Acute Generalized Exanthematous Pustulosis (AGEP) Quiz

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Redness of the skin

A pimple

Wound

Red bumps with white centers

Red spots on skin

Scab

Pus in the breast

Not seeing your symptoms? No worries!

What is Acute Generalized Exanthematous Pustulosis (AGEP)?

AGEP is a severe reaction, often caused by drugs, that appears as numerous small pustules on the skin with swelling and redness. It usually starts on the face and can spread to the trunk and limbs. The reaction often begins a few hours to days after taking the offending drug, most commonly antibiotics, antifungals, and antimalarials.

Typical Symptoms of Acute Generalized Exanthematous Pustulosis (AGEP)

Diagnostic Questions for Acute Generalized Exanthematous Pustulosis (AGEP)

Your doctor may ask these questions to check for this disease:

  • Is your whole body red?
  • Have you started a new medication recently?
  • Do you have pus-filled blisters or bumps on your skin?
  • Did you have fever or skin lumps/bumps 2 to 6 weeks after starting new medication?
  • Did you develop a rash after taking medication?

Treatment of Acute Generalized Exanthematous Pustulosis (AGEP)

The main treatment for AGEP is immediately stopping the causative agent. For symptom relief, medications like corticosteroids (oral or applied) may be prescribed to suppress inflammation.

Reviewed By:

Sarita Nori, MD

Sarita Nori, MD (Dermatology)

Dr. Sarita Nori was drawn to dermatology because of the intersection of science and medicine that is at the heart of dermatology. She feels this is what really allows her to help her patients. “There is a lot of problem-solving in dermatology and I like that,” she explains. “It’s also a profession where you can help people quickly and really make a difference in their lives.” | Some of the typical skin problems that Dr. Nori treats include skin cancers, psoriasis, acne, eczema, rashes, and contact dermatitis. Dr Nori believes in using all possible avenues of treatment, such as biologics, especially in patients with chronic diseases such as eczema and psoriasis. “These medications can work superbly, and they are really life-changing for many patients.” | Dr. Nori feels it’s important for patients to have a good understanding of the disease or condition that is affecting them. “I like to educate my patients on their problem and have them really understand it so they can take the best course of action. Patients always do better when they understand their skin condition, and how to treat it.”

Yukiko Ueda, MD

Yukiko Ueda, MD (Dermatology)

Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.

From our team of 50+ doctors

Content updated on Feb 13, 2025

Following the Medical Content Editorial Policy

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