Is It Colitis? Why Your Colon Is Inflamed & Medical Next Steps

If you've been dealing with ongoing diarrhea, stomach pain, or blood in your stool, you may be wondering: Is it colitis?

Colitis simply means inflammation of the colon (large intestine). It is not one single disease. Instead, it's a term doctors use when the lining of your colon becomes irritated, swollen, or damaged.

Some causes of colitis are mild and temporary. Others can be chronic (long-term) and require ongoing medical care. Understanding what might be happening — and what to do next — can help you take the right steps without unnecessary panic.

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What Is Colitis?

The colon plays a key role in:

• Absorbing water
• Processing waste
• Supporting healthy gut bacteria

When the colon becomes inflamed, it can't function normally. That inflammation can cause symptoms that range from uncomfortable to serious.

Common symptoms of colitis include:

• Persistent diarrhea
• Blood or mucus in stool
• Abdominal pain or cramping
• Urgency to have a bowel movement
• Fatigue
• Fever (in some cases)
• Unexplained weight loss

If you are experiencing severe pain, high fever, heavy bleeding, dehydration, or weakness, seek medical care immediately. Some forms of colitis can become life-threatening without treatment.

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What Causes Colitis?

There are several different types of colitis. Identifying the cause is essential because treatment depends on the type.

1. Ulcerative Colitis (UC)

Ulcerative colitis is a chronic autoimmune disease. It happens when the immune system mistakenly attacks the lining of the colon.

Key features:

• Ongoing inflammation
• Ulcers (open sores) in the colon
• Symptoms that flare and improve over time
• Most commonly starts in young adulthood, but can occur at any age

Ulcerative colitis is a form of inflammatory bowel disease (IBD). It requires long-term medical management.

If your symptoms are ongoing, you can use a free AI-powered symptom checker for Ulcerative Colitis to help you understand whether your symptoms align with this condition and what questions to bring to your doctor.

This is not a diagnosis — but it can help guide your next steps before speaking to a doctor.

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2. Infectious Colitis

This type of colitis is caused by:

• Bacteria (such as Salmonella, E. coli, or C. difficile)
• Viruses
• Parasites

It often develops suddenly and may include:

• Fever
• Severe diarrhea
• Recent travel or food exposure
• Recent antibiotic use

Infectious colitis can range from mild to severe. Some infections resolve on their own, while others require antibiotics or urgent care.

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3. Ischemic Colitis

Ischemic colitis occurs when blood flow to part of the colon is reduced.

It is more common in:

• Adults over 60
• People with heart disease
• People with clotting disorders

Symptoms often include:

• Sudden abdominal pain
• Bloody stools

This condition can be serious and requires prompt medical evaluation.

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4. Microscopic Colitis

Microscopic colitis cannot be seen during a regular colonoscopy without biopsy.

It typically causes:

• Chronic watery diarrhea
• Little to no bleeding
• Normal-looking colon on visual exam

It is more common in middle-aged and older adults.

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5. Allergic or Drug-Induced Colitis

Some medications can inflame the colon, including:

• NSAIDs (like ibuprofen)
• Certain antibiotics
• Some cancer treatments

Food allergies (more common in infants) may also trigger colitis.

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How Doctors Diagnose Colitis

If colitis is suspected, your doctor may recommend:

Medical History & Physical Exam

• Symptom duration
• Travel history
• Medication review
• Family history of IBD

Stool Tests

These help detect:

• Bacterial infections
• Parasites
• C. difficile
• Blood or inflammation markers

Blood Tests

Doctors may check for:

• Anemia
• Signs of infection
• Inflammatory markers

Colonoscopy

A colonoscopy allows direct visualization of the colon and biopsy of tissue.

Biopsy is often necessary to:

• Confirm ulcerative colitis
• Identify microscopic colitis
• Rule out other conditions

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When Is Colitis Serious?

Colitis can become serious if it leads to:

• Severe dehydration
• Heavy rectal bleeding
• Toxic megacolon (dangerous colon swelling)
• Perforation (tear in the colon wall)
• Increased colon cancer risk (with long-term ulcerative colitis)

You should seek urgent care if you experience:

• Continuous heavy bleeding
• Severe abdominal pain
• High fever
• Signs of dehydration (dizziness, confusion, low urine output)
• Rapid heart rate

These symptoms require immediate medical attention.

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Treatment Options for Colitis

Treatment depends entirely on the cause.

For Infectious Colitis:

• Hydration
• Electrolyte replacement
• Antibiotics (if bacterial)
• Avoid anti-diarrheal medications unless advised

For Ulcerative Colitis:

• Anti-inflammatory medications (5-ASA drugs)
• Corticosteroids (short-term)
• Immune system suppressors
• Biologic therapies
• In some cases, surgery

The goal is to:

• Reduce inflammation
• Achieve remission
• Prevent complications

For Ischemic Colitis:

• Hospital monitoring
• IV fluids
• Treatment of underlying vascular issues
• Surgery in severe cases

For Microscopic Colitis:

• Medication adjustments
• Anti-inflammatory treatments
• Dietary modifications

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Lifestyle Changes That May Help

While lifestyle changes alone cannot cure most types of colitis, they can help manage symptoms:

• Stay hydrated
• Eat smaller, more frequent meals
• Avoid trigger foods (spicy, high-fat, high-fiber during flares)
• Limit alcohol
• Stop smoking (especially important for Crohn's disease)
• Manage stress

If you suspect ulcerative colitis, tracking your symptoms can be helpful before your appointment. Before seeing a doctor, you can check your symptoms using Ubie's free Ulcerative Colitis symptom checker to help organize your concerns and prepare meaningful questions for your visit.

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Could It Be Something Else?

Not all digestive symptoms are colitis. Other possibilities include:

• Irritable bowel syndrome (IBS)
• Diverticulitis
• Colon cancer
• Celiac disease
• Hemorrhoids (for bleeding)

This is why proper medical evaluation is important. Guessing or self-diagnosing can delay appropriate treatment.

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When to Speak to a Doctor

You should schedule a medical appointment if you have:

• Diarrhea lasting more than a few days
• Blood in your stool
• Ongoing abdominal pain
• Unexplained weight loss
• Persistent fatigue
• Family history of inflammatory bowel disease

Even if symptoms seem mild, chronic inflammation should not be ignored.

If anything feels severe, rapidly worsening, or life-threatening — seek emergency medical care immediately.

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The Bottom Line

Colitis means inflammation of the colon — but the reason behind that inflammation matters.

Some causes are temporary and treatable. Others, like ulcerative colitis, require long-term care and monitoring. The key is identifying the type of colitis early so you can get the right treatment.

If you are unsure whether your symptoms match ulcerative colitis, you can use a free AI symptom checker for Ulcerative Colitis to better understand your risk before speaking with a healthcare professional.

Most importantly: do not ignore persistent digestive symptoms. Early diagnosis leads to better outcomes, fewer complications, and more effective treatment.

If you are experiencing severe pain, heavy bleeding, dehydration, or high fever, speak to a doctor or seek emergency care immediately.

Your colon health matters — and help is available.