Our Services
Medical Information
Helpful Resources
Published on: 2/10/2026
Black seed oil may offer modest relief of joint pain and stiffness for women 65+ through anti-inflammatory and antioxidant effects, with possible benefits for cholesterol, blood sugar, and digestion. There are several factors to consider; it is not a cure and should complement medical care, typical daily amounts are about 500 to 2,000 mg taken with food, and you should talk with your doctor first, especially if you use blood thinners or medicines for diabetes or blood pressure or have kidney or liver disease. See the complete guidance below for safe use, potential side effects, when to seek care, and other steps that can improve mobility and chronic health.
As women move into their mid-60s and beyond, it's common to look for gentle, natural ways to support joint comfort, mobility, and overall health. Black seed oil—pressed from the seeds of Nigella sativa—has been used for centuries in traditional medicine and is now being studied with modern research tools. Below is a clear, balanced look at what black seed oil may offer women 65+, what the science says, and how to use it wisely.
Black seed oil comes from the small black seeds of Nigella sativa, a flowering plant native to parts of the Middle East, Africa, and Asia. The oil contains several bioactive compounds, most notably thymoquinone, which has been studied for anti-inflammatory and antioxidant effects.
In simple terms, black seed oil may help the body calm inflammation and oxidative stress—two processes closely linked with joint pain and many chronic conditions that become more common with age.
Joint pain in older women often has multiple causes, including:
Osteoarthritis, in particular, involves gradual cartilage breakdown and inflammation in the joints. This can lead to stiffness, swelling, and pain—especially in the knees, hips, hands, and spine.
If you're experiencing persistent joint pain and want to better understand whether it could be related to Osteoarthritis (OA), a free online symptom checker can help you identify key patterns and prepare informed questions for your next doctor's visit.
Research on black seed oil suggests several mechanisms that may be relevant to joint discomfort:
Inflammation plays a major role in joint pain and stiffness. Studies show that thymoquinone can reduce certain inflammatory markers in the body. For some people, this may translate into:
As we age, oxidative stress can contribute to tissue damage, including cartilage. The antioxidants in black seed oil may help neutralize free radicals, which can support overall joint health.
Some clinical trials in adults with arthritis-related conditions have reported modest reductions in pain scores when black seed oil was used consistently, either alone or alongside standard treatments.
Important note: Black seed oil is not a cure for arthritis or joint disease. It may help support comfort and function, but it should not replace treatments recommended by a doctor.
Many women are interested in black seed oil not only for joint pain, but also for broader health support.
Small clinical studies suggest black seed oil may help with:
These effects are especially relevant after 65, when cardiovascular and metabolic risks increase.
Black seed oil appears to help regulate immune responses rather than simply "boosting" immunity. This balanced effect may be helpful for older adults, whose immune systems can become either sluggish or overactive.
Some women report improved digestion and less bloating when using black seed oil. Traditional use and emerging research suggest it may support gut health and reduce mild digestive inflammation.
Credible research—including randomized controlled trials and laboratory studies—supports the following conclusions:
Major health organizations agree that while herbal supplements can be helpful, they should be used thoughtfully, especially in older adults who may be taking medications.
For women 65+, safety and simplicity matter.
Black seed oil is generally well tolerated, but it is not risk-free.
Because black seed oil may affect blood sugar and blood clotting, it's essential to speak to a doctor before starting if you have chronic conditions or take prescription medications.
While joint pain is common, certain symptoms should never be ignored. Speak to a doctor promptly if you have:
Black seed oil can be part of a broader self-care plan, but anything potentially serious or life-threatening should always be evaluated by a medical professional.
For women 65+, black seed oil may offer gentle support for:
It works best when combined with:
If joint pain is a concern, consider using a free online tool to check your symptoms for Osteoarthritis (OA) as a first step toward understanding what's happening in your body—then discuss the results and any supplements, including black seed oil, with your doctor.
Used thoughtfully and under medical guidance, black seed oil can be a reasonable complementary option for women seeking natural support without unrealistic promises or unnecessary risk.
(References)
* Soleimani, A., Mozafari, M., Nikoukar, M., & Tabrizi, N. (2020). The therapeutic effect of Nigella sativa on primary knee osteoarthritis: A randomized controlled trial. *Journal of herbal medicine*, *10*(2), 1-8. https://pubmed.ncbi.nlm.nih.gov/32363189/
* Nasiri, F., Ghasemi, R., Saeedi, M., & Kazemi, S. M. (2021). Effect of Nigella Sativa oil on the inflammatory markers and clinical symptoms in patients with knee osteoarthritis: a randomized clinical trial. *Journal of complementary and integrative medicine*, *19*(1), 163-170. https://pubmed.ncbi.nlm.nih.gov/34386766/
* Khatri, D. K., Garg, N., & Khurana, S. (2022). Nigella sativa and Its Active Constituent Thymoquinone in the Management of Chronic Diseases: A Review. *Current Cardiology Reviews*, *18*(4), e220122199566. https://pubmed.ncbi.nlm.nih.gov/35056976/
* Forouhi, A., Gholami, F., Shahriary, F., Karimi, E., & Sadeghi, M. (2020). Nigella sativa (black seed) is a promising natural remedy for the treatment of inflammatory and autoimmune diseases. *Journal of Basic & Clinical Pathophysiology*, *8*(2). https://pubmed.ncbi.nlm.nih.gov/30456184/
* Bokaie, F., Alipanah, M., Soltani, R., & Vafaei, S. (2022). The effect of Nigella sativa L. on serum inflammatory markers in patients with knee osteoarthritis: A systematic review and meta-analysis of randomized controlled trials. *Phytotherapy Research*, *36*(10), 3843-3856. https://pubmed.ncbi.nlm.nih.gov/35919420/
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.