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Published on: 2/24/2026

Farxiga Side Effects? The Reality & Medically Approved Next Steps

Farxiga side effects range from common issues like genital yeast infections, urinary tract infections, and increased urination or dehydration to rare but serious problems such as ketoacidosis, acute kidney injury, and a very rare genital infection; knowing when symptoms are urgent is critical.

There are several factors to consider, including age, kidney function, diuretic use, and other diabetes medications; see below for medically approved next steps like not stopping the drug suddenly, staying hydrated, tracking symptoms, getting regular labs, and exactly when to seek urgent care.

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Explanation

Farxiga Side Effects? The Reality & Medically Approved Next Steps

If you've been prescribed Farxiga, you may be wondering about possible side effects and what they really mean for your health. That's a smart question.

Farxiga (generic name: dapagliflozin) is an FDA‑approved medication used to treat:

  • Type 2 diabetes
  • Heart failure
  • Chronic kidney disease

It belongs to a class of drugs called SGLT2 inhibitors. These medications work by helping your kidneys remove excess sugar from your blood through urine.

For many people, Farxiga is effective and well tolerated. But like all medications, it comes with potential side effects — some mild, some more serious. Below is a clear, medically grounded breakdown so you can understand what's normal, what's uncommon, and what needs urgent attention.


Common Farxiga Side Effects

These are the most frequently reported side effects. They are generally mild and manageable.

1. Urinary Tract Infections (UTIs)

Because Farxiga increases sugar in the urine, bacteria can grow more easily in the urinary tract.

Symptoms may include:

  • Burning with urination
  • Frequent urination
  • Cloudy or strong-smelling urine
  • Pelvic discomfort

Most UTIs are treatable with antibiotics. However, if you develop:

  • Fever
  • Back pain
  • Nausea or vomiting

Seek medical care promptly, as this may signal a kidney infection.


2. Genital Yeast Infections

This is one of the most common side effects, especially in women but also in men.

Symptoms may include:

  • Itching
  • Redness
  • Swelling
  • Discharge

These infections are usually mild and treatable with antifungal medications. If infections are recurring, your doctor may reassess whether Farxiga is the right option for you.


3. Increased Urination

Since Farxiga removes excess sugar through urine, you may notice:

  • More frequent trips to the bathroom
  • Increased thirst

This is expected. However, excessive thirst, dizziness, or weakness could signal dehydration.


4. Dehydration and Low Blood Pressure

Farxiga causes fluid loss, which can lead to:

  • Dizziness
  • Lightheadedness
  • Fainting

This risk is higher in:

  • Older adults
  • People taking diuretics ("water pills")
  • Those with low blood pressure

Staying hydrated is important. If you feel faint or dizzy regularly, speak to your doctor.


Less Common but Serious Farxiga Side Effects

These side effects are rare but important to understand.

1. Diabetic Ketoacidosis (DKA)

Although more common in type 1 diabetes, DKA has been reported in people with type 2 diabetes taking Farxiga.

What makes this unusual is that blood sugar may not be extremely high.

Warning signs include:

  • Nausea or vomiting
  • Abdominal pain
  • Fatigue
  • Rapid breathing
  • Confusion

This is a medical emergency. Seek immediate care if you experience these symptoms.


2. Acute Kidney Injury

Farxiga affects kidney function, and while it is protective in many chronic kidney disease patients, rare cases of acute kidney injury have occurred.

Symptoms may include:

  • Decreased urination
  • Swelling in legs or feet
  • Fatigue

Routine blood tests help monitor kidney function. This is why follow-up labs are important.


3. Fournier's Gangrene (Very Rare)

This is an extremely rare but serious infection of the genital and perineal area.

Symptoms include:

  • Severe pain
  • Redness or swelling in the genital area
  • Fever
  • Feeling very ill

Though rare, this requires emergency treatment. Do not delay care if these symptoms occur.


4. Low Blood Sugar (When Combined with Other Diabetes Medications)

Farxiga alone does not usually cause hypoglycemia. However, when combined with:

  • Insulin
  • Sulfonylureas

Low blood sugar becomes more likely.

Symptoms include:

  • Shaking
  • Sweating
  • Confusion
  • Rapid heartbeat

Your doctor may adjust other medications to reduce this risk.


Who Is at Higher Risk for Farxiga Side Effects?

