Doctors Note Logo

Published on: 2/27/2026

Abnormal Cells? Why Your Body Is Reacting & Medical Next Steps

Abnormal cells usually are not cancer and often reflect your body’s response to irritation, infection, hormonal shifts, aging, immune changes, or exposures; next steps typically include repeat testing or a biopsy to confirm, then monitoring or treatment based on severity such as dysplasia or precancer.

There are several factors to consider, including red flag symptoms that need urgent care and ways to lower risk or even reverse mild changes; see below for complete guidance on tests, treatments, and the key questions to ask your doctor that can shape your next step.

answer background

Explanation

Abnormal Cells? Why Your Body Is Reacting & Medical Next Steps

Hearing that you have abnormal cells can feel unsettling. But in many cases, abnormal cells do not mean cancer. Cells in your body are constantly growing, dividing, repairing, and dying. When something disrupts that process, changes can show up on a lab test, biopsy, or screening exam.

Understanding why cells change — and what to do next — can help you respond calmly and confidently.


What Are Cells and Why Do They Change?

Your body is made up of trillions of cells. Each one has a specific job:

  • Skin cells protect you.
  • Blood cells carry oxygen and fight infection.
  • Gland cells produce hormones.
  • Organ cells help your heart, lungs, liver, and kidneys function.

Cells follow a tightly controlled life cycle. They grow, divide, and eventually die in a predictable pattern. When this process becomes disrupted, abnormal cells can form.

Abnormal cells may:

  • Look different under a microscope
  • Grow faster than expected
  • Divide irregularly
  • Fail to die when they should

Not all abnormal cells are dangerous. Many are temporary or reversible.


Common Reasons Your Body Develops Abnormal Cells

Abnormal cells develop for a reason. Your body is reacting to something.

1. Inflammation or Irritation

Chronic irritation can change how cells behave. Examples include:

  • Long-term sun exposure (skin cells)
  • Smoking (lung and throat cells)
  • Acid reflux (esophageal cells)
  • Chronic infections

When tissue is irritated repeatedly, cells may adapt — and that adaptation can appear "abnormal" under a microscope.


2. Infections

Certain infections can directly affect cells.

For example:

  • Viral infections can alter cell DNA.
  • Some viruses integrate into cells and change how they grow.
  • Persistent infections may increase the risk of pre-cancerous changes.

The key word is persistent. Most infections clear, and cells return to normal.


3. Hormonal Changes

Hormones regulate many types of cells, especially in:

  • Breast tissue
  • Reproductive organs
  • Thyroid gland

Shifts in hormone levels can temporarily affect how cells grow and divide.


4. Aging

As you age, cells accumulate minor DNA damage over time. Most of the time, your body repairs it. Occasionally, small changes remain.

This is one reason why abnormal cells become more common with age — even in healthy people.


5. Immune System Response

Your immune system constantly monitors and removes abnormal cells. If it becomes weakened or overwhelmed, some abnormal cells may persist longer than usual.


6. Environmental Exposures

Certain exposures can damage cells:

  • Ultraviolet (UV) radiation
  • Tobacco smoke
  • Excessive alcohol
  • Industrial chemicals
  • Air pollution

Repeated exposure increases the likelihood that cells will change.


Types of Abnormal Cell Changes

When a doctor says "abnormal cells," they are usually referring to one of several medical terms:

✅ Dysplasia

  • Cells look abnormal but are not cancer.
  • Often described as mild, moderate, or severe.
  • Can sometimes return to normal on their own.

✅ Atypical Cells

  • Cells don't look typical but are not clearly cancerous.
  • May require monitoring or repeat testing.

✅ Precancerous Cells

  • Abnormal cells that have a higher risk of becoming cancer over time.
  • Treatment may be recommended to prevent progression.

✅ Cancerous Cells

  • Cells that grow uncontrollably.
  • Can invade nearby tissue and spread.

Most abnormal findings fall into the first three categories — not cancer.


Abnormal Skin Cells: What They Mean

Skin is one of the most common places abnormal cells are detected.

Changes may appear as:

  • A new mole
  • A changing mole
  • Rough or scaly patches
  • Non-healing sores
  • Pigment changes

Sun exposure is the leading cause of abnormal skin cells. Some changes are harmless. Others require treatment to prevent progression.

If you've noticed any unusual changes and aren't sure whether they need medical attention, a free Abnormal skin symptom checker can help you assess your symptoms and determine whether you should see a doctor.


How Doctors Evaluate Abnormal Cells

If abnormal cells are found, your doctor may recommend:

🔎 Repeat Testing

Sometimes cells look abnormal due to temporary irritation or lab variation. A repeat test confirms whether the change persists.

🧪 Biopsy

A small sample of tissue is examined under a microscope for more detail.

