Acquired Hemophilia Quiz

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Bruise easily

Bleeding/bruising in the joints

Rashes

Purplish rash

Bleeding nose

Redness of the skin

Black stools

Blood in vomit

Blood in urine

Joint pain or stiffness

Bright red vomit

Severe headaches

Not seeing your symptoms? No worries!

What is Acquired Hemophilia?

Acquired hemophilia is a rare autoimmune disorder causing bleeding tendencies due to the development of antibodies against clotting factors.

Typical Symptoms of Acquired Hemophilia

Diagnostic Questions for Acquired Hemophilia

Your doctor may ask these questions to check for this disease:

  • Have you noticed any purple marks or spots on your skin?
  • Have you had black, shiny stools?
  • Have you noticed any blood in your stool?
  • Do you bruise or bleed easily?
  • Have you ever been diagnosed with a connective tissue, autoimmune, or rheumatic disease?

Treatment of Acquired Hemophilia

Treatment focuses on managing bleeding episodes and addressing the underlying cause. Treatment options may include immune therapy to suppress the abnormal antibodies, desmopressin for mild cases, and factor replacement therapies.

Reviewed By:

Kaito Nakamura, MD

Kaito Nakamura, MD (Rheumatology)

Dr. Nakamura is a rheumatologist who has practiced in the Ota Nishinouchi Hospital attached to Ota General Hospital, National Health Insurance Matsudo City Hospital, Chiba University Hospital, and the National Health Insurance Asahi Central Hospital.

Unnati Patel, MD, MSc

Unnati Patel, MD, MSc (Family Medicine)

Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.

From our team of 50+ doctors

Content updated on Jan 23, 2025

Following the Medical Content Editorial Policy

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How Ubie Can Help You

With a free 3-min Acquired Hemophilia quiz, powered by Ubie's AI and doctors, find possible causes of your symptoms.

This questionnaire is customized to your situation and symptoms, including the following personal information:

  • Biological Sex - helps us provide relevant suggestions for male vs. female conditions.

  • Age - adjusts our guidance based on any age-related health factors.

  • History - considers past illnesses, surgeries, family history, and lifestyle choices.

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Symptoms Related to Acquired Hemophilia

Diseases Related to Acquired Hemophilia

FAQs

Q.

Bleeding Won’t Stop? Why Hemophilia Occurs & Medically Approved Next Steps

A.

Persistent bleeding can signal hemophilia, which occurs when clotting factors are missing or blocked, most often from inherited factor VIII or IX deficiency and sometimes from an immune problem that develops later in life. There are several factors to consider; see below for key symptoms, risk clues, urgent red flags, and medically approved treatments including factor replacement, newer non factor medicines, and immune therapy for acquired cases, any of which can change your next steps. If bleeding does not stop after 10 to 15 minutes of firm pressure or follows a head injury, seek urgent care now.

References:

* Arai M. Hemophilia: a review of current knowledge and management. J Blood Med. 2023 Apr 5;14:263-275. doi: 10.2147/JBM.S397063. PMID: 37021577; PMCID: PMC10087790.

* Ma A, Moores M, Ragni MV. Current and future treatment options for patients with hemophilia. Blood Adv. 2021 Apr 22;5(8):2268-2281. doi: 10.1182/bloodadvances.2020002047. PMID: 33945890; PMCID: PMC8086082.

* Lillo E, Ruz-Barría S, Contreras V, Castro V, Varas-Godoy M, Valdés-Gallegos V. Hemophilia: Current Genetic Diagnosis and New Therapeutic Targets. Cells. 2022 Aug 4;11(15):2400. doi: 10.3390/cells11152400. PMID: 35955685; PMCID: PMC9367469.

* Srivastava A, Santagostino E, Dougall A, Kitchen S, Sutherland M, Pipe SW, Carcao M, Mahlangu J, Ragni MV, Windyga J, Llinas A, Goddard NJ, Mohan R, Poonnoose PM, Chalmers E, Salazar E, Horowitz MS, Chuansumrit A, Kandula V, Batt R, Krishnan S, Soucie JM, Bussell J, Hoots WK; WFH Guidelines for the Management of Hemophilia Panel. WFH Guidelines for the Management of Hemophilia, 3rd edition. Haemophilia. 2020 Aug;26 Suppl 6:1-158. doi: 10.1111/hae.14046. PMID: 36319139.

* Ronsoni M, Cavallaro S, Boffi M, Mancuso ME, Peyvandi F. Emerging Therapies in Hemophilia: Advances and Challenges. J Clin Med. 2023 Aug 24;12(17):5490. doi: 10.3390/jcm12175490. PMID: 37624794; PMCID: PMC10488669.

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Maxwell J. Nanes, DO

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Waukesha Memorial Hospital, Waukesha Wisconsin, USA

Caroline M. Doan, DO

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Charles Carlson, DO, MS

Charles Carlson, DO, MS

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U.S. Department of Veterans Affairs

Dale Mueller, MD

Dale Mueller, MD

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Link to full study:

https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1

References