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Published on: 5/6/2025

What Are the Risk Factors for Developing an Ectopic Pregnancy?

Some factors increase the risk of an ectopic pregnancy, including past pelvic infections, previous surgeries or ectopic pregnancies, and sometimes methods to help with fertility or smoking.

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Explanation

An ectopic pregnancy happens when a fertilized egg grows outside of the main part of the uterus, often in a fallopian tube. One major risk factor is having a past pelvic infection, like from chlamydia or gonorrhea, because these infections can cause scarring in your tubes. If you have had a previous ectopic pregnancy or surgery on your fallopian tubes, your risk may be higher, as these issues can change how the egg moves through the tube. Sometimes, treatments that help with fertility can increase the chance of an ectopic pregnancy. Other factors, such as smoking, can also raise the risk because smoking might affect the way the tube works. These factors can make it harder for the egg to move smoothly into the womb for a normal pregnancy. If you have any concerns or think you might be at risk, talking with a healthcare provider can help you better understand your chances and how to stay as healthy as possible.

(References)

  • Ankum WM, Mol BW, Van der Veen F, Bossuyt PM. Risk factors for ectopic pregnancy: a meta-analysis. Fertil Steril. 1996 Jun;65(6):1093-9. PMID: 8641479.

  • Bouyer J, Coste J, Shojaei T, Pouly JL, Fernandez H, Gerbaud L, Job-Spira N. Risk factors for ectopic pregnancy: a comprehensive analysis based on a large case-control, population-based study in France. Am J Epidemiol. 2003 Feb 1;157(3):185-94. doi: 10.1093/aje/kwf190. PMID: 12543617.

  • Karaer A, Avsar FA, Batioglu S. Risk factors for ectopic pregnancy: a case-control study. Aust N Z J Obstet Gynaecol. 2006 Dec;46(6):521-7. doi: 10.1111/j.1479-828X.2006.00653.x. PMID: 17116058.

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