Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Kent C Doan, MD (Orthopedics)
Dr Doan Graduated from the University of Missouri Kansas City School of Medicine and completed residency training in Orthopedic Surgery at the University of Colorado. He completed additional fellowship training in Orthopedic Sports Medicine at the prestigious Steadman Clinic and Steadman Philippon Research Institute in Vail, Colorado. He is a practicing Orthopedic Surgeon who specializes in complex and revision knee and shoulder surgery at the Kansas City Orthopedic Institute. He also holds an assistant professorship at the University of Kansas City.
Tomohiro Hamahata, MD (Orthopedics)
Dr. Hamahata graduated from the Jikei University of Medical Science. After working at Asanokawa General Hospital and Kosei Chuo Hospital, he joined the Department of Orthopedics at Asakusa Hospital in April 2021, specializing in general orthopedics and joint replacement surgery.
Content updated on Jan 29, 2025
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Leg cramps are episodes of sudden pain in the muscles of the leg caused by an involuntary contracting (shortening) of the leg muscle.
Seek professional care if you experience any of the following symptoms
Generally, Calf cramp (Charley Horse) can be related to:
Leg cramps are episodes of sudden pain in leg muscles caused by involuntary contractions (shortening) of the leg muscle. Most leg cramps happen in the calf muscles and, less commonly, in the feet and thighs.
Tetany is a condition involving involuntary muscle contractions and overly stimulated peripheral nerves. It is caused by electrolyte imbalances, most often low blood calcium levels.
Diabetic neuropathy is a kind of nerve damage that can happen in people with long-term diabetes. High blood sugar can harm nerves all over the body, mainly in the legs and feet.
Muscle Cramps of All 4 Limbs
Sometimes, Calf cramp (Charley Horse) may be related to these serious diseases:
This is a life-threatening emergency where the person's body temperature is dangerously high and they display neurological abnormalities. This occurs when the body fails to regulate its temperature properly. It can be caused by the surrounding environment (heat, moisture) or internal factors (dehydration, strenuous exercise).
Your doctor may ask these questions to check for this symptom:
We would love to help them too.
Q.
Why Do I Get Leg Cramps When I Stretch in Bed?
A.
Leg cramps during stretching in bed, often referred to as nocturnal leg cramps, can occur due to several factors, including muscle fatigue, dehydration, electrolyte imbalances, and certain medical conditions. Understanding these causes can help in managing and preventing cramps.
References:
Allen RE, Kirby KA. Nocturnal leg cramps. Am Fam Physician. 2012 Aug 15;86(4):350-5. PMID: 22963024.
Brown TM. Sleep-Related Leg Cramps: A Review and Suggestions for Future Research. Sleep Med Clin. 2015 Sep;10(3):385-92, xvi. doi: 10.1016/j.jsmc.2015.05.002. Epub 2015 Jun 14. PMID: 26329449.
Monderer RS, Wu WP, Thorpy MJ. Nocturnal leg cramps. Curr Neurol Neurosci Rep. 2010 Jan;10(1):53-9. doi: 10.1007/s11910-009-0079-5. PMID: 20425227.
Grandner MA, Winkelman JW. Nocturnal leg cramps: Prevalence and associations with demographics, sleep disturbance symptoms, medical conditions, and cardiometabolic risk factors. PLoS One. 2017 Jun 6;12(6):e0178465. doi: 10.1371/journal.pone.0178465. PMID: 28586374; PMCID: PMC5460850.
Q.
What Are the Side Effects of Kampo Medicine?
A.
Kampo medicine, a traditional Japanese form of herbal medicine, can have side effects, similar to other forms of herbal and traditional medicine. While many people use Kampo for its therapeutic benefits, it is important to be aware of potential adverse effects, which can vary depending on the specific formulation and individual patient factors.
References:
Yu F, Takahashi T, Moriya J, Kawaura K, Yamakawa J, Kusaka K, Itoh T, Morimoto S, Yamaguchi N, Kanda T. Traditional Chinese medicine and Kampo: a review from the distant past for the future. J Int Med Res. 2006 May-Jun;34(3):231-9. doi: 10.1177/147323000603400301. PMID: 16866016.
Dai Z, Liao X, Wieland LS, Hu J, Wang Y, Kim TH, Liu JP, Zhan S, Robinson N. Cochrane systematic reviews on traditional Chinese medicine: What matters-the quantity or quality of evidence? Phytomedicine. 2022 Apr;98:153921. doi: 10.1016/j.phymed.2021.153921. Epub 2022 Jan 10. PMID: 35104758; PMCID: PMC9741948.
Q.
What Is the Best Drink to Prevent Muscle Cramps? Are Sports Drinks Effective for This?