🧬 Imaging

Ultrasound, MRI, CT scan, or mammogram may be used to evaluate tissue structure.

🧫 Lab Tests

Blood tests or genetic testing may provide additional information.

The goal is to determine:

  • Are the cells stable?
  • Are they progressing?
  • Do they need removal?
  • Can they be monitored safely?

When Abnormal Cells Need Treatment

Treatment depends on the location and severity of the abnormal cells.

Possible treatments include:

  • Monitoring only (watchful waiting)
  • Topical medications
  • Minor surgical removal
  • Laser therapy
  • Freezing (cryotherapy)
  • Prescription medications
  • Radiation or chemotherapy (in confirmed cancers)

Many precancerous cell changes are treated successfully before they ever become life-threatening.


Warning Signs That Should Prompt Immediate Medical Care

While many abnormal cells are not dangerous, certain symptoms require urgent evaluation:

  • Rapidly growing lumps
  • Unexplained bleeding
  • Persistent pain
  • A sore that doesn't heal
  • Sudden weight loss
  • Severe fatigue
  • Difficulty swallowing or breathing
  • Changes in bowel or bladder habits

If you experience any of these, speak to a doctor immediately.


Can Abnormal Cells Go Back to Normal?

Yes — in some cases.

Mild abnormal changes can reverse if the trigger is removed. For example:

  • Quitting smoking
  • Treating infection
  • Reducing sun exposure
  • Managing chronic inflammation

However, moderate to severe abnormal cells often require medical treatment.

This is why follow-up appointments matter. Skipping monitoring allows abnormal cells to progress unnoticed.


How to Lower Your Risk of Abnormal Cells

While you cannot eliminate all risk, you can reduce it:

  • Use sunscreen daily.
  • Avoid tanning beds.
  • Stop smoking.
  • Limit alcohol.
  • Eat a diet rich in vegetables and fiber.
  • Maintain a healthy weight.
  • Stay physically active.
  • Get recommended screenings (Pap tests, mammograms, colonoscopy, skin checks).
  • Treat chronic conditions promptly.

Your body is remarkably good at maintaining balance — when supported.


The Emotional Side of Abnormal Cells

It's normal to feel anxious when you hear the word "abnormal."

But remember:

  • Abnormal does not automatically mean cancer.
  • Many abnormal cells never progress.
  • Modern medicine detects changes earlier than ever.
  • Early detection significantly improves outcomes.

The key is not to ignore findings — but also not to panic.


What To Do Next

If you've been told you have abnormal cells:

  1. Ask what type of abnormality it is.
  2. Ask how severe it is.
  3. Ask whether it requires monitoring or treatment.
  4. Ask about follow-up timing.
  5. Keep your appointments.

If your abnormal cells involve the skin and you're noticing concerning changes like new moles, discoloration, or persistent lesions, you can use this free Abnormal skin symptom checker to better understand your symptoms before your appointment.

Most importantly, speak to a doctor about any abnormal cell finding — especially if you have concerning symptoms or if the abnormality is described as moderate, severe, or precancerous. Some conditions can become serious or life-threatening if ignored.


Final Thoughts

Abnormal cells are your body's signal that something has changed. Sometimes that change is harmless. Sometimes it needs monitoring. And occasionally, it requires treatment.

The good news:
Medical science is highly effective at identifying and managing abnormal cell changes early.

Stay informed. Stay proactive. And when in doubt, speak to a doctor to ensure that anything serious is addressed promptly and safely.

(References)

  • * Hanahan, D., & Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell, 144(5), 646-674. https://pubmed.ncbi.nlm.nih.gov/21376230/

  • * Gajewski, T. F., Chen, L., & Fuchs, E. J. (2013). Cancer immune surveillance: from discovery to immunotherapy. Cell, 154(1), 44-55. https://pubmed.ncbi.nlm.nih.gov/23827670/

  • * Quail, D. F., & Joyce, J. A. (2013). Microenvironmental regulation of tumor progression and metastasis. Cell, 154(6), 1163-1175. https://pubmed.ncbi.nlm.nih.gov/24034994/

  • * Etzioni, P. D., & Etzioni, R. B. (2016). Early detection of cancer: promises and pitfalls. Nature Reviews Clinical Oncology, 13(5), 346–355. https://pubmed.ncbi.nlm.nih.gov/26620586/

  • * Sharma, P., & Allison, J. P. (2015). Immune checkpoint therapy: a new paradigm in cancer treatment. Cell, 161(2), 205-214. https://pubmed.ncbi.nlm.nih.gov/25860690/

Thinking about asking ChatGPT?Ask me instead

Tell your friends about us.

We would love to help them too.

smily Shiba-inu looking

For First Time Users

What is Ubie’s Doctor’s Note?

We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.

Learn more about symptoms

Abnormal skin

Was this page helpful?

Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.