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Published on: 1/29/2026

Crampy abdominal pain that won’t go away — IBD or IBS?

Persistent crampy abdominal pain can stem from IBS or IBD; IBS is a functional issue without inflammation that often eases after bowel movements or with diet changes, while IBD is inflammatory, may cause nighttime or more localized pain, and usually needs medical treatment. Red flags like blood in the stool, chronic diarrhea, weight loss, fever, anemia, or pain that wakes you should prompt urgent medical care. There are several factors to consider; see below for key details on symptoms, tests, and when to seek help, which could change your next steps.

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Explanation

Crampy abdominal pain that won't go away — IBD or IBS?

Abdominal pain is one of the most common reasons people seek medical advice. When the pain is crampy and keeps coming back—or never seems to fully resolve—it's natural to wonder what's going on. Two conditions often mentioned are Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD). They sound similar, but they are very different problems with different levels of seriousness and treatment needs.

Below is a clear, practical guide to help you understand the differences, what symptoms matter most, and when it's important to speak to a doctor.


Understanding crampy abdominal pain

Crampy abdominal pain usually comes from the intestines contracting or spasming. It can feel:

  • Tight or squeezing
  • Dull with waves of sharper pain
  • Better or worse after eating or using the bathroom

Occasional cramping can happen to anyone. Pain that won't go away, interferes with daily life, or comes with other symptoms deserves attention.


IBS and IBD: similar names, very different conditions

Irritable Bowel Syndrome (IBS)

IBS is a functional digestive disorder. This means the gut looks normal on tests, but it doesn't work as smoothly as it should.

Key points about IBS:

  • It does not cause inflammation or permanent damage
  • Symptoms can be uncomfortable but are not life-threatening
  • Symptoms often come and go over time

IBS is common and can affect people of all ages.


Inflammatory Bowel Disease (IBD)

IBD is an autoimmune condition that causes chronic inflammation in the digestive tract. The two main types are:

  • Crohn's disease
  • Ulcerative colitis

Key points about IBD:

  • It does cause visible inflammation and tissue damage
  • Symptoms tend to worsen over time without treatment
  • It can lead to serious complications if untreated

IBD is less common than IBS but more serious.


How abdominal pain feels in IBS vs IBD

While both conditions can cause abdominal pain, the pattern and context often differ.

Abdominal pain in IBS

  • Crampy or spasmodic
  • Often relieved after a bowel movement
  • Linked to stress, certain foods, or hormonal changes
  • Pain may move around the abdomen

The pain is real, but it usually does not wake people from sleep.


Abdominal pain in IBD

  • Persistent and sometimes severe
  • May be localized (often lower right or left side)
  • Can occur at night
  • Often accompanied by other systemic symptoms

This pain reflects ongoing inflammation rather than just muscle spasms.


Other symptoms that help tell the difference

Common IBS symptoms

  • Bloating and gas
  • Diarrhea, constipation, or alternating between both
  • Mucus in the stool
  • Feeling of incomplete bowel movements

IBS symptoms often improve with diet changes and stress management.


Common IBD symptoms

  • Chronic diarrhea
  • Blood or pus in the stool
  • Unexplained weight loss
  • Fatigue
  • Fever
  • Reduced appetite

These symptoms suggest inflammation and should not be ignored.


Red flags that point away from IBS

Doctors pay close attention to certain warning signs. These are not typical of IBS and may suggest IBD or another serious condition.

Red flags include:

  • Blood in the stool
  • Abdominal pain that wakes you at night
  • Ongoing diarrhea for weeks
  • Unintentional weight loss
  • Persistent fever
  • Anemia (low iron)
  • Family history of IBD or colon cancer

If you have any of these, it's important to speak to a doctor promptly.


Why IBS does not turn into IBD

A common concern is whether IBS can "become" IBD. Based on current medical understanding:

  • IBS does not progress into IBD
  • They are separate conditions with different causes
  • Having IBS does not increase your risk of developing IBD

However, symptoms can overlap, which is why proper evaluation matters.


How doctors tell IBS and IBD apart

There is no single test for IBS. Diagnosis is based on symptoms and ruling out other conditions.

Tests commonly used when IBD is suspected:

  • Blood tests (looking for inflammation or anemia)
  • Stool tests (checking for inflammation or infection)
  • Colonoscopy or imaging studies

These tests help confirm whether inflammation is present.


Managing abdominal pain in IBS

IBS treatment focuses on symptom control and quality of life.

Common approaches include:

  • Adjusting diet (such as reducing trigger foods)
  • Managing stress and anxiety
  • Medications to reduce cramping or regulate bowel movements
  • Improving sleep and physical activity

Many people with IBS find that understanding their triggers significantly reduces abdominal pain.


Treating abdominal pain in IBD

IBD requires medical treatment to control inflammation.

Treatment may include:

  • Anti-inflammatory medications
  • Immune-modulating drugs
  • Biologic therapies
  • Nutritional support

Early treatment can reduce complications and protect long-term digestive health.


When abdominal pain should never be ignored

While most abdominal pain is not an emergency, some situations require urgent care.

Seek immediate medical help if abdominal pain is accompanied by:

  • Severe or worsening pain
  • High fever
  • Vomiting blood
  • Black, tarry stools
  • Signs of dehydration
  • Sudden abdominal swelling

These could indicate a life-threatening condition.


Checking your symptoms thoughtfully

If you're experiencing persistent crampy pain and want to better understand what might be causing it, using a free Abdominal pain symptom checker can help you organize your symptoms and determine whether you should seek medical care—though it should never replace a conversation with your doctor.


The bottom line

  • IBS causes chronic abdominal pain without inflammation or damage
  • IBD causes abdominal pain due to ongoing inflammation and requires medical treatment
  • Red flag symptoms are key to telling the difference
  • Persistent or worsening abdominal pain should always be discussed with a healthcare professional

If your abdominal pain won't go away, affects your daily life, or comes with concerning symptoms, speak to a doctor. Early evaluation helps rule out serious conditions and ensures you get the right care at the right time.

(References)

  • * pubmed.ncbi.nlm.nih.gov/36737227/

  • * pubmed.ncbi.nlm.nih.gov/32415516/

  • * pubmed.ncbi.nlm.nih.gov/34217316/

  • * pubmed.ncbi.nlm.nih.gov/33139268/

  • * pubmed.ncbi.nlm.nih.gov/36384024/

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