Overview
Urinary Tract Infections (UTIs) and Sexually Transmitted Diseases (STDs) can both cause discomfort during urination and changes in genital discharge, but they have different causes and implications. UTIs are bacterial infections that affect parts of the urinary system, most commonly the bladder. STDs are infections transmitted through sexual contact and can be caused by bacteria, viruses, or parasites. While UTIs are not sexually transmitted, sexual activity can increase UTI risk. STDs often require different treatment and follow-up due to potential long-term health effects.
Disease Summaries
UTI: A urinary tract infection (UTI) refers to an infection in any part of the urinary system, most commonly affecting the bladder and urethra. The infection typically occurs when bacteria enter the urinary tract through the urethra and multiply in the bladder, causing symptoms such as burning during urination, frequent urges to urinate, and cloudy urine. Women are at higher risk due to their shorter urethra, and recurrent infections are common.
STD: STDs including chlamydia, gonorrhea, syphilis, and HIV are infections primarily spread through sexual contact. Chlamydia and gonorrhea are bacterial infections that can cause pain during urination, abnormal discharge, and pelvic discomfort, but often show no symptoms. Syphilis progresses in stages, starting with painless sores and potentially leading to serious complications if untreated. HIV is a viral infection that weakens the immune system over time and can lead to AIDS if not managed. Early detection and treatment are crucial to prevent long-term health effects and transmission.
Comparing Symptoms
Overlapping Symptoms
- Burning sensation during urination
- Pelvic or lower abdominal discomfort
- Increased urge to urinate
- Unusual discharge from the urethra or vagina
UTI Specific Symptoms
- Frequent, urgent urination with small amounts
- Cloudy, strong-smelling, or bloody urine
- Pain in the lower back or bladder area
- Fever (in more severe or kidney-related infections)
- Typically responds quickly to antibiotics
STD Specific Symptoms
- Genital sores or blisters (e.g., herpes)
- Unusual genital discharge (yellow, green, or foul-smelling)
- Pain during sex or urination
- Swollen lymph nodes or fever (in some cases)
- May be asymptomatic or persistent without treatment
Treatment Approaches
UTI Treatment Approaches
Treatment typically involves a course of antibiotics specific to the type of bacteria causing the infection, along with pain relievers for discomfort. Increased fluid intake helps flush out bacteria, and preventive measures include proper hygiene and urinating after sexual activity. For recurrent UTIs, long-term preventive antibiotics might be prescribed.
STD Treatment Approaches
STDs are typically treated with antibiotics, often as a single dose or short course. HIV is managed with antiretroviral therapy (ART), a combination of medications taken daily to control the virus and prevent transmission.
Reviewed By:

Kenji Taylor, MD, MSc (Family Medicine, Primary Care)
Dr. Taylor is a Japanese-African American physician who grew up and was educated in the United States but spent a considerable amount of time in Japan as a college student, working professional and now father of three. After graduating from Brown, he worked in finance first before attending medical school at Penn. He then completed a fellowship with the Centers for Disease Control before going on to specialize in Family and Community Medicine at the University of California, San Francisco (UCSF) where he was also a chief resident. After a faculty position at Stanford, he moved with his family to Japan where he continues to see families on a military base outside of Tokyo, teach Japanese residents and serve remotely as a medical director for Roots Community Health Center. He also enjoys editing and writing podcast summaries for Hippo Education.

Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
Content updated on May 1, 2025
Following the Medical Content Editorial Policy
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https://pmc.ncbi.nlm.nih.gov/articles/PMC9492590/Brain E, Geraghty RM, Cook P, Roderick P, Somani B. Risk of UTI in kidney stone formers: a matched-cohort study over a median follow-up of 19 years. World J Urol. 2021 Aug;39(8):3095-3101. doi: 10.1007/s00345-020-03564-7. Epub 2021 Jan 5. PMID: 33403436; PMCID: PMC8405492.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8405492/Torrone E, Papp J, Weinstock H, (2014). Prevalence of Chlamydia trachomatis genital infection among persons aged 14-39 years--United States, 2007-2012. MMWR. Morbidity and mortality weekly report.
https://pubmed.ncbi.nlm.nih.gov/25254560/