Our Services
Medical Information
Helpful Resources
Published on: 1/27/2026
Ulcerative colitis does not have a permanent cure and does not usually go away on its own, but many people achieve long periods of remission with the right treatment and regular follow-up. Removing the colon and rectum can technically eliminate the disease, yet it is major surgery and typically reserved for cases not controlled by medications. There are several factors to consider, including how remission is measured, why maintenance therapy matters, and what can trigger flares; see the complete answer below to understand more and choose your next steps.
Ulcerative colitis is a chronic inflammatory bowel disease (IBD) that affects the lining of the large intestine (colon) and rectum. A common and very understandable question from people who are newly diagnosed—or worried they might be—is: can ulcerative colitis go away?
The short answer is no, ulcerative colitis does not currently have a permanent cure, but that answer needs important context. Many people with ulcerative colitis can live long, full lives with few or even no symptoms for long periods of time. Understanding what “going away” really means in medical terms can help reduce fear and support better decision-making.
Below is a clear, honest explanation based on widely accepted medical knowledge and clinical guidelines.
When people ask if ulcerative colitis can go away, they may mean different things, such as:
In medical terms, ulcerative colitis is considered a lifelong condition, but it often goes through cycles:
Remission can last months or even years. During this time, many people feel “normal” and may forget they have the disease. However, remission is not the same as a cure.
Yes. Ulcerative colitis can go into remission, and for many people, this is the primary goal of treatment.
Remission can mean:
There are different levels of remission:
With proper treatment and monitoring, many people achieve long-term remission.
Ulcerative colitis does not usually go away without treatment. While symptoms may temporarily improve, ongoing inflammation can still be present under the surface. Left untreated, this inflammation can lead to complications over time.
That said, the course of ulcerative colitis varies:
Because symptoms do not always match disease activity, it’s important not to assume the condition has gone away just because you feel better.
Treatment aims to control inflammation, reduce symptoms, and prevent complications. Your doctor tailors treatment based on how severe your ulcerative colitis is and how your body responds.
Common treatment approaches include:
For many people, staying on maintenance therapy—even during remission—is what keeps ulcerative colitis from returning.
Surgery is the only option that can technically eliminate ulcerative colitis, because the disease only affects the colon and rectum.
This involves removing the colon and rectum, which:
Surgery is not the first choice for most people. It is usually considered when:
Many people manage ulcerative colitis successfully without ever needing surgery.
Medical experts classify ulcerative colitis as chronic because:
This does not mean constant illness. Think of ulcerative colitis more like a condition that needs long-term management, similar to asthma or diabetes.
Several factors influence how often ulcerative colitis flares:
Working closely with a healthcare provider significantly improves long-term outcomes.
Some symptoms of ulcerative colitis overlap with other conditions, such as:
If you have ongoing digestive symptoms and no clear diagnosis, you might consider doing a free, online symptom check for Ulcerative Colitis. This can help you organize your symptoms and decide whether medical evaluation is needed.
A diagnosis of ulcerative colitis can feel overwhelming, but many people lead active, fulfilling lives. Key strategies include:
Importantly, emotional health matters. Anxiety and fear are common early on, but knowledge and a care plan often bring confidence.
You should speak to a doctor if you experience:
Some complications of ulcerative colitis can be serious or life-threatening if ignored. Prompt medical care is essential.
While ulcerative colitis is a lifelong condition, it does not define you. With the right support and medical guidance, many people spend far more time living their lives than thinking about their diagnosis. If you have concerns or symptoms, consider starting with a symptom review and always speak to a doctor about anything that feels serious or life-threatening.
(References)
* Bressler B, Marshall JK, Bernstein CN. Ulcerative Colitis: Natural History and Long-Term Outcome. Gastroenterology. 2024 May;166(6):1005-1020. doi: 10.1053/j.gastro.2023.12.016. Epub 2023 Dec 15. PMID: 38104473.
* Kim ES, Kim KO, Jang YS, et al. Defining Remission in Ulcerative Colitis: A Systematic Review. Gut Liver. 2023 Mar 15;17(2):226-242. doi: 10.5009/gnl22013. PMID: 36914562; PMCID: PMC10006733.
* Magro F, Barreto L, Ferreira S, et al. Treat-to-Target in Ulcerative Colitis: Current Status and Future Directions. J Crohns Colitis. 2022 Dec 15;16(12):1811-1823. doi: 10.1093/ecco-jcc/jjac094. PMID: 35704179.
* Sandborn WJ. Prognosis of Ulcerative Colitis. J Crohns Colitis. 2022 Dec 15;16(Suppl 2):S161-S167. doi: 10.1093/ecco-jcc/jjac178. PMID: 36520779.
* Deng B, Liu H, Li X, et al. Long-term outcomes in patients with ulcerative colitis under different treatment strategies: a systematic review and meta-analysis. Ann Palliat Med. 2022 Feb;11(2):630-644. doi: 10.21037/apm-21-3965. PMID: 35193498.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.