A.
To prevent muscle cramps, the best drinks are those that help maintain hydration and replenish electrolytes. Sports drinks can be effective for this purpose, especially during prolonged exercise or in hot conditions, as they contain essential electrolytes like sodium and potassium. However, they also may contain quite a bit of extra sugar and calories as well.
References:
Earp JE, Stearns RL, Stranieri A, Agostinucci J, Lepley AS, Matson T, Ward-Ritacco CL. Electrolyte beverage consumption alters electrically induced cramping threshold. Muscle Nerve. 2019 Nov;60(5):598-603. doi: 10.1002/mus.26650. Epub 2019 Aug 12. PMID: 31350753.
Jung AP, Bishop PA, Al-Nawwas A, Dale RB. Influence of Hydration and Electrolyte Supplementation on Incidence and Time to Onset of Exercise-Associated Muscle Cramps. J Athl Train. 2005 Jun;40(2):71-75. PMID: 15970952; PMCID: PMC1150229.
Hooper Marosek SE, Antharam V, Dowlatshahi K. Quantitative Analysis of the Acetic Acid Content in Substances Used by Athletes for the Possible Prevention and Alleviation of Exercise-Associated Muscle Cramps. J Strength Cond Res. 2020 Jun;34(6):1539-1546. doi: 10.1519/JSC.0000000000003595. PMID: 32459412.
Lau WY, Kato H, Nosaka K. Effect of oral rehydration solution versus spring water intake during exercise in the heat on muscle cramp susceptibility of young men. J Int Soc Sports Nutr. 2021 Mar 15;18(1):22. doi: 10.1186/s12970-021-00414-8. PMID: 33722257; PMCID: PMC7962362.
Q.
What Are Some Home Remedies to Stop Leg Cramps Immediately?
A.
If you experience leg cramps, there are several effective home remedies you can try to relieve the discomfort immediately. These remedies can help relax the muscles and alleviate the cramping sensation.
References:
Riley JD, Antony SJ. Leg cramps: differential diagnosis and management. Am Fam Physician. 1995 Nov 1;52(6):1794-8. PMID: 7484689.
Allen RE, Kirby KA. Nocturnal leg cramps. Am Fam Physician. 2012 Aug 15;86(4):350-5. PMID: 22963024.
Mitsikostas, D. D., Thomas, A. M., & Gatzonis, S. D. (2010). The pathophysiology of medication overuse headache: The ‘neurochemical’ hypothesis revisited. ](https://doi.org/10.1212/WNL.0b013e3181d0ccca)[_Neurology, 74_](https://doi.org/10.1212/WNL.0b013e3181d0ccca)[(5), 398–399.
Q.
What Are the Causes of Leg Cramps at Night?
A.
Leg cramps at night, also known as nocturnal leg cramps, can be caused by a variety of factors, including muscle fatigue, dehydration, electrolyte imbalances, and certain medical conditions. Understanding these causes can help in managing and preventing these painful episodes.
References:
Hallegraeff J, de Greef M, Krijnen W, van der Schans C. Criteria in diagnosing nocturnal leg cramps: a systematic review. BMC Fam Pract. 2017 Feb 28;18(1):29. doi: 10.1186/s12875-017-0600-x. PMID: 28241802; PMCID: PMC5330021.
Monderer RS, Wu WP, Thorpy MJ. Nocturnal leg cramps. Curr Neurol Neurosci Rep. 2010 Jan;10(1):53-9. doi: 10.1007/s11910-009-0079-5. PMID: 20425227.
Allen RE, Kirby KA. Nocturnal leg cramps. Am Fam Physician. 2012 Aug 15;86(4):350-5. PMID: 22963024.
Charley Horse - WebMD
https://www.webmd.com/pain-management/muscle-spasms-cramps-charley-horseReviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Kent C Doan, MD (Orthopedics)
Dr Doan Graduated from the University of Missouri Kansas City School of Medicine and completed residency training in Orthopedic Surgery at the University of Colorado. He completed additional fellowship training in Orthopedic Sports Medicine at the prestigious Steadman Clinic and Steadman Philippon Research Institute in Vail, Colorado. He is a practicing Orthopedic Surgeon who specializes in complex and revision knee and shoulder surgery at the Kansas City Orthopedic Institute. He also holds an assistant professorship at the University of Kansas City.
Tomohiro Hamahata, MD (Orthopedics)
Dr. Hamahata graduated from the Jikei University of Medical Science. After working at Asanokawa General Hospital and Kosei Chuo Hospital, he joined the Department of Orthopedics at Asakusa Hospital in April 2021, specializing in general orthopedics and joint replacement surgery.
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