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Published on: 2/24/2026

Bleeding Won’t Stop? Why Hemophilia Occurs & Medically Approved Next Steps

Persistent bleeding can signal hemophilia, which occurs when clotting factors are missing or blocked, most often from inherited factor VIII or IX deficiency and sometimes from an immune problem that develops later in life.

There are several factors to consider; see below for key symptoms, risk clues, urgent red flags, and medically approved treatments including factor replacement, newer non factor medicines, and immune therapy for acquired cases, any of which can change your next steps. If bleeding does not stop after 10 to 15 minutes of firm pressure or follows a head injury, seek urgent care now.

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Explanation

Bleeding Won't Stop? Why Hemophilia Occurs & Medically Approved Next Steps

If bleeding won't stop after a minor cut, dental work, or injury, it can be alarming. While many causes of prolonged bleeding are mild, one important condition doctors look for is hemophilia — a rare bleeding disorder that affects the body's ability to form blood clots properly.

Understanding why hemophilia happens and knowing the right next steps can help you respond quickly and safely.


What Is Hemophilia?

Hemophilia is a medical condition where the blood does not clot the way it should. Normally, when you get hurt, your body uses special proteins called clotting factors to stop bleeding. In people with hemophilia, one of these clotting factors is missing or doesn't work correctly.

There are two main inherited types:

  • Hemophilia A – caused by low or missing clotting factor VIII
  • Hemophilia B – caused by low or missing clotting factor IX

Both types lead to similar symptoms, but Hemophilia A is more common.

There is also a rare condition called Acquired Hemophilia, which develops later in life and is not inherited.


Why Does Hemophilia Occur?

1. Inherited Hemophilia (Genetic)

Most cases of hemophilia are inherited. The condition is linked to the X chromosome. Because males have only one X chromosome, they are more likely to have hemophilia if they inherit the affected gene. Females can be carriers and sometimes have mild symptoms.

You may be at higher risk if:

  • There is a family history of hemophilia
  • Male relatives have experienced unexplained bleeding
  • A mother is a known carrier

2. Acquired Hemophilia (Not Inherited)

Acquired Hemophilia is different. It happens when the immune system mistakenly attacks clotting factor VIII. This can occur:

  • After pregnancy
  • With autoimmune disorders
  • With certain cancers
  • With some medications
  • Or without a known cause

Unlike inherited hemophilia, Acquired Hemophilia often affects older adults and people with no personal or family history of bleeding disorders.

If you're experiencing unexplained or prolonged bleeding and have no family history of bleeding disorders, you can use a free Acquired Hemophilia symptom checker to help determine whether your symptoms may be related to this rare condition.


Common Symptoms of Hemophilia

Symptoms can range from mild to severe depending on how much clotting factor is present in the blood.

Mild Hemophilia

  • Bleeding after surgery or dental procedures
  • Easy bruising
  • Nosebleeds that are hard to stop

Moderate Hemophilia

  • Bleeding after minor injuries
  • Occasional spontaneous bleeding
  • Joint pain from internal bleeding

Severe Hemophilia

  • Frequent spontaneous bleeding without injury
  • Deep muscle bleeding
  • Bleeding into joints (knees, ankles, elbows)
  • Blood in urine or stool
  • Prolonged bleeding after small cuts

Bleeding into joints is especially concerning because repeated episodes can cause long-term joint damage if untreated.


When Is Bleeding a Medical Emergency?

Seek urgent medical care if you notice:

  • Bleeding that will not stop after 10–15 minutes of firm pressure
  • Severe headache after a head injury
  • Vomiting or confusion after trauma
  • Sudden severe joint swelling and pain
  • Large, unexplained bruises
  • Heavy bleeding after childbirth or surgery

Internal bleeding is not always visible, so unexplained pain, swelling, or weakness should never be ignored.

If bleeding is severe or life-threatening, call emergency services immediately.


How Doctors Diagnose Hemophilia

If hemophilia is suspected, a doctor will order blood tests that measure:

  • Clotting factor levels
  • Clotting time
  • Presence of factor inhibitors (in Acquired Hemophilia)

These tests clearly show whether factor VIII or IX levels are low.

In inherited hemophilia, testing is often done in childhood, especially if there is family history. Acquired Hemophilia is usually diagnosed later in life, often after unexpected bleeding.


Medically Approved Treatments for Hemophilia

Modern treatment has greatly improved outcomes. With proper care, many people with hemophilia live full, active lives.

