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Published on: 1/21/2026

If meetings knock you out, it’s not the meeting.

There are several factors to consider, from sleep deprivation and poor sleep habits to sleep apnea, medication effects, depression or anxiety, narcolepsy, and serious liver-related causes such as hepatic encephalopathy. See below for key red flags, when to seek urgent care, and practical next steps including tracking symptoms, reviewing medications, and getting sleep studies or liver testing with treatments that can restore alertness.

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Explanation

If Meetings Knock You Out, It's Not the Meeting

Falling asleep in meetings can feel embarrassing, but it's rarely about boredom or lack of professionalism. When you nod off in mid-discussion, it may be your body or brain signaling an underlying issue. Below, we explore common and serious causes—ranging from simple sleep debt to liver-related brain changes—and guide you on next steps.


Common Reasons for Falling Asleep in Meetings

  • Poor Sleep Hygiene
    • Irregular sleep schedule, screens before bed or caffeine late in the day can fragment rest.
    • Try keeping consistent bedtimes, a dark, cool room and avoiding screens an hour before sleep.

  • Sleep Deprivation
    • Chronic sleep debt accumulates quickly. If you average less than 7 hours per night, your brain struggles to stay alert.
    • Aim for 7–9 hours nightly; short naps (20–30 minutes) can help without spoiling nighttime rest.

  • Obstructive Sleep Apnea (OSA)
    • Interrupted breathing leads to repeated micro-awakenings.
    • Common signs: loud snoring, gasping at night, morning headaches, daytime drowsiness.

  • Medications & Substances
    • Antihistamines, some antidepressants or pain medications can cause sedation.
    • Alcohol or recreational drugs also impact sleep architecture.

  • Mood Disorders
    • Depression and anxiety often disrupt sleep and energy levels.
    • You might feel drowsy or mentally "checked out" during the day.


When Daytime Sleepiness Signals Something Serious

If basic fixes—better sleep habits, cutting back on sedatives—don't help, consider medical causes:

  • Narcolepsy
    • Irresistible daytime sleep attacks, often with sudden muscle weakness (cataplexy).
    • Diagnosis: sleep studies and clinical evaluation.

  • Chronic Liver Disease & Hepatic Encephalopathy
    • In advanced liver disease, toxins (like ammonia) build up and affect brain function.
    • Symptoms include confusion, sleep/wake inversion, a "flapping" tremor of the hands (asterixis) and, yes, excessive daytime sleepiness—even in the middle of a meeting.


Understanding Hepatic Encephalopathy

Hepatic encephalopathy (HE) occurs when a diseased liver fails to clear toxins, leading to brain dysfunction. Key points from leading studies and guidelines:

  • Natural History and Prognostic Indicators
    (D'Amico G, Garcia-Tsao G & Pagliaro L. 2006)
    • Patients with cirrhosis who develop HE have a variable outlook; recurrence is common.
    • Factors like severity of liver scarring, blood chemistry and presence of other complications (e.g., variceal bleeding) shape survival.

  • 2014 Practice Guidelines
    (Vilstrup H, Amodio P, Bajaj J, et al. 2014)
    • Grading HE ranges from mild changes in sleep pattern to deep coma.
    • Management includes identifying and treating triggers (e.g., dehydration, infections) plus specific therapies like lactulose and rifaximin.

  • Assessing Liver Fibrosis
    (Castera L. 2011)
    • Non-invasive tools (ultrasound elastography) estimate liver stiffness, reducing need for biopsy.
    • Early detection of advanced fibrosis or cirrhosis allows timely treatment to prevent HE.


How to Tell If HE Might Be at Play

Watch for a combination of:

  • Mental fogginess or confusion
  • Shifts in sleep pattern—nodding off at odd times, reversed day/night cycle
  • Mood changes: irritability or lethargy
  • Tremors or unsteady handwriting

If you have known liver disease or risk factors (heavy alcohol use, viral hepatitis, fatty liver disease), stay especially alert.


Practical Steps to Take

  1. Track Your Sleep & Symptoms
    • Keep a diary: sleep times, naps, meeting nod-offs, mood and diet.
    • Note any patterns or triggers (certain foods, stress, missed meds).

  2. Check Your Symptoms with a Free AI-Powered Tool
    • If you're experiencing persistent daytime sleepiness or other concerning patterns, Ubie's free sleep disorder symptom checker can help identify potential causes and guide you toward the right next steps.

  3. Review Medications & Substances
    • List all prescription, over-the-counter drugs and supplements.
    • Discuss with your doctor potential sedating effects or interactions.

  4. Get Basic Tests
    • Blood work: liver enzymes (AST/ALT), bilirubin, ammonia level if HE is suspected.
    • Imaging or elastography to assess liver fibrosis per Castera's recommendations.

  5. Specialist Referral
    • Sleep study for suspected apnea or narcolepsy.
    • Hepatology consultation if liver tests or imaging show significant disease.


Treatment Pathways

  • Sleep Apnea: CPAP machines, lifestyle changes (weight loss, positional therapy).
  • Narcolepsy: Stimulants, scheduled naps and behavioral strategies.
  • Depression/Anxiety: Counseling, cognitive behavioral therapy (CBT), appropriate medications.
  • Hepatic Encephalopathy
    • Lactulose: reduces ammonia absorption in the gut.
    • Rifaximin: antibiotic that decreases ammonia-producing bacteria.
    • Addressing triggers: treat infections, manage electrolytes, ensure adequate nutrition.

When to Seek Urgent Help

Call emergency services or go to your nearest emergency department if you or someone else experiences:

  • Sudden confusion, inability to recognize people or places
  • Severe drowsiness that you can't "wake up" from
  • Asterixis (flapping tremor of the hands)
  • Jaundice combined with mental changes
  • Seizures or loss of consciousness

These signs may indicate severe HE or other life-threatening conditions.


Final Thoughts

Sleeping through a meeting isn't just poor etiquette—it can be your body telling you something's off. From simple lifestyle tweaks to screening for sleep disorders or checking liver health, there are clear steps you can take:

  • Improve sleep hygiene and track patterns
  • Use Ubie's free AI sleep disorder symptom checker to understand what might be causing your daytime drowsiness
  • Discuss any concerning symptoms—especially if you have liver risk factors—with your doctor promptly

If you notice persistent daytime sleepiness, confusion or other alarming signs, speak to a doctor. Early diagnosis and treatment can restore your energy, sharpen your focus and keep you safe—both in meetings and beyond.

(References)

  • D'Amico G, Garcia-Tsao G, & Pagliaro L. (2006). Natural history and prognostic indicators of survival in cirr… J Hepatol, 16310515.

  • Vilstrup H, Amodio P, Bajaj J, Cordoba J, Ferenci P, Mullen KD, et al. (2014). Hepatic encephalopathy in chronic liver disease: 2014 practice guidel… J Hepatol, 24837833.

  • Castera L. (2011). Non-invasive assessment of liver fibrosis: hepatic elastographe… J Hepatol, 21785243.

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