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Published on: 4/7/2025

What Are the Possible Causes of Upper Right Quadrant Abdominal Pain?

Upper right quadrant pain can be caused by issues with the gallbladder, liver, or nearby organs, such as gallstones, cholecystitis, or liver inflammation.

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Explanation

Pain in the upper right side of your belly can have many causes. One common cause is gallbladder problems. In many cases, gallstones (small stones that form in the gallbladder) or cholecystitis (inflammation of the gallbladder) can lead to severe pain in this area, especially after eating fatty meals. The liver, which is also on the right side, can be another source of pain if it is inflamed, as in hepatitis or from other conditions. Sometimes the bile ducts, which carry bile from the liver and gallbladder, can be blocked or inflamed. Other nearby structures like the colon, right kidney, or even parts of the lung may also cause pain that feels like it is coming from the upper right abdomen. Ultrasound is often the first test used because it is good at showing problems with the gallbladder and liver. It is important to see a healthcare provider for a proper evaluation to determine the exact cause and decide on the best treatment.

(References)

  • Kingham JG, Dawson AM. Origin of chronic right upper quadrant pain. Gut. 1985 Aug;26(8):783-8. doi: 10.1136/gut.26.8.783. PMID: 4018643; PMCID: PMC1432792.

  • Rathgaber S, Rex DK. Right upper quadrant abdominal pain. Postgrad Med. 1993 Aug;94(2):153-161. doi: 10.1080/00325481.1993.11945700. PMID: 29206611.

  • Revzin MV, Scoutt LM, Garner JG, Moore CL. Right Upper Quadrant Pain: Ultrasound First! J Ultrasound Med. 2017 Oct;36(10):1975-1985. doi: 10.1002/jum.14274. Epub 2017 Jun 6. PMID: 28586152.

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