Perforating Dermatosis Quiz

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Yukiko Ueda

Yukiko Ueda, MD (Dermatology)

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Learn more about Perforating Dermatosis

Content updated on Sep 20, 2022

What is perforating dermatosis?

Perforating dermatosis is a group of skin disorders characterized by perforation or elimination of connective tissue through the skin. It mainly occurs in people suffering from chronic diseases like Diabetes, kidney diseases, liver disease, cancer, thyroid disease or HIV.

Symptoms of perforating dermatosis

  • Lumps under the skin

Questions your doctor may ask to check for perforating dermatosis

Your doctor may ask these questions to diagnose perforating dermatosis

  • Do you feel a lump/lumps under your skin?

Treatment for perforating dermatosis

perforating dermatoses can be treated by anti-inflammatory medication, medications applied to break down skin cells and reduce inflammation. The underlying disease requires treatment first.

View the symptoms of Perforating Dermatosis


  • Ladouce F, Beltzung F, Soubrier M. Perforating dermatosis in rheumatoid arthritis. Rheumatology (Oxford). 2021 Dec 24;61(1):468. doi: 10.1093/rheumatology/keab311. PMID: 33769472.

  • Grover C, Kharghoria G, Sharma S. Acquired perforating dermatosis: Response to colchicine. Dermatol Ther. 2020 Nov;33(6):e14492. doi: 10.1111/dth.14492. Epub 2020 Nov 9. PMID: 33135817.

  • Fisher RM, Hadley G, Ieremia E, Moswela O, Zaki F, DeLuca GC, McPherson T. Natalizumab-induced acquired perforating dermatosis. Clin Exp Dermatol. 2021 Oct;46(7):1373-1375. doi: 10.1111/ced.14699. Epub 2021 Jun 4. PMID: 34086353.

Reviewed By:

Yukiko Ueda

Yukiko Ueda, MD (Dermatology)

From our team of 50+ doctors

Just 3 minutes.
Developed by doctors.

Ubie is supervised by 50+ medical experts worldwide

Shohei Harase

Shohei Harase, MD


Kameda Medical Center, Japan

Yu Shirai

Yu Shirai, MD


Yotsuya Yui Clinic, Japan

Yoshinori Abe

Yoshinori Abe, MD

Internal medicine

Co-founder of Ubie, Inc.

Rohini R

Rohini R, MD

Ear, nose, throat (ENT)

Bayshore Health Centre, India

Seiji Kanazawa

Seiji Kanazawa, MD, PHD

Obstetrics and gynecology (OBGYN)

National Center for Child Health and Development, Japan

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