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Published on: 11/17/2025

Can chronic sleep deprivation affect brain structure or function?

Yes, chronic sleep deprivation can change how the brain works and even affect its structure.

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Explanation

Chronic sleep deprivation can have significant effects on the brain's structure and function. According to research, it can change the way genes in the brain work, which might affect brain health over time.

  • Gene Expression: Long-term lack of sleep can change the activity of certain genes in the brain. These changes can impact how the brain functions and responds to stress.

  • Brain Function: Sleep deprivation affects the brain's ability to process information and can lead to problems with memory and decision-making.

  • Neuronal Plasticity: This is the brain's ability to change and adapt. Lack of sleep can reduce this ability, making it harder for the brain to learn new things or recover from injury.

In summary, not getting enough sleep can make it harder for the brain to work well and might even change the way it looks and functions. If you are experiencing mental health concerns, please visit 988lifeline.org for support.

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