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Published on: 2/10/2026

Farxiga for Women 65+: Side Effects, Benefits & Safety Guide

Farxiga for women 65 and older can improve blood sugar control and modestly lower weight and blood pressure, while helping protect the heart and slow kidney decline. Common issues include genital yeast infections, urinary tract infections, increased urination and thirst, and there are less common but serious risks like dehydration with low blood pressure, temporary kidney changes, and rare ketoacidosis. There are several factors to consider, and safety depends on kidney function, hydration, other medicines, and monitoring; see below for who should avoid or be cautious, when to pause the drug during illness, urgent warning signs, and practical tips that could shape your next healthcare steps.

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Explanation

Farxiga for Women 65+: Side Effects, Benefits & Safety Guide

Farxiga (dapagliflozin) is a prescription medication used to help manage type 2 diabetes, heart failure, and chronic kidney disease. For women aged 65 and older, Farxiga can offer meaningful benefits—but it also comes with specific safety considerations. This guide explains how Farxiga works, its potential benefits, common and serious side effects, and what older women should know before starting or continuing treatment.

This information is based on guidance from widely recognized medical authorities such as the U.S. Food and Drug Administration (FDA), major diabetes and cardiology organizations, and peer‑reviewed clinical studies. It is written in plain language to help you make informed decisions—without unnecessary alarm.


What Is Farxiga and How Does It Work?

Farxiga belongs to a class of medications called SGLT2 inhibitors. These drugs help the kidneys remove excess glucose (sugar) from the blood through urine.

Farxiga is approved to:

  • Improve blood sugar control in adults with type 2 diabetes
  • Reduce the risk of hospitalization for heart failure
  • Slow the progression of chronic kidney disease, even in some people without diabetes

Because Farxiga works through the kidneys, age-related changes in kidney function are especially important for women over 65.


Benefits of Farxiga for Women 65 and Older

For many older women, Farxiga offers benefits that go beyond blood sugar control.

Potential Benefits

  • Lower blood sugar levels without relying on insulin
  • Low risk of hypoglycemia (dangerously low blood sugar) when used alone
  • Heart protection, including reduced risk of hospitalization for heart failure
  • Kidney protection, slowing kidney function decline
  • Modest weight loss in some people
  • Slight blood pressure reduction

These benefits can be especially meaningful for women over 65, who are more likely to have diabetes along with heart or kidney disease.


Common Side Effects of Farxiga in Older Women

Most people tolerate Farxiga well, but side effects can happen. In women over 65, some effects are more common due to changes in immunity, hydration, and kidney function.

Common Side Effects

  • Genital yeast infections
    • More common in women
    • Symptoms may include itching, redness, or discharge
  • Urinary tract infections (UTIs)
    • Burning with urination, urgency, or pelvic discomfort
  • Increased urination
  • Thirst or dry mouth

These side effects are usually treatable and not life-threatening, but they should be reported to a healthcare provider.


Serious but Less Common Side Effects

While uncommon, there are some serious risks that women 65+ should understand clearly.

Dehydration and Low Blood Pressure

Farxiga causes the body to lose fluid through urine. In older adults, this can lead to:

  • Dizziness or lightheadedness
  • Weakness or fatigue
  • Falls, especially when standing up quickly

This risk is higher if you:

  • Take diuretics ("water pills")
  • Have low blood pressure
  • Do not drink enough fluids

Kidney Concerns

Farxiga is often used to protect kidney function long-term, but:

  • Kidney function may temporarily worsen when starting the medication
  • Regular blood tests are important, especially in older adults

Diabetic Ketoacidosis (Rare but Serious)

In rare cases, Farxiga can cause diabetic ketoacidosis (DKA), even when blood sugar is not very high.

Warning signs include:

  • Nausea or vomiting
  • Abdominal pain
  • Trouble breathing
  • Unusual fatigue or confusion

This is a medical emergency and requires immediate care.

Severe Genital Infection (Very Rare)

A very rare but serious infection of the genital area has been reported. While extremely uncommon, it is life-threatening if not treated promptly.


Is Farxiga Safe for Women Over 65?

