other?

Uneven nipple sensitivity may be caused by friction, hormonal changes, breastfeeding habits, skin irritation, or underlying conditions affecting just one side.

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Explanation

It's not uncommon to notice that one nipple feels more sensitive than the other. Possible causes include:

Friction or clothing irritation: One nipple may rub more against clothing, especially during exercise or while sleeping on one side. Hormonal fluctuations: Hormones may affect each breast differently, especially around your menstrual cycle, pregnancy, or breastfeeding. Breastfeeding factors: If a baby favors one breast or latches differently on each side, it can lead to uneven nipple soreness or sensitivity. Skin conditions: Eczema, dermatitis, or allergic reactions may affect one nipple more than the other. Infections or inflammation: Conditions like mastitis or clogged ducts can cause localized tenderness or sensitivity. Benign lumps or cysts: These may sometimes cause localized discomfort or altered sensitivity.

If sensitivity persists, worsens, or is accompanied by discharge, swelling, or a lump, it’s important to see a healthcare provider to rule out more serious causes.

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