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Gastric discomfort
Heartburn
Pain in the middle of the upper stomach
Stomachache
Abdominal discomfort
Have nausea
Pressure in the stomach
Not seeing your symptoms? No worries!
A condition where the stomach's surface lining is inflamed. Weaknesses or injury to the mucus-lined barrier that usually protect the stomach wall allow digestive juices to damage and inflame the stomach lining. A number of diseases and conditions can increase the risk of gastritis, including a bacteria infection called H. pylori. Some symptoms are belly ache, belly pain, nausea and vomiting.
Your doctor may ask these questions to check for this disease:
Treatment depends on the cause. You may be prescribed antibiotics to kill H. pylori bacteria or drugs to block or reduce gastric acid levels. Some patients may find relief through lifestyle changes like avoiding alcohol and spicy food, and stopping medicines that affect the stomach lining.
Reviewed By:
Samantha Nazareth, MD (Gastroenterology)
Board-certified gastroenterologist. Experience managing gastrointestinal conditions (GERD, IBS, ulcerative colitis, Crohn’s, celiac disease, NASH) within healthcare organizations (three ambulatory surgical centers, single-specialty practice, multi-specialty practice and solo practice).
Aiko Yoshioka, MD (Gastroenterology)
Dr. Yoshioka graduated from the Niigata University School of Medicine. He worked as a gastroenterologist at Saiseikai Niigata Hospital and Niigata University Medical & Dental Hospital before serving as the Deputy Chief of Gastroenterology at Tsubame Rosai Hospital and Nagaoka Red Cross Hospital. Dr. Yoshioka joined Saitama Saiseikai Kawaguchi General Hospital as Chief of Gastroenterology in April 2018.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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Q.
Chronic Indigestion? Why Your Stomach is Burning: Medical Next Steps
A.
Persistent stomach burning with chronic indigestion is most often due to gastritis, acid reflux or peptic ulcers, sometimes from H. pylori or NSAID use; typical next steps include reviewing medications, testing and treating H. pylori, trying acid-reducing therapy, and considering endoscopy if symptoms persist or red flags appear. There are several factors to consider, including functional dyspepsia and urgent warning signs like vomiting blood, black stools, severe pain, trouble swallowing or weight loss; see below for when to seek care, how long to wait, and the specific lifestyle changes that can help right now.
References:
* Sperber AD, Shmueli A. Functional dyspepsia: a review of the pathophysiology and current management. World J Gastroenterol. 2017 Jul 21;23(27):4844-4861. doi: 10.3748/wjg.v23.i27.4844. PMID: 28761298; PMCID: PMC5530754.
* Katz PO, Gerson LB, Vela MF. Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol. 2013 May;108(5):841-57; quiz 858. doi: 10.1038/ajg.2013.194. Epub 2013 Apr 23. PMID: 23629695; PMCID: PMC3735017.
* Ford AC, et al. Diagnosis and management of uninvestigated dyspepsia: British Society of Gastroenterology and Association of Upper Gastrointestinal Surgeons guidelines. Gut. 2017 Oct;66(10):1725-1738. doi: 10.1136/gutjnl-2017-314081. Epub 2017 Aug 16. PMID: 28814421.
* Katz PO, et al. ACG Clinical Guideline: Management of Heartburn Not Responding to Proton Pump Inhibitors. Am J Gastroenterol. 2022 Jul 1;117(7):955-971. doi: 10.14309/ajg.0000000000001831. Epub 2022 Jun 29. PMID: 35767591.
* Parkman HP, et al. Gastroparesis: diagnosis and management. Nat Rev Gastroenterol Hepatol. 2021 Aug;18(8):570-588. doi: 10.1038/s41575-021-00441-2. Epub 2021 May 14. PMID: 33990868.
Q.
Stomach on Fire? Why Gastritis is Gnawing at You & Medically-Approved Next Steps
A.
Burning or gnawing pain high in your abdomen is often gastritis, usually triggered by H. pylori, NSAIDs, alcohol, or illness, and it is typically treatable with targeted steps like testing for H. pylori, removing irritants, and short-term acid reducers. There are several factors to consider, including red flag symptoms that need urgent care and cause-specific treatments that can change your next steps; see below for complete guidance on tests, when antibiotics plus PPIs are needed, safer pain reliever options, B12 and autoimmune issues, and practical diet and stress tips.
References:
* Wickramasinghe, N., & Indika Karunathilake, L. (2022). Gastritis: a review of the current evidence for diagnosis and treatment. *World Journal of Gastroenterology*, *28*(12), 1201–1215.
* Malfertheiner, P., Megraud, F., O'Morain, C. A., Atherton, J., Axon, A. T. R., Bazzoli, F., ... & Seppälä, N. (2024). Management of Helicobacter pylori infection: The Maastricht VI/Florence Consensus Report. *Gut*.
* Venerito, M., Klessen, C. D., & Malfertheiner, P. (2020). Autoimmune Gastritis: Pathophysiology and Clinical Relevance of Serological Markers. *International Journal of Molecular Sciences*, *21*(8), 2825.
* Gao, X. J., & Luo, H. S. (2020). Diagnosis and Treatment of Chronic Gastritis: An Evidence-Based Approach. *Chinese Medical Journal (English)*, *133*(20), 2418–2426.
* Nishimura, Y., Satoh, T., Ishikawa, T., & Takechi, M. (2021). Non-steroidal anti-inflammatory drug (NSAID)-induced gastritis: An update on diagnosis and management. *World Journal of Gastroenterology*, *27*(28), 4530–4545.
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1Sipponen P, Maaroos HI. Chronic gastritis. Scand J Gastroenterol. 2015 Jun;50(6):657-67. doi: 10.3109/00365521.2015.1019918. Epub 2015 Apr 22. PMID: 25901896; PMCID: PMC4673514.
https://www.tandfonline.com/doi/full/10.3109/00365521.2015.1019918Mihály E, Micsik T, Juhász M, Herszényi L, Tulassay Z. Gastritisek és gastropathiák [Gastritis and gastropathy]. Orv Hetil. 2014 Jan 12;155(2):43-61. Hungarian. doi: 10.1556/OH.2014.29807. PMID: 24389321.
https://akjournals.com/view/journals/650/155/2/article-p43.xmlAnnibale B, Esposito G, Lahner E. A current clinical overview of atrophic gastritis. Expert Rev Gastroenterol Hepatol. 2020 Feb;14(2):93-102. doi: 10.1080/17474124.2020.1718491. Epub 2020 Jan 24. PMID: 31951768.
https://www.tandfonline.com/doi/full/10.1080/17474124.2020.1718491Taylor KB. Gastritis. N Engl J Med. 1969 Apr 10;280(15):818-20. doi: 10.1056/NEJM196904102801507. PMID: 4887251.
https://www.nejm.org/doi/full/10.1056/NEJM196904102801507