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Published on: 2/10/2026
Fast, effective relief after 65 often uses OTC azole treatments like clotrimazole or miconazole in 7 day courses, with prescription options such as fluconazole or extended regimens for tougher or recurrent cases, but evaluation is key since symptoms can mimic other conditions. See below to understand more. To prevent recurrences, focus on moisture control, diabetes management, careful antibiotic use, and discussing vaginal estrogen when appropriate, and know when to see a doctor if symptoms persist, recur, or include pain, sores, bleeding, fever, or pelvic pain. There are several factors to consider, including drug interactions and safety screening, so see below for important details that can guide your next steps.
Yeast infections, also known as candidal vulvovaginitis, can occur at any age—but after 65, they may feel different, last longer, or come back more often. Changes related to aging, medications, and chronic health conditions can affect how the body responds to yeast overgrowth. The good news is that effective yeast infection treatment is available, and with the right approach, most people can find relief and reduce the chance of recurrence.
This guide explains safe, evidence-based options for treatment and prevention after age 65, using clear language and practical steps.
A yeast infection happens when Candida (a naturally occurring fungus) grows too much in the vaginal area. After menopause and later in life, several factors can increase risk:
These changes do not mean yeast infections are inevitable—but they do mean treatment may need to be more individualized.
Symptoms of a yeast infection after 65 are often similar to those at younger ages, but they can overlap with other conditions. Common signs include:
Because symptoms can mimic other issues—such as bacterial infections, skin conditions, or vaginal atrophy—it's important not to self-diagnose repeatedly.
If you're experiencing these symptoms and want to better understand what might be causing them, try using a free Candidal Vulvovaginitis (Yeast Infection) symptom checker to get personalized insights before deciding on your next steps.
For mild, occasional infections, many people find relief with OTC antifungal products. These are widely recommended by medical guidelines.
Common options include:
They come as:
What to know after 65:
If symptoms do not improve within a few days or return quickly, stop self-treatment and speak to a doctor.
For moderate, severe, or recurrent infections, a healthcare provider may prescribe:
These options are supported by long-standing clinical evidence and are often more effective when OTC treatments fail.
Important considerations:
In postmenopausal adults, symptoms that feel like a yeast infection may be caused by other conditions, such as:
In these cases, antifungal treatment will not help and may worsen irritation. This is why medical evaluation is especially important if infections seem frequent or resistant.
Along with proper yeast infection treatment, these steps may help reduce discomfort:
These steps support healing but do not replace antifungal treatment when an infection is present.
Prevention is especially important if you've had more than one infection in a year.
Some people ask about probiotics or dietary changes. Current medical evidence suggests:
Always talk to a healthcare provider before starting supplements, especially if you take multiple medications.
While most yeast infections are not dangerous, some situations require medical attention:
If anything feels severe, unusual, or life-threatening, speak to a doctor promptly. Early evaluation can prevent complications and ensure the right diagnosis.
If you're uncertain about your symptoms, a free online Candidal Vulvovaginitis (Yeast Infection) symptom checker can be a helpful starting point—but it should never replace professional medical advice.
With the right information and support, most people over 65 can find fast relief and reduce the risk of future yeast infections.
(References)
* Donders GGG, Bellen G, De Sutter P. Vulvovaginal Candidiasis in Postmenopausal Women. Int J Gynaecol Obstet. 2017 Jan;136(1):15-18. doi: 10.1002/ijgo.12009. Epub 2016 Nov 1. PMID: 27726194.
* Sobel JD. Vulvovaginal Candidiasis: Epidemiology, Diagnosis, and Management. Am J Obstet Gynecol. 2021 Jan;224(1):1-10. doi: 10.1016/j.ajog.2020.07.018. Epub 2020 Aug 6. PMID: 32777322.
* Pappas PG, Sobel JD. Recurrent Vulvovaginal Candidiasis: An Update on Epidemiology, Pathogenesis, and Management. Sex Transm Dis. 2020 Sep;47(9):561-568. doi: 10.1097/OLQ.0000000000001217. PMID: 32796468.
* Marra V, Ghasemian R, Donders GGG. Topical and Oral Antifungal Agents for the Treatment of Vulvovaginal Candidiasis: A Review of Efficacy and Safety. Pharmaceuticals (Basel). 2023 Apr 15;16(4):597. doi: 10.3390/ph16040597. PMID: 37111005.
* Donders GGG, Ravel J, Bellen G, Van der Meersch E. Estrogen and Fungal Infection: A Complex Relationship. J Fungi (Basel). 2022 Nov 22;8(12):1224. doi: 10.3390/jof8121224. PMID: 36556100.
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