What are the side effects of kampo medicine?

Reviewed by Yoshinori Abe, MD

Internal Medicine

Kampo medicine is a traditional Japanese herbal therapy used to treat a wide range of conditions, but like other herbal and traditional medicines, it can cause side effects. Common adverse reactions may include gastrointestinal issues, skin rashes, liver dysfunction, and interstitial pneumonia, though effects vary based on the specific formulation, dosage, and individual patient factors such as age, existing conditions, and other medications being taken.

Because symptoms can overlap with many other health issues—and because side effects from Kampo may mimic unrelated conditions—it's important to identify what's really behind how you're feeling before assuming a cause. Taking a free, instant, online symptom check can help you better understand your symptoms, identify possible conditions, and guide your next steps with clarity and confidence.

Reviewed for medical accuracy: 07/14/2026

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Explanation

Common Side Effects

Kampo medicine can cause a range of side effects, which may include:

Gastrointestinal Issues: Some individuals may experience nausea, vomiting, diarrhea, or abdominal discomfort after taking Kampo formulations. These symptoms can arise from the herbal ingredients used in the remedies.
Allergic Reactions: As with any herbal medicine, there is a risk of allergic reactions. Symptoms may include skin rashes, itching, or respiratory issues in sensitive individuals.
Drowsiness or Fatigue: Certain Kampo formulations may have sedative effects, leading to drowsiness or fatigue. This can be particularly concerning for individuals who need to remain alert, such as those driving or operating machinery.

Specific Herb-Related Risks

Some specific herbs commonly used in Kampo medicine may have their own side effects or interactions:

Licorice Root (Glycyrrhiza uralensis): This herb is often included in Kampo formulations but can lead to elevated blood pressure and low potassium levels if consumed in large amounts or over extended periods.
Ginseng: While often used for its energizing properties, ginseng can cause insomnia, headaches, or gastrointestinal upset in some individuals.
Other Herbs: Various other herbs used in Kampo may have specific side effects or contraindications, particularly for individuals with certain health conditions or those taking other medications.

Interactions with Conventional Medications

Kampo medicine can interact with conventional medications, potentially altering their effectiveness or increasing the risk of side effects. It is essential for individuals to inform their healthcare providers about any Kampo remedies they are using, especially if they are on prescription medications.

Need for Professional Guidance

Due to the potential for side effects and interactions, it is advisable for individuals considering Kampo medicine to consult with a qualified healthcare provider or a practitioner experienced in traditional medicine. If you're experiencing concerning symptoms and want to understand what might be causing them, try our free AI symptom checker to help guide your conversation with a healthcare professional. This ensures that the chosen remedies are appropriate for their specific health needs and conditions.

(References)

Yu F, Takahashi T, Moriya J, Kawaura K, Yamakawa J, Kusaka K, Itoh T, Morimoto S, Yamaguchi N, Kanda T. Traditional Chinese medicine and Kampo: a review from the distant past for the future. J Int Med Res. 2006 May-Jun;34(3):231-9. doi: 10.1177/147323000603400301. PMID: 16866016.
Dai Z, Liao X, Wieland LS, Hu J, Wang Y, Kim TH, Liu JP, Zhan S, Robinson N. Cochrane systematic reviews on traditional Chinese medicine: What matters-the quantity or quality of evidence? Phytomedicine. 2022 Apr;98:153921. doi: 10.1016/j.phymed.2021.153921. Epub 2022 Jan 10. PMID: 35104758; PMCID: PMC9741948.

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