Our Services
Medical Information
Helpful Resources
Published on: 2/10/2026
CoQ10 supports heart health and cellular energy in women over 65, but natural levels decline with age and can drop further with statins, so supplementation may help with stamina, heart function, and even healthy blood pressure when used alongside medical care. There are several factors to consider, including the form you choose, dosing, taking it with food, potential side effects, and interactions with heart or blood pressure medicines; see below for complete details that can guide your next steps with your clinician.
As women move into their mid‑60s and beyond, the body changes in ways that can affect energy, heart health, and overall resilience. One nutrient that often gets overlooked—but plays a critical role in healthy aging—is CoQ10 (short for coenzyme Q10). Understanding what CoQ10 does, why levels decline with age, and how it may support heart and energy health can help women over 65 make informed choices about their wellbeing.
This article draws on findings from respected medical and scientific organizations, cardiology research, and clinical nutrition studies, while keeping the language practical and easy to understand.
CoQ10 is a vitamin‑like compound found naturally in every cell of the body. It has two main jobs:
The heart, brain, muscles, and kidneys contain the highest levels of CoQ10 because they require the most energy to function properly.
It is well established in aging research that natural CoQ10 production decreases with age, often beginning as early as the 40s and becoming more noticeable after 65. Several factors contribute:
For many older women, this decline can quietly affect stamina, heart efficiency, and recovery from daily activities.
Heart health is a major concern for women as they age. Cardiovascular disease remains a leading cause of illness in older women, and symptoms can be more subtle than in men.
The heart is one of the most energy‑dependent organs in the body. CoQ10 supports heart health by:
Clinical studies published in peer‑reviewed cardiology journals have shown that people with heart conditions often have lower CoQ10 levels than healthy individuals. Research has also found that CoQ10 supplementation may support heart function when used alongside standard medical care.
Some studies suggest CoQ10 may help support healthy blood pressure levels by improving blood vessel flexibility and energy metabolism. This does not replace medical treatment, but it may be part of a broader heart‑healthy approach.
If you're experiencing symptoms that concern you or want to understand your risk factors better, using a free Hypertension symptom checker can help you identify important signs to discuss with your doctor.
Many women over 65 notice they "just don't have the energy they used to." While this can have many causes, declining CoQ10 levels are one possible factor.
Without enough CoQ10:
This doesn't usually show up as sudden exhaustion. Instead, it may feel like:
Supporting cellular energy with adequate CoQ10 may help maintain everyday vitality.
Many women over 65 take statins to manage cholesterol. While statins are effective and often necessary, they are known to reduce the body's natural production of CoQ10.
This matters because lower CoQ10 levels have been linked in some studies to:
Not everyone experiences these effects, but it is one reason clinicians sometimes discuss CoQ10 when statins are prescribed—especially in older adults.
Oxidative stress increases with age and contributes to cellular wear and tear. CoQ10 acts as an antioxidant, helping neutralize free radicals that can damage cells.
For women over 65, this antioxidant role may support:
While CoQ10 is not a cure or anti‑aging miracle, it is part of the body's natural defense system.
CoQ10 is found in small amounts in certain foods, including:
However, diet alone usually provides much lower amounts than what has been studied for therapeutic benefits, especially in older adults.
CoQ10 supplements are widely used, particularly by older adults. Two common forms are:
Important considerations:
This is not something to guess at. Speak to a doctor or pharmacist before starting CoQ10, especially if you have heart disease, take blood pressure medication, or use statins.
CoQ10 is generally well tolerated, but it is still biologically active. Mild side effects may include digestive discomfort or headache in some people.
You should always speak to a doctor if you:
Anything that could be life‑threatening or serious should never be self‑treated.
CoQ10 plays a key role in energy production and heart health—two areas that matter deeply as women age. Natural levels decline over time, and common medications may lower them further. For many women over 65, understanding CoQ10 is about supporting the body, not chasing quick fixes.
If you are noticing fatigue, changes in stamina, or concerns about heart health, consider starting with awareness. Tools like a free Hypertension symptom checker can help you prepare for a more informed conversation with your healthcare provider.
Above all, speak to a doctor before making decisions about supplements or addressing symptoms that could be serious. CoQ10 is one piece of a larger health picture, and personalized medical advice is always essential.
(References)
* Mortensen SA, et al. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO—a randomized double-blind trial. JACC Heart Fail. 2014 Dec;2(6):641-9. doi: 10.1016/j.jchf.2014.06.008. Epub 2014 Aug 11. PMID: 25124036.
* Sood S, et al. Coenzyme Q10 and Cardiovascular Disease: A Systematic Review. J Clin Exp Cardiol. 2018 Jan;9(1):1000570. doi: 10.4172/2155-9880.1000570. Epub 2018 Jan 22. PMID: 29881676.
* López-Lluch G, Navas P. Coenzyme Q10 and Aging. J Gerontol A Biol Sci Med Sci. 2016 Oct;71(10):1243-5. doi: 10.1093/gerona/glw002. Epub 2016 Feb 9. PMID: 26865247.
* Fan L, et al. Effects of coenzyme Q10 supplementation on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2017 Apr;118:105-113. doi: 10.1016/j.phrs.2017.02.003. Epub 2017 Feb 9. PMID: 28189608.
* Zhang P, et al. The effect of coenzyme Q10 supplementation on blood pressure: A systematic review and meta-analysis. Front Cardiovasc Med. 2023 Apr 12;10:1143872. doi: 10.3389/fcvm.2023.1143872. PMID: 37113106; PMCID: PMC10129712.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.