Anosacral Cutaneous Amyloidosis Quiz

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Yukiko Ueda

Yukiko Ueda, MD (Dermatology)

Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.

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People with these symptoms also use Ubie's symptom checker to find possible causes

  • Skin tightness of the fingers

  • Increase in dandruff

  • Black/blue/brown spots or moles, on the skin and lining of the mouth

  • Moles or spots of different colors on skin or lining of the mouth

  • Scars or marks from the rash/wound

  • Even more dandruff now

  • Hard fingertips

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Learn more about Anosacral cutaneous amyloidosis

Content updated on Sep 20, 2022

What is anosacral cutaneous amyloidosis?

Anosacral cutaneous amyloidosis is a rare condition that affects the skin from the anus to the sacral region (bottom of the spine). It occurs due to abnormal protein deposits in the skin. The exact cause is unclear, and it is more common among Asians.

Symptoms of anosacral cutaneous amyloidosis

  • Black/blue/brown spots or moles, on the skin and lining of the mouth

  • Scaly skin that flakes off

  • Skin hardening

Questions your doctor may ask to check for anosacral cutaneous amyloidosis

Your doctor may ask these questions to diagnose anosacral cutaneous amyloidosis

  • Are there black, blue, or brown spots on the skin or elsewhere? (Including moles)

  • Do you have scaly skin that flakes off?

  • Do you have hardening of the skin?

Treatment for anosacral cutaneous amyloidosis

There is no single standardized effective treatment. Various therapies, including medicated creams or ointments, phototherapy, oral medication, and laser therapy are used.

View the symptoms of Anosacral cutaneous amyloidosis

References

  • Wang WJ, Huang CY, Chang YT, Wong CK. Anosacral cutaneous amyloidosis: a study of 10 Chinese cases. Br J Dermatol. 2000 Dec;143(6):1266-9. doi: 10.1046/j.1365-2133.2000.03899.x. PMID: 11122031.

    https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2133.2000.03899.x

User testimonials

Reviewed By:

Yukiko Ueda

Yukiko Ueda, MD (Dermatology)

Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.

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