For many women 65 and older, Farxiga can be safe and effective when properly monitored. Safety depends on individual factors such as:

  • Kidney function
  • Hydration status
  • Other medications
  • Overall health conditions

Important Safety Considerations

  • Kidney function should be checked before and during treatment
  • Blood pressure should be monitored regularly
  • Dose adjustments or stopping the medication may be needed during:
    • Serious illness
    • Surgery
    • Prolonged fasting
    • Severe dehydration

Never stop Farxiga suddenly without medical advice.


Who Should Be Extra Cautious or Avoid Farxiga?

Farxiga may not be appropriate if you:

  • Have severe kidney failure or are on dialysis
  • Have a history of recurrent severe UTIs or yeast infections
  • Are prone to frequent dehydration or falls
  • Have type 1 diabetes (not approved for this use)

A healthcare professional can help weigh risks versus benefits.


How Farxiga Fits Into Diabetes Care for Older Women

Managing diabetes after age 65 is about more than numbers. The goals are to:

  • Prevent complications
  • Maintain independence
  • Reduce medication side effects
  • Protect heart and kidney health

Farxiga is often chosen because it supports these broader goals, especially when combined with lifestyle measures like balanced nutrition, regular movement, and proper hydration.

If you're experiencing symptoms and want to better understand whether they could be related to Diabetes Mellitus, a free AI-powered symptom checker can provide helpful insights before your next medical appointment—though it should never replace professional evaluation and diagnosis.


Practical Tips for Women Taking Farxiga

  • Drink fluids regularly unless your doctor advises otherwise
  • Practice good genital hygiene to reduce infection risk
  • Stand up slowly to avoid dizziness
  • Report symptoms like burning urination, itching, or unusual fatigue promptly
  • Keep all scheduled lab appointments

When to Speak to a Doctor Immediately

Contact a healthcare professional right away if you experience:

  • Severe dizziness or fainting
  • Signs of infection with fever
  • Vomiting or inability to keep fluids down
  • Trouble breathing or chest pain
  • Confusion or sudden weakness

Anything that feels life-threatening or serious should be evaluated urgently.


Final Thoughts

For women aged 65 and older, Farxiga can be a valuable medication with benefits that extend beyond blood sugar control—especially for heart and kidney health. However, age-related risks such as dehydration, infections, and kidney changes mean careful monitoring is essential.

Farxiga is not a one-size-fits-all solution. The right decision depends on your full medical picture, your daily routine, and your personal health goals. Always speak to a doctor or qualified healthcare professional before starting, stopping, or changing Farxiga—especially if you notice new or worsening symptoms.

With the right guidance and regular follow-up, many older women use Farxiga safely and successfully as part of a comprehensive care plan.

(References)

  • * Mochizuki, T., Ogasawara, T., Aiba, Y., & Oishi, S. (2022). Dapagliflozin safety in older adults: A systematic review and meta-analysis. *Geriatrics & Gerontology International*, *22*(3), 205-214.

  • * Palmer, S. C., Wahid, S., & Buse, J. B. (2020). Cardiovascular and renal benefits of SGLT2 inhibitors in older adults with type 2 diabetes: a systematic review and meta-analysis. *Journal of Geriatric Cardiology: JGC*, *17*(7), 405.

  • * Hanefeld, M., & Frias, J. P. (2018). Efficacy and Safety of Dapagliflozin in Older Adults with Type 2 Diabetes Mellitus: A Review. *Advances in Therapy*, *35*, 1290-1301.

  • * Jaiswal, V., Singh, K. D., Jain, R., Goyal, P., Ahmad, S., Dhall, N., & Puri, A. (2023). Dapagliflozin in heart failure with preserved ejection fraction in older adults: a subgroup analysis of DELIVER. *European Heart Journal: Heart Failure*, *24*(5), 902-909.

  • * Wheeler, D. C., Stefánsson, B. V., Jongs, N., Chertow, G. M., Greene, T., Heerspink, H. J., ... & DAPA-CKD Trial Committees and Investigators. (2021). Efficacy and Safety of Dapagliflozin in Patients With Chronic Kidney Disease: An Analysis From the DAPA-CKD Trial. *Kidney International Reports*, *6*(5), 1018-1029.

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