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Published on: 2/2/2026

STI Screening Guidelines: When and How Often You Should Get Tested

Testing frequency for STIs depends on your risk: most adults should have at least one HIV test, get annual screening if under 25 or with new or multiple partners, and test every 3 to 6 months if higher risk, often for HIV, syphilis, chlamydia, and gonorrhea, including men who have sex with men, people with anonymous or multiple partners, sex workers, people who inject drugs, or those with a recent STI. Do not wait if you have symptoms or are pregnant, and ask a clinician which tests and sites you need, such as throat or rectal swabs when relevant. There are several factors to consider, and important details that could change your next steps are outlined below.

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Explanation

STI Screening Guidelines: When and How Often You Should Get Tested

Sexually transmitted infections (STIs) are common, and many people who have one do not notice symptoms right away—or at all. That is why regular screening is an important part of preventive healthcare. Understanding the frequency of STI testing that is right for you can help protect your health, your fertility, and your partners, without causing unnecessary worry.

This guide is based on widely accepted recommendations from credible medical authorities such as the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), and national sexual health guidelines used by physicians worldwide.


Why STI Screening Matters

STIs do not always cause pain or visible signs. In fact:

  • Many STIs can be present without symptoms for months or years
  • Untreated infections can lead to long-term health problems
  • Early detection makes treatment simpler and more effective
  • Knowing your status helps prevent unknowingly passing an infection to others

Screening is not about judgment—it is about information and prevention.


What Does "Frequency of STI Testing" Mean?

The frequency of STI testing refers to how often a person should be tested based on:

  • Sexual activity
  • Number of partners
  • Type of sexual contact (oral, vaginal, anal)
  • Use of protection (such as condoms)
  • Age and biological sex
  • Pregnancy status
  • Whether you or your partner have an STI

There is no single schedule that fits everyone. The goal is to test often enough to catch infections early, without unnecessary testing.


General STI Testing Guidelines

At Least Once in Your Lifetime

Most healthcare professionals recommend that all sexually active adults get tested for HIV at least once, regardless of perceived risk.


Annual Testing (Once a Year)

You should consider STI testing at least once a year if you:

  • Are sexually active and under age 25
  • Have more than one sexual partner
  • Have a new partner since your last test
  • Do not consistently use condoms
  • Are unsure of your partner's STI status

Annual screening commonly includes:

  • Chlamydia
  • Gonorrhea
  • Syphilis (in some cases)
  • HIV

More Frequent STI Testing (Every 3–6 Months)

More frequent testing may be recommended if you:

  • Have multiple or anonymous partners
  • Have sex with partners who have other partners
  • Are a man who has sex with men (MSM)
  • Engage in sex work
  • Use injectable drugs
  • Have had an STI in the past year

In these cases, healthcare providers often recommend testing every 3 to 6 months, especially for HIV, syphilis, gonorrhea, and chlamydia.

This higher frequency of STI testing helps catch infections early and reduce spread within sexual networks.


STI Screening by Specific Groups

Women and People with a Uterus

  • Chlamydia and gonorrhea:
    • Annually for sexually active people under 25
    • Annually for older individuals with risk factors
  • Pregnancy:
    • Early pregnancy screening for HIV, syphilis, hepatitis B
    • Repeat testing later in pregnancy if risk continues

Untreated STIs during pregnancy can affect both parent and baby, so testing is especially important.


Men and People with a Penis

  • No routine screening for all men, but testing is strongly recommended based on sexual behavior and risk
  • MSM are often advised to test more frequently, including throat and rectal testing when relevant

Teens and Young Adults

Young people have higher rates of certain STIs, largely due to biological factors and barriers to healthcare access. Regular testing is a responsible step, not a sign of risky behavior.


What Happens During an STI Test?

STI screening is usually quick and straightforward. Depending on what is being tested, it may include:

  • Urine sample
  • Blood test
  • Swab of the throat, genitals, or rectum
  • Physical exam (sometimes)

Many tests can be done during a single visit, and results are often available within days.


If You Have Symptoms—or Think Something Is Wrong

While routine screening is important, do not wait for your next scheduled test if you notice symptoms such as:

  • Unusual discharge
  • Burning during urination
  • Sores, blisters, or rashes
  • Pelvic or testicular pain
  • Bleeding between periods
  • Pain during sex

These symptoms do not always mean an STI, but they should be checked promptly.

If your concern is related to past or recent sexual harm, coercion, or distress and you're experiencing emotional or physical symptoms that may be connected, you can take a confidential first step by using a free Sexual Trauma symptom checker to better understand what you're going through and explore what kind of support might help.


What If Your Test Is Positive?

A positive STI test can feel overwhelming, but most STIs are:

  • Treatable
  • Curable (in the case of many bacterial infections)
  • Manageable with ongoing care (for viral infections)

Early treatment reduces complications and protects partners. Your healthcare provider can guide you on treatment, follow-up testing, and partner notification.


Talking to a Doctor Is Essential

Online information can be helpful, but it cannot replace personalized medical care. You should speak to a doctor or qualified healthcare provider if:

  • You have symptoms that could be serious or life-threatening
  • You test positive for an STI
  • You are pregnant or immunocompromised
  • You are unsure how often you should be tested
  • You feel anxious, confused, or overwhelmed

A doctor can help you decide the safest and most appropriate frequency of STI testing for your situation.


Key Takeaways on Frequency of STI Testing

  • Many STIs have no symptoms—testing is the only way to know
  • Testing frequency depends on sexual activity and risk, not personal worth
  • Annual testing is common; some people benefit from testing every 3–6 months
  • Prompt testing is important if symptoms appear
  • Medical guidance is essential for diagnosis, treatment, and prevention

STI screening is a normal part of caring for your health. Staying informed, getting tested at the right intervals, and seeking medical advice when needed are practical steps that support long-term well-being—for you and your partners.

(References)

  • * Grossman DC, Curry SJ, Barry MJ, Davidson KW, deGruy FV 3rd, Donahue C, et al. Screening for Chlamydia and Gonorrhea: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2021 Sep 14;326(10):956-973. doi: 10.1001/jama.2021.14695. PMID: 34515516.

  • * Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana MR, Caughey AB, et al. Screening for HIV Infection: US Preventive Services Task Force Recommendation Statement. JAMA. 2019 Jun 18;321(22):2204-2214. doi: 10.1001/jama.2019.6451. PMID: 31184841.

  • * Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Donahue KE, et al. Screening for Syphilis Infection in Nonpregnant Adults and Adolescents: US Preventive Services Task Force Recommendation Statement. JAMA. 2021 Sep 14;326(10):948-955. doi: 10.1001/jama.2021.14686. PMID: 34515514.

  • * Workowski KA, Bachmann LH, Chan PA, Johnston CM, Muzny PJ, Secor WE, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep. 2021 Jul 23;70(4):1-187. doi: 10.15585/mmwr.rr7004a1. PMID: 34293524.

  • * Grossman DC, Curry SJ, Barry MJ, Davidson KW, deGruy FV 3rd, Donahue C, et al. Screening for Hepatitis C Virus Infection in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement. JAMA. 2020 Mar 3;323(10):970-975. doi: 10.1001/jama.2020.1123. PMID: 32125501.

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