Overview
Kidney stones and urinary tract infections can both cause pain during urination and discomfort in the lower abdomen. While UTIs typically cause burning urination and frequent urges to urinate, kidney stones often cause more intense, sharp pain that may radiate to the back or side.
Disease Summaries
Kidney Stones: This condition involves hard deposits made of minerals and salts that form inside the kidneys, causing severe pain as they pass through the urinary tract. The stones can vary in size from as small as a grain of sand to as large as a golf ball, with symptoms including severe back pain, nausea, and painful urination. They are often caused by dehydration, dietary factors, obesity, and certain medical conditions that affect mineral metabolism.
UTI: A urinary tract infection (UTI) refers to an infection in any part of the urinary system, most commonly affecting the bladder and urethra. The infection typically occurs when bacteria enter the urinary tract through the urethra and multiply in the bladder, causing symptoms such as burning during urination, frequent urges to urinate, and cloudy urine. Women are at higher risk due to their shorter urethra, and recurrent infections are common.
Comparing Symptoms
Overlapping Symptoms
- Pain during urination
- Frequent urination
- Lower abdominal discomfort
- Cloudy urine
Kidney Stones Specific Symptoms
- Severe, sharp pain in back/side
- Pain comes in waves
- Blood in urine
- Nausea/vomiting
- Pain changes with position
UTI Specific Symptoms
- Burning sensation when urinating
- Persistent urge to urinate
- Strong-smelling urine
- Pelvic pressure
- Low-grade fever
Treatment Approaches
Kidney Stones Treatment Approaches
Treatment depends on stone size and severity, ranging from pain management and hydration for small stones that may pass naturally, to medical procedures like shock wave lithotripsy or surgery for larger stones. Medications can help manage pain and sometimes help stones pass more easily. Prevention includes dietary changes and increased fluid intake.
UTI Treatment Approaches
Treatment typically involves a course of antibiotics specific to the type of bacteria causing the infection, along with pain relievers for discomfort. Increased fluid intake helps flush out bacteria, and preventive measures include proper hygiene and urinating after sexual activity. For recurrent UTIs, long-term preventive antibiotics might be prescribed.
Reviewed By:

Kenji Taylor, MD, MSc (Family Medicine, Primary Care)
Dr. Taylor is a Japanese-African American physician who grew up and was educated in the United States but spent a considerable amount of time in Japan as a college student, working professional and now father of three. After graduating from Brown, he worked in finance first before attending medical school at Penn. He then completed a fellowship with the Centers for Disease Control before going on to specialize in Family and Community Medicine at the University of California, San Francisco (UCSF) where he was also a chief resident. After a faculty position at Stanford, he moved with his family to Japan where he continues to see families on a military base outside of Tokyo, teach Japanese residents and serve remotely as a medical director for Roots Community Health Center. He also enjoys editing and writing podcast summaries for Hippo Education.

Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
Content updated on Mar 13, 2024
Following the Medical Content Editorial Policy
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Ripa F, Pietropaolo A, Montanari E, Hameed BMZ, Gauhar V, Somani BK. Association of Kidney Stones and Recurrent UTIs: the Chicken and Egg Situation. A Systematic Review of Literature. Curr Urol Rep. 2022 Sep;23(9):165-174. doi: 10.1007/s11934-022-01103-y. Epub 2022 Jul 25. PMID: 35877059; PMCID: PMC9492590.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9492590/Brain E, Geraghty RM, Cook P, Roderick P, Somani B. Risk of UTI in kidney stone formers: a matched-cohort study over a median follow-up of 19 years. World J Urol. 2021 Aug;39(8):3095-3101. doi: 10.1007/s00345-020-03564-7. Epub 2021 Jan 5. PMID: 33403436; PMCID: PMC8405492.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8405492/Zheng, Z., Hu, W., Ji, C. et al. A study of the difference in biochemical metabolism between patients with unilateral and bilateral upper urinary tract stones. Sci Rep 14, 30154 (2024).
https://www.nature.com/articles/s41598-024-81454-3