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Published on: 1/29/2026
Red flags include severe or worsening pain, fever, persistent vomiting or inability to keep fluids down, blood in stool or vomit, chest pain or shortness of breath, unexplained weight loss or loss of appetite, jaundice, and any severe pain during pregnancy. There are several factors to consider, including higher risk in older adults, people with weakened immunity, cancer history, or known organ disease. See below for important details that can guide whether to call your doctor now or seek urgent care.
Abdominal pain is one of the most common reasons people seek medical advice. It can range from mild discomfort after a meal to severe, sudden pain that signals a medical emergency. Most abdominal pain is not dangerous and improves on its own. However, certain red flags suggest that abdominal pain could be serious and needs prompt medical attention.
This guide explains what red flags to watch for, why they matter, and when you should speak to a doctor. The goal is to help you make informed decisions without causing unnecessary worry.
Abdominal pain refers to discomfort anywhere between the chest and the groin. It can come from many organs, including the stomach, intestines, liver, gallbladder, pancreas, kidneys, bladder, and reproductive organs.
Common, usually harmless causes include:
However, abdominal pain that behaves differently than expected—such as being severe, persistent, or associated with other symptoms—can be a sign of something more serious.
A red flag is a warning sign that suggests abdominal pain may be caused by a potentially serious or life‑threatening condition. These signs don't always mean something dangerous is happening, but they do mean you should not ignore the pain.
Red flags are based on patterns seen in medical research and clinical practice and are widely used by doctors to decide when urgent care is needed.
Below are the most important red flags to be aware of. If you notice one or more of these, it is wise to speak to a doctor as soon as possible.
This type of abdominal pain may be associated with conditions such as appendicitis, bowel obstruction, perforation, pancreatitis, or reduced blood flow to the intestines.
Fever combined with abdominal pain may suggest infection or inflammation, such as:
This may indicate bowel obstruction, severe infection, or internal bleeding.
These are important red flags that may indicate bleeding in the digestive tract. Even small amounts of blood should be discussed with a doctor.
Sometimes abdominal pain is not coming from the abdomen at all. Conditions such as heart attack or blood clots can cause pain that feels like it is in the stomach area.
This is especially important if you also have:
When combined with abdominal pain, this can be a red flag for chronic inflammatory disease, infection, or, less commonly, cancer. These symptoms should always be evaluated.
Pain that worsens instead of improving is a sign that the underlying cause may be progressing.
In pregnancy, abdominal pain can sometimes be related to serious conditions such as ectopic pregnancy or complications affecting the mother or baby. These symptoms should be assessed urgently.
This can indicate problems with the liver, gallbladder, or pancreas and should not be ignored.
Extra caution is needed if abdominal pain occurs in:
Symptoms may be less obvious but more serious in these groups.
Abdominal pain is usually not dangerous when it:
Even so, ongoing or recurrent abdominal pain should still be discussed with a healthcare professional.
If you're experiencing symptoms and want to better understand what might be causing your discomfort, Ubie's free AI-powered Abdominal pain symptom checker can help you quickly assess your condition and determine whether you need to seek medical care.
A symptom checker can help you:
It does not replace medical advice but can be a helpful first step.
You should speak to a doctor promptly if:
Seek urgent or emergency care for:
Trust your instincts. If something feels wrong, it is better to get checked.
A red flag for abdominal pain is any sign that suggests the pain may be caused by a serious condition. These include severe or worsening pain, fever, vomiting, blood in stool or vomit, unexplained weight loss, chest symptoms, or pain during pregnancy.
Most abdominal pain is not dangerous, but ignoring red flags can delay important treatment. Using tools like a symptom checker and speaking to a doctor can help you take the right next step.
If abdominal pain could be life‑threatening or serious, do not wait—speak to a doctor or seek urgent medical care.
(References)
* Flapan M, Manganella J, Thode HC, Singer AJ. Acute Abdominal Pain. Emerg Med Clin North Am. 2021 May;39(2):299-307. PMID: 33894760.
* Al-Jabri B, Al-Jabri A, Ghandour Z, Ghandour B, Almufti A, Alzoubi M, Alshami Y, Al-Sayyad N, Abukhalil H. Evaluation of acute abdominal pain in the emergency department: a review article. Ann Med Surg (Lond). 2022 Feb 16;75:103407. PMID: 35222718.
* Macaluso CR, McNamara RM. Acute Abdominal Pain: A Practical Approach. Am Fam Physician. 2018 Mar 15;97(6):369-377. PMID: 29533317.
* Cartwright SL, Mandalia M, Patel R, Khanbhai A, Mistry P; BMJ Best Practice. Assessment of acute abdominal pain in adults. BMJ. 2020 Aug 11;370:m3141. PMID: 32788220.
* Holleran RS, Jørgensen MH, Christensen EF. Risk stratification in patients with acute abdominal pain: systematic review. Scand J Trauma Resusc Emerg Med. 2019 Nov 22;27(1):103. PMID: 31757367.
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