1. Clotting Factor Replacement Therapy

This is the main treatment for inherited hemophilia. It involves:

  • Infusing missing clotting factor VIII or IX into the bloodstream
  • Preventive (prophylactic) treatment in severe cases
  • On-demand treatment for bleeding episodes

Replacement therapy can be given at home once patients are trained.

2. Non-Factor Therapies

Newer medications help the body clot more effectively without replacing factor directly. These are often used in Hemophilia A.

3. Treatment for Acquired Hemophilia

Treatment usually involves:

  • Medications to control active bleeding
  • Drugs that suppress the immune system to stop it from attacking clotting factors

Because Acquired Hemophilia can be serious, early treatment is critical.


Lifestyle Considerations for People With Hemophilia

Living with hemophilia requires some adjustments, but it does not mean living in fear.

Helpful steps include:

  • Avoiding high-impact contact sports
  • Using protective gear during physical activity
  • Maintaining a healthy weight to protect joints
  • Practicing good dental care to reduce the need for procedures
  • Informing all healthcare providers about the condition

Many people with hemophilia work, exercise, travel, and raise families successfully with proper medical care.


Can Hemophilia Be Prevented?

Inherited hemophilia cannot be prevented, but genetic counseling can help families understand their risk.

Acquired Hemophilia cannot always be predicted, but early recognition of symptoms improves outcomes significantly.


Why Early Diagnosis Matters

Without treatment, hemophilia can lead to:

  • Chronic joint damage
  • Internal organ bleeding
  • Severe anemia
  • Life-threatening hemorrhage

However, with early diagnosis and modern therapy, complications are far less common than in the past.

Today, life expectancy for many people with hemophilia approaches that of the general population, especially when treatment begins early.


What Should You Do If You're Concerned?

If you or a loved one experiences unusual or prolonged bleeding:

  1. Do not ignore repeated symptoms.
  2. Document when bleeding occurs and how long it lasts.
  3. Ask your doctor for clotting tests if symptoms continue.
  4. Seek emergency care if bleeding is severe or uncontrolled.

If symptoms are new, unexplained, or occurring in adulthood without family history, using a free online tool to check your symptoms for Acquired Hemophilia can help you understand whether you should seek urgent medical evaluation.


The Bottom Line

Hemophilia is a serious but manageable bleeding disorder. It occurs when the body lacks important clotting factors, either due to inherited genetics or an immune system problem in Acquired Hemophilia.

Key takeaways:

  • Persistent or unusual bleeding should never be ignored.
  • Early testing can confirm or rule out hemophilia.
  • Effective, medically approved treatments are available.
  • Most people with proper care live full and active lives.

If you suspect hemophilia — inherited or acquired — speak to a doctor promptly, especially if bleeding is heavy, sudden, or life-threatening. Quick medical attention can prevent complications and protect your long-term health.

Bleeding that won't stop is your body's way of signaling that something needs attention. Listening to that signal — calmly and promptly — is the smartest next step.

(References)

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  • * Ma A, Moores M, Ragni MV. Current and future treatment options for patients with hemophilia. Blood Adv. 2021 Apr 22;5(8):2268-2281. doi: 10.1182/bloodadvances.2020002047. PMID: 33945890; PMCID: PMC8086082.

  • * Lillo E, Ruz-Barría S, Contreras V, Castro V, Varas-Godoy M, Valdés-Gallegos V. Hemophilia: Current Genetic Diagnosis and New Therapeutic Targets. Cells. 2022 Aug 4;11(15):2400. doi: 10.3390/cells11152400. PMID: 35955685; PMCID: PMC9367469.

  • * Srivastava A, Santagostino E, Dougall A, Kitchen S, Sutherland M, Pipe SW, Carcao M, Mahlangu J, Ragni MV, Windyga J, Llinas A, Goddard NJ, Mohan R, Poonnoose PM, Chalmers E, Salazar E, Horowitz MS, Chuansumrit A, Kandula V, Batt R, Krishnan S, Soucie JM, Bussell J, Hoots WK; WFH Guidelines for the Management of Hemophilia Panel. WFH Guidelines for the Management of Hemophilia, 3rd edition. Haemophilia. 2020 Aug;26 Suppl 6:1-158. doi: 10.1111/hae.14046. PMID: 36319139.

  • * Ronsoni M, Cavallaro S, Boffi M, Mancuso ME, Peyvandi F. Emerging Therapies in Hemophilia: Advances and Challenges. J Clin Med. 2023 Aug 24;12(17):5490. doi: 10.3390/jcm12175490. PMID: 37624794; PMCID: PMC10488669.

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