Published on: 5/30/2025
What are the most effective medicines for treating period cramps?
Naproxen and ibuprofen are effective medicines for treating period cramps by reducing menstrual prostaglandins. Another over-the-counter option is acetaminophen or paracetamol, which can also help relieve pain.
Explanation
Period cramps, also known as dysmenorrhea, can be very painful for many people. Naproxen is effective in treating period cramps. It works by reducing the levels of prostaglandins, which are chemicals in the body that cause the uterus to contract and lead to pain during menstruation. Ibuprofen is another treatment that works similarly to treat period cramps. Another over-the-counter option is acetaminophen or paracetamol, which can also help relieve pain.
How Naproxen and Ibuprofen Work:
- Naproxen and ibuprofen are two types of nonsteroidal anti-inflammatory drugs (NSAIDs).
- They help lower the production of prostaglandins, which are higher during menstruation and cause cramps.
Overall, naproxen, ibuprofen, acetaminophen and paracetamol are well-studied and commonly used options for managing period cramps, making it easier for those affected to go about their daily activities with less discomfort. If these over-the-counter pain relief methods do not alleviate the pain, a healthcare provider can offer personalized medical advice including other possible treatment options.
(References)
- Daniels SE, Paredes-Diaz A, An R, Centofanti R, & Tajaddini A. (2019). a double-blind, randomized, single-dose, crossover study. Current medical research and opinion, 31397597.
- Chan WY, Fuchs F, & Powell AM. (1983). Effects of naproxen sodium on menstrual prostaglandins .... Obstetrics and gynecology, 6571974.
- Christelle K, Norhayati MN, & Jaafar SH. (2022). Interventions to prevent or treat heavy menstrual bleeding .... The Cochrane database of systematic reviews, 36017945.
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