Published on: 4/7/2025
Upper right quadrant pain during pregnancy is not common and should be evaluated by a doctor, as it may indicate an underlying condition.
While some aches and pains are normal during pregnancy due to bodily changes, upper right abdominal pain is less common. Sharp or intense pain in the upper right side of your abdomen may indicate gallbladder or liver problems. Various conditions can develop during pregnancy as your body undergoes changes to support your growing baby. For example, gallstones may develop during pregnancy because of changes in hormone levels and increased cholesterol production. These hormonal shifts can cause bile to become more concentrated and crystallize into stones. Additionally, the growing uterus can put pressure on the gallbladder, potentially affecting how it functions. In some cases, liver-related issues may also occur during pregnancy. Conditions like HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets) or preeclampsia can affect liver function and cause pain in the upper right quadrant. These conditions require immediate medical attention as they can pose serious risks to both mother and pregnancy. Since these conditions require medical attention, contact your doctor if you experience this type of pain—particularly if it's severe, persistent, or accompanied by symptoms like fever, nausea, or changes in your daily activities. Your healthcare provider will evaluate your symptoms and determine whether tests are needed to ensure the well-being of both you and your pregnancy.
(References)
Zachariah SK, Fenn M, Jacob K, Arthungal SA, Zachariah SA. Management of acute abdomen in pregnancy: current perspectives. Int J Womens Health. 2019 Feb 8;11:119-134. doi: 10.2147/IJWH.S151501. PMID: 30804686; PMCID: PMC6371947.
Aptilon Duque G, Oladipo AF, Lotfollahzadeh S. Appendicitis in Pregnancy. [Updated 2023 Nov 17]. In: StatPearls [Internet].
Masselli G, Bonito G, Gigli S, Ricci P. Imaging of Acute Abdominopelvic Pain in Pregnancy and Puerperium-Part II: Non-Obstetric Complications. Diagnostics (Basel). 2023 Sep 11;13(18):2909. doi: 10.3390/diagnostics13182909. PMID: 37761275; PMCID: PMC10528125.
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