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Published on: 2/10/2026
Farxiga for women 65 and older can improve blood sugar control and modestly lower weight and blood pressure, while helping protect the heart and slow kidney decline. Common issues include genital yeast infections, urinary tract infections, increased urination and thirst, and there are less common but serious risks like dehydration with low blood pressure, temporary kidney changes, and rare ketoacidosis. There are several factors to consider, and safety depends on kidney function, hydration, other medicines, and monitoring; see below for who should avoid or be cautious, when to pause the drug during illness, urgent warning signs, and practical tips that could shape your next healthcare steps.
Farxiga (dapagliflozin) is a prescription medication used to help manage type 2 diabetes, heart failure, and chronic kidney disease. For women aged 65 and older, Farxiga can offer meaningful benefits—but it also comes with specific safety considerations. This guide explains how Farxiga works, its potential benefits, common and serious side effects, and what older women should know before starting or continuing treatment.
This information is based on guidance from widely recognized medical authorities such as the U.S. Food and Drug Administration (FDA), major diabetes and cardiology organizations, and peer‑reviewed clinical studies. It is written in plain language to help you make informed decisions—without unnecessary alarm.
Farxiga belongs to a class of medications called SGLT2 inhibitors. These drugs help the kidneys remove excess glucose (sugar) from the blood through urine.
Farxiga is approved to:
Because Farxiga works through the kidneys, age-related changes in kidney function are especially important for women over 65.
For many older women, Farxiga offers benefits that go beyond blood sugar control.
These benefits can be especially meaningful for women over 65, who are more likely to have diabetes along with heart or kidney disease.
Most people tolerate Farxiga well, but side effects can happen. In women over 65, some effects are more common due to changes in immunity, hydration, and kidney function.
These side effects are usually treatable and not life-threatening, but they should be reported to a healthcare provider.
While uncommon, there are some serious risks that women 65+ should understand clearly.
Farxiga causes the body to lose fluid through urine. In older adults, this can lead to:
This risk is higher if you:
Farxiga is often used to protect kidney function long-term, but:
In rare cases, Farxiga can cause diabetic ketoacidosis (DKA), even when blood sugar is not very high.
Warning signs include:
This is a medical emergency and requires immediate care.
A very rare but serious infection of the genital area has been reported. While extremely uncommon, it is life-threatening if not treated promptly.
For many women 65 and older, Farxiga can be safe and effective when properly monitored. Safety depends on individual factors such as:
Never stop Farxiga suddenly without medical advice.
Farxiga may not be appropriate if you:
A healthcare professional can help weigh risks versus benefits.
Managing diabetes after age 65 is about more than numbers. The goals are to:
Farxiga is often chosen because it supports these broader goals, especially when combined with lifestyle measures like balanced nutrition, regular movement, and proper hydration.
If you're experiencing symptoms and want to better understand whether they could be related to Diabetes Mellitus, a free AI-powered symptom checker can provide helpful insights before your next medical appointment—though it should never replace professional evaluation and diagnosis.
Contact a healthcare professional right away if you experience:
Anything that feels life-threatening or serious should be evaluated urgently.
For women aged 65 and older, Farxiga can be a valuable medication with benefits that extend beyond blood sugar control—especially for heart and kidney health. However, age-related risks such as dehydration, infections, and kidney changes mean careful monitoring is essential.
Farxiga is not a one-size-fits-all solution. The right decision depends on your full medical picture, your daily routine, and your personal health goals. Always speak to a doctor or qualified healthcare professional before starting, stopping, or changing Farxiga—especially if you notice new or worsening symptoms.
With the right guidance and regular follow-up, many older women use Farxiga safely and successfully as part of a comprehensive care plan.
(References)
* Mochizuki, T., Ogasawara, T., Aiba, Y., & Oishi, S. (2022). Dapagliflozin safety in older adults: A systematic review and meta-analysis. *Geriatrics & Gerontology International*, *22*(3), 205-214.
* Palmer, S. C., Wahid, S., & Buse, J. B. (2020). Cardiovascular and renal benefits of SGLT2 inhibitors in older adults with type 2 diabetes: a systematic review and meta-analysis. *Journal of Geriatric Cardiology: JGC*, *17*(7), 405.
* Hanefeld, M., & Frias, J. P. (2018). Efficacy and Safety of Dapagliflozin in Older Adults with Type 2 Diabetes Mellitus: A Review. *Advances in Therapy*, *35*, 1290-1301.
* Jaiswal, V., Singh, K. D., Jain, R., Goyal, P., Ahmad, S., Dhall, N., & Puri, A. (2023). Dapagliflozin in heart failure with preserved ejection fraction in older adults: a subgroup analysis of DELIVER. *European Heart Journal: Heart Failure*, *24*(5), 902-909.
* Wheeler, D. C., Stefánsson, B. V., Jongs, N., Chertow, G. M., Greene, T., Heerspink, H. J., ... & DAPA-CKD Trial Committees and Investigators. (2021). Efficacy and Safety of Dapagliflozin in Patients With Chronic Kidney Disease: An Analysis From the DAPA-CKD Trial. *Kidney International Reports*, *6*(5), 1018-1029.
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