You may need closer monitoring if you:

  • Are over age 65
  • Have kidney disease
  • Take diuretics
  • Have a history of frequent UTIs
  • Have low blood pressure
  • Have a history of ketoacidosis

Always disclose your full medical history to your provider.


The Benefits of Farxiga

It's important not to focus only on risks.

Farxiga has been shown in major clinical trials to:

  • Lower blood sugar in type 2 diabetes
  • Reduce hospitalization for heart failure
  • Slow progression of chronic kidney disease
  • Reduce cardiovascular risk in certain patients

For many patients, the benefits outweigh the risks — especially when monitored appropriately.


Medically Approved Next Steps If You're Concerned

If you're experiencing symptoms or are worried about side effects, here's what to do:

✅ 1. Do Not Stop Farxiga Suddenly Without Guidance

Stopping abruptly may worsen blood sugar or heart failure symptoms.


✅ 2. Monitor Your Symptoms Carefully

Keep track of:

  • Urinary symptoms
  • Dizziness
  • Nausea
  • Changes in urination
  • Blood sugar readings

Patterns help your doctor make informed decisions.


✅ 3. Stay Hydrated

Drink adequate fluids unless your doctor has placed you on fluid restriction.


✅ 4. Get Regular Lab Work

Your doctor may monitor:

  • Kidney function (creatinine, eGFR)
  • Electrolytes
  • Blood sugar
  • A1C

Routine testing reduces risk of serious complications.


✅ 5. Consider Evaluating Your Diabetes Symptoms

If you're experiencing concerning symptoms and want to better understand whether they might be related to Diabetes Mellitus itself or your medication, a free AI-powered symptom checker can help you identify patterns and prepare informed questions for your next doctor's visit.


When to Seek Immediate Medical Care

Call your doctor or seek emergency care if you experience:

  • Severe abdominal pain
  • Persistent vomiting
  • Confusion
  • Difficulty breathing
  • Severe genital pain or swelling
  • Signs of severe dehydration
  • Symptoms of ketoacidosis

These situations can become life‑threatening if ignored.


How to Talk to Your Doctor About Farxiga

If you're unsure whether Farxiga is right for you, consider asking:

  • Are my benefits outweighing my risks?
  • Are my kidney labs stable?
  • Should my dose be adjusted?
  • Are there alternative medications for my condition?

Shared decision-making is the goal.


The Bottom Line on Farxiga Side Effects

Farxiga is a widely used and clinically proven medication for diabetes, heart failure, and kidney disease. Most side effects are mild and manageable, such as yeast infections or increased urination.

However, rare but serious complications — including ketoacidosis and severe infections — require awareness and prompt medical care.

The key points to remember:

  • Most people tolerate Farxiga well
  • Stay hydrated
  • Monitor symptoms
  • Keep regular lab appointments
  • Never ignore severe or unusual symptoms

If anything feels concerning, especially symptoms that could be serious or life‑threatening, speak to a doctor immediately. Early medical evaluation can prevent complications and protect your health.

Medication decisions should always be made with a qualified healthcare professional who understands your full medical history.

Your health deserves careful, informed attention — not fear, but not avoidance either.

(References)

  • * Jankovic M, Del Prato S. Dapagliflozin: A Review in Type 2 Diabetes and Heart Failure with Reduced Ejection Fraction. Drugs. 2021 Oct;81(15):1783-1798. PMID: 34508688.

  • * Patel DK, Prawiro D, Khakhkhar V, Shah N, Bhattacharya PT, Agrawal M. Side effects of SGLT2 inhibitors and their management: A comprehensive review. Diabetes Metab Syndr. 2022 Mar-Apr;16(3):102434. PMID: 35193026.

  • * Duan Z, Zheng C, Li Z, Huang S, Zhu T. Adverse effects of SGLT2 inhibitors: an updated review of current evidence. Expert Opin Drug Saf. 2022 May;21(5):609-623. PMID: 35142142.

  • * Verma S, Manda V. Dapagliflozin in patients with type 2 diabetes and chronic kidney disease: An updated safety and efficacy review. Curr Med Res Opin. 2022 Feb;38(2):207-219. PMID: 34914101.

  • * Koyani H, Kothari M. Safety of dapagliflozin across the spectrum of cardio-renal-metabolic diseases: a narrative review. Cardiovasc Diabetol. 2022 Jul 23;21(1):144. PMID: 35870956.

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