What Are the Possible Causes of Upper Left Quadrant Abdominal Pain?

Pain in the left upper quadrant of the abdomen most commonly is due to stomach issues such as gastritis (stomach inflammation) or ulcers. Common symptoms of gastritis include burning pain, nausea, and loss of appetite, while stomach ulcers often cause a gnawing or sharp pain that may be worse when the stomach is empty. In some cases, these conditions may be triggered by H. pylori infection, excessive use of NSAIDs, or chronic stress. That being said, several other organs are in this area and can trigger pain. Splenic problems like enlargement or rupture (which typically occurs after trauma) can cause pain in this area. Issues with the colon near the splenic flexure (located in the left upper abdomen) or even musculoskeletal strain also may cause left upper abdominal pain. Additionally, since the tail of the pancreas sits in this region, conditions like pancreatitis may cause upper left abdominal discomfort. Less commonly, heart issues may manifest with pain in the left upper abdomen rather than the chest. Because the underlying cause of the pain depends on accompanying symptoms and clinical findings, you should consult a healthcare provider for pain that is severe or persistent. The provider can take a complete medical history, conduct a physical examination, and order appropriate tests to make an accurate diagnosis and develop a treatment plan.