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Published on: 2/23/2026
Adenomyosis is a common reason a uterus appears enlarged or inflamed, caused by endometrial tissue growing into the uterine muscle and triggering bleeding within the wall that leads to heavy, painful periods, pelvic pressure, and sometimes anemia or fertility challenges. Diagnosis relies on history, exam, and imaging such as transvaginal ultrasound or MRI, and treatment ranges from NSAIDs and hormonal options including a hormonal IUD to procedures like uterine artery embolization, ablation, or hysterectomy based on symptoms and pregnancy goals. There are several factors to consider, including red flags and which option fits you best, so see the complete details below to guide your next medical steps.
If you've been told your uterus looks "bulky," "enlarged," or "inflamed," or you're dealing with heavy, painful periods that seem to be getting worse with age, you may be wondering: Is it adenomyosis?
Adenomyosis is a common but often misunderstood condition. It can significantly affect quality of life, yet many women go years without a clear diagnosis. Understanding what adenomyosis is, what symptoms to watch for, and what to do next can help you take informed, confident steps toward better health.
Adenomyosis happens when tissue that normally lines the inside of the uterus (the endometrium) grows into the muscular wall of the uterus (the myometrium).
Each month, this misplaced tissue thickens, breaks down, and bleeds—just like regular uterine lining. But because it's trapped within the muscle wall, it can cause:
Over time, the uterus may become enlarged and tender. Some women describe it as feeling "heavy" or "full" in the lower abdomen.
Adenomyosis is not cancer, but it can be painful and disruptive.
The inflammation comes from repeated monthly bleeding inside the uterine muscle. Unlike normal menstrual blood, this blood cannot exit the body easily. The result can be:
The condition often worsens during the reproductive years because it is influenced by estrogen. Symptoms may improve after menopause when hormone levels decline.
Symptoms vary. Some women have mild issues. Others experience severe pain and heavy bleeding.
Common signs include:
If your periods have become heavier or more painful in your 30s or 40s, adenomyosis may be worth discussing with your doctor.
Adenomyosis is more common in:
However, younger women can develop adenomyosis too.
Symptoms of adenomyosis overlap with several other gynecological conditions. It is often mistaken for:
The key difference is where the abnormal tissue is located. In adenomyosis, the tissue is embedded in the uterine muscle wall. In endometriosis, similar tissue grows outside the uterus.
Because symptoms overlap, imaging is often needed for a clearer diagnosis.
There is no single blood test for adenomyosis.
Doctors typically diagnose it through:
Your doctor will ask about:
The uterus may feel enlarged, soft, or tender.
In the past, adenomyosis was only definitively diagnosed after hysterectomy. Today, imaging technology allows for much earlier and less invasive detection.
If you're unsure whether your symptoms align with this condition, using a free AI-powered Adenomyosis symptom checker can help you assess your risk and prepare informed questions before your doctor's appointment.
Adenomyosis is not life-threatening. However, it can become serious if:
Ignoring severe symptoms is not recommended. Heavy bleeding that soaks through pads or tampons hourly, severe pelvic pain, or signs of anemia (fatigue, dizziness, shortness of breath) should prompt medical attention.
Treatment depends on:
For mild cases:
Hormonal therapy aims to reduce bleeding and suppress abnormal tissue growth.
Options include:
These treatments can reduce symptoms but do not permanently cure adenomyosis.
This minimally invasive procedure reduces blood supply to affected tissue. It may improve symptoms in some women but is not suitable for everyone.
This procedure removes or destroys the uterine lining. It may reduce bleeding but is often less effective if adenomyosis extends deeply into the muscle.
Surgical removal of the uterus is the only definitive cure for adenomyosis.
It is typically considered when:
While effective, hysterectomy is major surgery and requires careful discussion with a gynecologist.
The relationship between adenomyosis and fertility is still being studied.
Some women conceive without difficulty. Others may experience:
If you are trying to conceive and suspect adenomyosis, speak with a reproductive specialist early.
Make an appointment if you experience:
Seek urgent care if you have:
While adenomyosis itself is not cancer, other serious conditions can cause similar symptoms. Always speak to a doctor about symptoms that could be serious or life threatening.
If diagnosed, remember:
Lifestyle adjustments that may help include:
Pain and heavy bleeding are not something you have to "just live with."
Adenomyosis is a common cause of an inflamed, enlarged uterus and heavy, painful periods. It happens when uterine lining tissue grows into the muscular wall of the uterus, leading to swelling and chronic inflammation.
While not life-threatening, it can significantly affect daily life. The good news is that modern imaging makes diagnosis easier than ever, and multiple treatment options exist—from hormonal therapies to surgical solutions.
If your periods are getting worse instead of better, trust your instincts. Take a few minutes to use this free AI-powered Adenomyosis symptom checker to better understand what you're experiencing, then bring those insights to your doctor. Most importantly, speak to a healthcare professional about any persistent, severe, or concerning symptoms.
You deserve answers—and relief.
(References)
* Chapron C, et al. Adenomyosis: A Systematic Review of Diagnosis and Interventions. Front Surg. 2020 Jul 15;7:47. doi: 10.3389/fsurg.2020.00047. PMID: 32766329.
* Struble J, et al. Adenomyosis: An Update on Diagnosis and Treatment. J Clin Med. 2023 Apr 1;12(7):2680. doi: 10.3390/jcm12072680. PMID: 37049877.
* Zervoudis S, et al. Adenomyosis and chronic pelvic pain: a comprehensive review. J Clin Med. 2023 Jan 3;12(1):326. doi: 10.3390/jcm12010326. PMID: 36615174.
* Guo Y, et al. The Role of Inflammation in Adenomyosis Pathogenesis. Front Immunol. 2021 Sep 1;12:735773. doi: 10.3389/fimmu.2021.735773. PMID: 34539851.
* Maia H, et al. Management of adenomyosis: current medical and surgical options. Arch Gynecol Obstet. 2022 Jul;306(1):1-14. doi: 10.1007/s00404-022-06484-z. PMID: 35332309.
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