Reviewed By:
Phillip Aguila, MD, MBA (Pulmonology, Critical Care)
Dr. Aguila graduated from West Virginia University School of Medicine. He has trained in Pulmonary and Critical Care Medicine at The University of North Carolina in Chapel Hill and Internal Medicine at Medical College of Pennsylvania/Hahnemann University at Allegheny General Hospital in Pittsburgh Pennsylvania. He has served as Assistant Professor since 2010.
Eisaku Kamakura, MD (Pulmonology)
Dr. Kamakura graduated from the Tokyo Medical and Dental University, School of Dentistry, and the Niigata University School of Medicine. He trained at Yokosuka Kyosai Hospital and held positions in the Respiratory Medicine departments at Yokosuka Kyosai Hospital, Tokyo Medical and Dental University, Ome City General Hospital, and Musashino Red Cross Hospital. In 2021, he became the specially appointed assistant professor at the Department of General Medicine, Niigata University School of Medicine.
Content updated on Mar 31, 2024
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Frequent and violent coughing
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Idiopathic pulmonary fibrosis (IPF) is a lung disease with no known cause. It involves damage to air sacs and scarring, causing stiffness in the lungs and difficulty breathing. Risk factors include exposure to certain types of dust (metal or wood), viral infections, smoking, acid reflux disease, and a family history of IPF.
There is no cure for idiopathic pulmonary fibrosis (IPF). Treatment focuses on medication and other therapies to relieve symptoms as much as possible and slow down its progression.
Richeldi L, Collard HR, Jones MG. Idiopathic pulmonary fibrosis. Lancet. 2017 May 13;389(10082):1941-1952. doi: 10.1016/S0140-6736(17)30866-8. Epub 2017 Mar 30. PMID: 28365056.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)30866-8/fulltextLederer DJ, Martinez FJ. Idiopathic Pulmonary Fibrosis. N Engl J Med. 2018 May 10;378(19):1811-1823. doi: 10.1056/NEJMra1705751. PMID: 29742380.
https://www.nejm.org/doi/10.1056/NEJMra1705751Martinez FJ, Collard HR, Pardo A, Raghu G, Richeldi L, Selman M, Swigris JJ, Taniguchi H, Wells AU. Idiopathic pulmonary fibrosis. Nat Rev Dis Primers. 2017 Oct 20;3:17074. doi: 10.1038/nrdp.2017.74. PMID: 29052582.
https://www.nature.com/articles/nrdp201774Spagnolo P, Kropski JA, Jones MG, Lee JS, Rossi G, Karampitsakos T, Maher TM, Tzouvelekis A, Ryerson CJ. Idiopathic pulmonary fibrosis: Disease mechanisms and drug development. Pharmacol Ther. 2021 Jun;222:107798. doi: 10.1016/j.pharmthera.2020.107798. Epub 2020 Dec 24. PMID: 33359599; PMCID: PMC8142468.
https://www.sciencedirect.com/science/article/abs/pii/S0163725820303296?via%3DihubKing TE Jr, Pardo A, Selman M. Idiopathic pulmonary fibrosis. Lancet. 2011 Dec 3;378(9807):1949-61. doi: 10.1016/S0140-6736(11)60052-4. Epub 2011 Jun 28. PMID: 21719092.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(11)60052-4/fulltextMale, 30s
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(Sep 25, 2024)
Reviewed By:
Phillip Aguila, MD, MBA (Pulmonology, Critical Care)
Dr. Aguila graduated from West Virginia University School of Medicine. He has trained in Pulmonary and Critical Care Medicine at The University of North Carolina in Chapel Hill and Internal Medicine at Medical College of Pennsylvania/Hahnemann University at Allegheny General Hospital in Pittsburgh Pennsylvania. He has served as Assistant Professor since 2010.
Eisaku Kamakura, MD (Pulmonology)
Dr. Kamakura graduated from the Tokyo Medical and Dental University, School of Dentistry, and the Niigata University School of Medicine. He trained at Yokosuka Kyosai Hospital and held positions in the Respiratory Medicine departments at Yokosuka Kyosai Hospital, Tokyo Medical and Dental University, Ome City General Hospital, and Musashino Red Cross Hospital. In 2021, he became the specially appointed assistant professor at the Department of General Medicine, Niigata University School of Medicine.
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