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Gastric discomfort
Lymph swollen
Lost weight recently
Fatigued
Unintentional weight loss of more than 5% in one month
Swelling in the neck
Soft tissue lumps
Not seeing your symptoms? No worries!
What is MALT Lymphoma?
MALT lymphoma is a form of lymphoma (cancer of the lymph system) that can occur in any mucosal site, often in the stomach. Its name comes from the immune cells of mucosa-associated lymphoid tissue (MALT). MALT originates from lymphoid tissue aggregates found in mucosal membranes like the gastrointestinal tract, nose, throat, thyroid, breast, lung, salivary glands, eye, and skin. It is sometimes associated with Hepatitis C and H pylori infections and some autoimmune conditions. Symptoms and workup depend on location but the diagnosis is always made with a biopsy.
Treatment of MALT Lymphoma
Many cases of MALT lymphoma can be cured. Treatments include antibiotics, radiotherapy, chemotherapy, immunotherapy, or a combination of treatments and sometimes early stage cases are carefully observed with active surveillance.
Reviewed By:
Robin Schoenthaler, MD (Oncology)
Board certified radiation oncologist with over 30 years experience treating cancer patients. Senior physician advisor for expert medical options in adult oncology. Published award-winning essayist on medical and health issues and more.
Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Violeta Filip P, Cuciureanu D, Sorina Diaconu L, Maria Vladareanu A, Silvia Pop C. MALT lymphoma: epidemiology, clinical diagnosis and treatment. J Med Life. 2018 Jul-Sep;11(3):187-193. doi: 10.25122/jml-2018-0035. PMID: 30364585; PMCID: PMC6197515.
https://medandlife.org/wp-content/uploads/JMedLife-11-187.pdfHollie N, Asakrah S. MALT lymphoma of the colon: a clinicopathological review. J Clin Pathol. 2020 Jul;73(7):378-383. doi: 10.1136/jclinpath-2019-206377. Epub 2020 Feb 7. PMID: 32034054.
https://jcp.bmj.com/content/73/7/378Raderer M, Kiesewetter B, Ferreri AJ. Clinicopathologic characteristics and treatment of marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). CA Cancer J Clin. 2016 Mar-Apr;66(2):153-71. doi: 10.3322/caac.21330. Epub 2015 Nov 24. PMID: 26773441.
https://onlinelibrary.wiley.com/resolve/doi?DOI=10.3322/caac.21330Marcelis L, Tousseyn T, Sagaert X. MALT Lymphoma as a Model of Chronic Inflammation-Induced Gastric Tumor Development. Curr Top Microbiol Immunol. 2019;421:77-106. doi: 10.1007/978-3-030-15138-6_4. PMID: 31123886.
https://link.springer.com/chapter/10.1007/978-3-030-15138-6_4