Extramammary Paget's Disease Quiz

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Alice Police, MD

Alice Police, MD (Breast Surgery)

Breast Surgeon of 30 years experience. Recent Chief of breast surgery at UCIrvine Medical Center, Northwell Health in New York State, Chief of breast surgery at Monument Health in Rapid City South Dakota. Breast Cancer Researcher in conjunction with multiple studies through Notre Dame department of electrical engineering. CMO of Nearwave, a start up breast cancer device company.

Yoshinori Abe, MD

Yoshinori Abe, MD (Internal Medicine)

Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.

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Content updated on Mar 31, 2024

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People with similar symptoms also use Ubie's symptom checker to find possible causes

  • Patches of skin with no pigmentation with patches of pigmentation inside

  • Moles or spots of different colors on skin or lining of the mouth

  • Lumps under skin

  • Patches of skin with no pigmentation that look like a map

  • Increase in dandruff

  • The skin is itchy and has scratches

  • White skin has white hairs growing from it

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What is Extramammary Paget's Disease?

Skin rashes can be VERY confusing. Most are due to contact with something irritating and are easily treated with over the counter creams. However, there are some that need to be seen by a physician and possibly biopsied. One of these is Extramammary Paget's disease (EMPD). It is a scaly, raised red to pink and grey rash that occurs most commonly where the skin is folded over such as the armpits, the genital areas, or the groin in men or women. EMPD is often ignored or diagnosed late due to its innocent appearance. It is important to see a physician if you have a rash in these areas that does not go away as it may be cancerous. Multiple treatments are available and patients do well when it is caught early.

Typical Symptoms of Extramammary Paget's Disease

  • Black/blue/brown spots or moles, on the skin and lining of the mouth

  • a white spot

  • Skin Itching

  • Lumps under the skin

  • Scaly skin that flakes off

  • Scab

  • Skin redness or red bumpy rashes

Doctor's Diagnostic Questionson Extramammary Paget's Disease

Your doctor may ask these questions to check for this disease:

  • Are there black, blue, or brown spots on your skin? (Including moles)

  • Is your skin itchy?

  • Do you have any lumps under your skin?

  • Do you have flaky, scaly skin?

  • Do you have a scab?

Treatmentof Extramammary Paget's Disease

The standard treatment is surgical removal of the cancer. Radiotherapy, chemotherapy, and targeted therapies may also be used depending on the exact nature of the underlying tumor if one is found. Surgical resection is the preferred treatment, however some lesions may not be easily removed surgically and may require radiation therapy or chemotherapy. There are also surface treatments such as lasers or photodynamic therapy that may be used. Close monitoring after successful treatment should be done for at least 5 years.

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References

  • Evidence-Based Clinical Practice Guidelines for Extra-mammary Paget Disease JAMA Oncology Special Communication January 20, 2022

    https://jamanetwork.com/journals

User Testimonials

Reviewed By:

Alice Police, MD

Alice Police, MD (Breast Surgery)

Breast Surgeon of 30 years experience. Recent Chief of breast surgery at UCIrvine Medical Center, Northwell Health in New York State, Chief of breast surgery at Monument Health in Rapid City South Dakota. Breast Cancer Researcher in conjunction with multiple studies through Notre Dame department of electrical engineering. CMO of Nearwave, a start up breast cancer device company.

Yoshinori Abe, MD

Yoshinori Abe, MD (Internal Medicine)

Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.

From our team of 50+ doctors

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Maxwell J. Nanes, DO

Maxwell J. Nanes, DO

Emergency Medicine

Waukesha Memorial Hospital, Waukesha Wisconsin, USA

Caroline M. Doan, DO

Caroline M. Doan, DO

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Signify Health

Benjamin Kummer, MD

Benjamin Kummer, MD

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Icahn School of Medicine at Mount Sinai

Charles Carlson, DO, MS

Charles Carlson, DO, MS

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U.S. Department of Veterans Affairs

Dale Mueller, MD

Dale Mueller, MD

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Ravi P. Chokshi, MD

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