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Published on: 7/15/2026
Upper right quadrant pain most often signals a problem with the gallbladder, liver, or nearby organs. Common causes include gallstones, cholecystitis (gallbladder inflammation), hepatitis, or liver inflammation. Less frequently, it may stem from the right kidney, pancreas, or intestines. Pain can be sharp, dull, or cramping, and may worsen after eating fatty foods.
Because these conditions range from mild to serious, identifying the cause early matters. Take a free, instant, online symptom check to better understand your symptoms and confidently plan your next steps.
Reviewed for medical accuracy: 07/14/2026
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Submit your own QuestionPain in the upper right side of your belly can have many causes. One common cause is gallbladder problems. In many cases, gallstones (small stones that form in the gallbladder) or cholecystitis (inflammation of the gallbladder) can lead to severe pain in this area, especially after eating fatty meals. The liver, which is also on the right side, can be another source of pain if it is inflamed, as in hepatitis or from other conditions. Sometimes the bile ducts, which carry bile from the liver and gallbladder, can be blocked or inflamed. Other nearby structures like the colon, right kidney, or even parts of the lung may also cause pain that feels like it is coming from the upper right abdomen. Ultrasound is often the first test used because it is good at showing problems with the gallbladder and liver. To help identify what might be causing your symptoms, you can start with a free symptom checker before seeing a healthcare provider for a proper evaluation to determine the exact cause and decide on the best treatment.
(References)
Kingham JG, Dawson AM. Origin of chronic right upper quadrant pain. Gut. 1985 Aug;26(8):783-8. doi: 10.1136/gut.26.8.783. PMID: 4018643; PMCID: PMC1432792.
Rathgaber S, Rex DK. Right upper quadrant abdominal pain. Postgrad Med. 1993 Aug;94(2):153-161. doi: 10.1080/00325481.1993.11945700. PMID: 29206611.
Revzin MV, Scoutt LM, Garner JG, Moore CL. Right Upper Quadrant Pain: Ultrasound First! J Ultrasound Med. 2017 Oct;36(10):1975-1985. doi: 10.1002/jum.14274. Epub 2017 Jun 6. PMID: 28586152.
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