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Published on: 1/29/2026
Bloody, persistent diarrhea is most often caused by gut infections, inflammatory bowel disease (IBD), or local issues such as hemorrhoids or anal fissures. Other possible causes include certain medications, reduced blood flow to the colon (ischemic colitis), parasites, and in some cases, colon polyps or colorectal cancer.
Because the causes range from mild to serious, identifying red flags—like heavy bleeding, fever, dizziness, or severe abdominal pain—is critical, as these signal the need for prompt medical care. Doctors typically diagnose the cause using stool tests, blood work, and sometimes colonoscopy.
Since bloody diarrhea can point to many different conditions, the smartest next step is to clarify your specific symptoms before deciding on care. Take a free, instant, online symptom check to better understand what may be causing your symptoms and get personalized guidance on what to do next.
Reviewed for medical accuracy: 07/02/2026
Diarrhea is common and often short-lived, but when it becomes bloody and persistent, it deserves careful attention. Bloody diarrhea means there is visible blood or dark, tarry material mixed with loose or watery stools. Persistent usually means it lasts more than a few days or keeps coming back. Together, these symptoms can point to irritation, infection, inflammation, or other conditions affecting the digestive tract.
This article explains the most common and credible medical reasons for bloody, ongoing diarrhea, what symptoms to watch for, and when to seek medical care—using clear language without unnecessary alarm.
Blood in diarrhea usually comes from the lower digestive tract, such as the colon or rectum, though darker blood can sometimes come from higher up. The color and amount of blood can offer clues:
Persistent diarrhea means the bowel lining may be inflamed, infected, or damaged, which allows blood to leak into stool.
Certain infections are a leading cause of bloody diarrhea.
Bacterial infections are especially common, including:
These bacteria can enter the body through:
Symptoms often include:
Some parasitic infections can also cause persistent diarrhea with blood, particularly after travel or exposure to untreated water.
Inflammatory bowel disease includes:
These are chronic conditions where the immune system causes ongoing inflammation in the digestive tract.
Common signs include:
IBD is not caused by infection and often requires long-term medical care.
Irritable bowel syndrome (IBS) does not cause bleeding on its own. However, people with IBS may also have:
If you have IBS and notice blood, it's important to look for another cause.
Sometimes blood appears during diarrhea because of local irritation, not disease inside the bowel.
These can cause:
While common, bleeding should still be discussed with a doctor if diarrhea is persistent.
When blood flow to part of the colon is reduced, the tissue can become inflamed and bleed.
This may occur in:
Symptoms can include:
Certain medications can irritate the digestive tract or increase bleeding risk, such as:
Antibiotics can also disrupt healthy gut bacteria, sometimes leading to infections that cause persistent diarrhea with blood.
While less common, ongoing bloody diarrhea can be a sign of:
Other symptoms may include:
Early evaluation improves outcomes, which is why persistent symptoms should not be ignored.
You should speak to a doctor promptly if diarrhea with blood is accompanied by:
These signs may point to a condition that needs urgent evaluation or treatment.
A healthcare professional may recommend:
The goal is to identify the cause and guide appropriate treatment.
While evaluation is important, these steps may help reduce discomfort:
Tracking your symptoms—including frequency, appearance of stool, and associated pain—can help your doctor.
If you're unsure what might be causing your symptoms or need help deciding whether to contact your doctor, a free diarrhea symptom checker can help you assess your condition and understand possible causes based on the symptoms you're experiencing. This tool can be especially useful for organizing your concerns before your medical appointment, though it should never replace professional medical advice.
Bloody and persistent diarrhea is not something to self-diagnose or ignore. Many causes are treatable, especially when addressed early. Others require ongoing care to prevent complications.
If there is any concern that symptoms could be serious or life-threatening, or if bleeding continues, speak to a doctor as soon as possible. Prompt medical advice ensures you get the right tests, treatment, and peace of mind.
Diarrhea that is bloody and persistent often signals inflammation, infection, or damage in the digestive tract. While some causes are mild and temporary, others require medical evaluation. Paying attention to warning signs, staying hydrated, and seeking professional care are the most reliable ways to protect your health.
(References)
* Arasaradnam RP, et al. Chronic Diarrhea: A Clinical Review. Dig Dis. 2018;36(2):108-115. doi: 10.1159/000484732.
* Cosnes J, et al. Inflammatory Bowel Disease: Pathogenesis and Therapeutic Approaches. Gastroenterology. 2015 Oct;149(4):872-887. doi: 10.1053/j.gastro.2015.06.004.
* Crooks L, et al. Diagnosis and Management of Infectious Diarrhea. Curr Treat Options Gastroenterol. 2021 Mar;19(1):1-16. doi: 10.1007/s11938-021-00331-x.
* Schiller LR. Diagnostic approach to chronic diarrhea. Curr Gastroenterol Rep. 2016 Oct;18(10):58. doi: 10.1007/s11894-016-0524-7.
* Guh AY, et al. Approach to Acute Bloody Diarrhea. Infect Dis Clin North Am. 2022 Jun;36(2):339-354. doi: 10.1016/j.idc.2022.03.003.
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