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Published on: 2/27/2026
Abnormal cells usually are not cancer and often reflect your body’s response to irritation, infection, hormonal shifts, aging, immune changes, or exposures; next steps typically include repeat testing or a biopsy to confirm, then monitoring or treatment based on severity such as dysplasia or precancer.
There are several factors to consider, including red flag symptoms that need urgent care and ways to lower risk or even reverse mild changes; see below for complete guidance on tests, treatments, and the key questions to ask your doctor that can shape your next step.
Hearing that you have abnormal cells can feel unsettling. But in many cases, abnormal cells do not mean cancer. Cells in your body are constantly growing, dividing, repairing, and dying. When something disrupts that process, changes can show up on a lab test, biopsy, or screening exam.
Understanding why cells change — and what to do next — can help you respond calmly and confidently.
Your body is made up of trillions of cells. Each one has a specific job:
Cells follow a tightly controlled life cycle. They grow, divide, and eventually die in a predictable pattern. When this process becomes disrupted, abnormal cells can form.
Abnormal cells may:
Not all abnormal cells are dangerous. Many are temporary or reversible.
Abnormal cells develop for a reason. Your body is reacting to something.
Chronic irritation can change how cells behave. Examples include:
When tissue is irritated repeatedly, cells may adapt — and that adaptation can appear "abnormal" under a microscope.
Certain infections can directly affect cells.
For example:
The key word is persistent. Most infections clear, and cells return to normal.
Hormones regulate many types of cells, especially in:
Shifts in hormone levels can temporarily affect how cells grow and divide.
As you age, cells accumulate minor DNA damage over time. Most of the time, your body repairs it. Occasionally, small changes remain.
This is one reason why abnormal cells become more common with age — even in healthy people.
Your immune system constantly monitors and removes abnormal cells. If it becomes weakened or overwhelmed, some abnormal cells may persist longer than usual.
Certain exposures can damage cells:
Repeated exposure increases the likelihood that cells will change.
When a doctor says "abnormal cells," they are usually referring to one of several medical terms:
Most abnormal findings fall into the first three categories — not cancer.
Skin is one of the most common places abnormal cells are detected.
Changes may appear as:
Sun exposure is the leading cause of abnormal skin cells. Some changes are harmless. Others require treatment to prevent progression.
If you've noticed any unusual changes and aren't sure whether they need medical attention, a free Abnormal skin symptom checker can help you assess your symptoms and determine whether you should see a doctor.
If abnormal cells are found, your doctor may recommend:
Sometimes cells look abnormal due to temporary irritation or lab variation. A repeat test confirms whether the change persists.
A small sample of tissue is examined under a microscope for more detail.
Ultrasound, MRI, CT scan, or mammogram may be used to evaluate tissue structure.
Blood tests or genetic testing may provide additional information.
The goal is to determine:
Treatment depends on the location and severity of the abnormal cells.
Possible treatments include:
Many precancerous cell changes are treated successfully before they ever become life-threatening.
While many abnormal cells are not dangerous, certain symptoms require urgent evaluation:
If you experience any of these, speak to a doctor immediately.
Yes — in some cases.
Mild abnormal changes can reverse if the trigger is removed. For example:
However, moderate to severe abnormal cells often require medical treatment.
This is why follow-up appointments matter. Skipping monitoring allows abnormal cells to progress unnoticed.
While you cannot eliminate all risk, you can reduce it:
Your body is remarkably good at maintaining balance — when supported.
It's normal to feel anxious when you hear the word "abnormal."
But remember:
The key is not to ignore findings — but also not to panic.
If you've been told you have abnormal cells:
If your abnormal cells involve the skin and you're noticing concerning changes like new moles, discoloration, or persistent lesions, you can use this free Abnormal skin symptom checker to better understand your symptoms before your appointment.
Most importantly, speak to a doctor about any abnormal cell finding — especially if you have concerning symptoms or if the abnormality is described as moderate, severe, or precancerous. Some conditions can become serious or life-threatening if ignored.
Abnormal cells are your body's signal that something has changed. Sometimes that change is harmless. Sometimes it needs monitoring. And occasionally, it requires treatment.
The good news:
Medical science is highly effective at identifying and managing abnormal cell changes early.
Stay informed. Stay proactive. And when in doubt, speak to a doctor to ensure that anything serious is addressed promptly and safely.
(References)
* Hanahan, D., & Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell, 144(5), 646-674. https://pubmed.ncbi.nlm.nih.gov/21376230/
* Gajewski, T. F., Chen, L., & Fuchs, E. J. (2013). Cancer immune surveillance: from discovery to immunotherapy. Cell, 154(1), 44-55. https://pubmed.ncbi.nlm.nih.gov/23827670/
* Quail, D. F., & Joyce, J. A. (2013). Microenvironmental regulation of tumor progression and metastasis. Cell, 154(6), 1163-1175. https://pubmed.ncbi.nlm.nih.gov/24034994/
* Etzioni, P. D., & Etzioni, R. B. (2016). Early detection of cancer: promises and pitfalls. Nature Reviews Clinical Oncology, 13(5), 346–355. https://pubmed.ncbi.nlm.nih.gov/26620586/
* Sharma, P., & Allison, J. P. (2015). Immune checkpoint therapy: a new paradigm in cancer treatment. Cell, 161(2), 205-214. https://pubmed.ncbi.nlm.nih.gov/25860690/
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