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Published on: 1/30/2026

Is gabapentin addictive?

Gabapentin is not addictive in the traditional sense and is not federally scheduled, but it can cause physical dependence and withdrawal if stopped abruptly, and misuse can occur at high doses or in people with substance use risk. There are several factors to consider, including added risks when combined with opioids, benzodiazepines, or alcohol and the importance of a gradual taper; see below for complete details and next steps to discuss with your clinician.

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Explanation

Is Gabapentin Addictive? A Clear, Evidence‑Based Answer

Gabapentin is a prescription medication that has been widely used for decades. It is commonly prescribed for nerve pain, seizures, and certain off‑label conditions such as restless legs syndrome and anxiety-related symptoms. Because gabapentin affects the nervous system, many people understandably ask: Is gabapentin addictive?

The short answer is gabapentin is not considered addictive in the same way as opioids, benzodiazepines, or stimulants, but it can be misused and can cause physical dependence in some people, particularly at higher doses or in specific risk groups.

Below is a balanced, medically accurate explanation based on credible clinical evidence and regulatory guidance.


What Is Gabapentin and How Does It Work?

Gabapentin is an anticonvulsant and nerve pain medication. It was originally developed to treat epilepsy and is now commonly prescribed for:

  • Neuropathic (nerve) pain
  • Partial seizures
  • Postherpetic neuralgia (pain after shingles)
  • Restless legs syndrome (off‑label)
  • Certain anxiety-related conditions (off‑label)

Gabapentin works by modulating calcium channels in the brain, which reduces excessive nerve signaling. Importantly, it does not directly activate dopamine reward pathways in the brain the way addictive drugs typically do.


Is Gabapentin Addictive?

Gabapentin is not classified as a controlled substance at the federal level in the United States. This reflects its low inherent addiction potential for most people when used as prescribed.

However, the full answer is more nuanced.

Gabapentin can cause:

  • Physical dependence in some individuals
  • Withdrawal symptoms if stopped abruptly
  • Misuse in certain high‑risk populations

Gabapentin does not typically cause:

  • Intense cravings
  • Compulsive drug-seeking behavior
  • Escalating use for euphoria in most patients

Addiction vs. Dependence: Why the Difference Matters

Understanding terminology helps reduce fear and confusion.

Addiction involves:

  • Loss of control over use
  • Cravings
  • Continued use despite harm

Physical dependence involves:

  • The body adapting to a medication
  • Withdrawal symptoms if the drug is stopped suddenly

Gabapentin can cause physical dependence without addiction, especially when used long term or at high doses.


Who Is at Higher Risk of Gabapentin Misuse?

Research shows that gabapentin misuse is uncommon in the general population, but risk increases in certain situations.

Higher‑risk groups include people who:

  • Have a history of substance use disorder
  • Are taking opioids or sedatives at the same time
  • Use higher-than-prescribed doses
  • Take gabapentin without medical supervision

Some U.S. states have classified gabapentin as a monitored medication due to increased misuse in combination with opioids. This does not mean gabapentin is unsafe—it means it requires appropriate oversight.


Can You Get “High” From Gabapentin?

At therapeutic doses, most people do not experience euphoria.

At very high doses, some individuals report:

  • Sedation
  • Dizziness
  • A sense of calm or dissociation

These effects are unpredictable and not reliable, which is why gabapentin is not commonly abused compared to other drugs.


Gabapentin Withdrawal: What to Know

Stopping gabapentin suddenly can lead to withdrawal symptoms, especially after long-term or high-dose use.

Possible withdrawal symptoms include:

  • Anxiety or agitation
  • Insomnia
  • Nausea
  • Sweating
  • Headache
  • Increased pain
  • Rarely, seizures

Withdrawal does not mean addiction—it means the nervous system needs time to adjust.

Safe stopping is key:

  • Doctors typically recommend gradual dose reduction (tapering)
  • Taper schedules are individualized

Never stop gabapentin abruptly without medical advice.


Is Gabapentin Safe When Used as Prescribed?

For most people, gabapentin is considered safe and effective when used under medical supervision.

Key safety points:

  • It does not damage organs when used correctly
  • It does not suppress breathing on its own
  • It has minimal drug interactions compared to many alternatives

However, combining gabapentin with opioids, alcohol, or benzodiazepines can increase the risk of sedation and breathing problems. This is why honest communication with your doctor matters.


Gabapentin and Seizures: An Important Note

Gabapentin is an anti‑seizure medication, and stopping it suddenly—especially in people with seizure disorders—can increase seizure risk.

If you or someone you care for has had seizures related to fever, illness, or medication changes, you may want to consider doing a free, online symptom check for Febrile Seizure to better understand warning signs and when to seek care.


Signs Gabapentin Use May Be a Problem

While uncommon, seek medical advice if you notice:

  • Taking more gabapentin than prescribed
  • Using it for reasons other than intended
  • Feeling unable to stop without discomfort
  • Mixing it with alcohol or other sedatives
  • Cognitive changes or excessive sleepiness

These do not automatically mean addiction, but they do mean a medication review is important.


What Do Medical Experts Agree On?

Based on guidance from neurologists, pain specialists, and public health agencies:

  • Gabapentin has a low addiction potential
  • Misuse is possible, particularly in high‑risk groups
  • Physical dependence can occur, especially with long‑term use
  • Gradual tapering prevents most withdrawal issues

The medical consensus supports continued use of gabapentin when it is clearly helping and properly monitored.


Practical Tips for Safe Gabapentin Use

  • Take gabapentin exactly as prescribed
  • Do not increase your dose on your own
  • Avoid mixing with alcohol unless your doctor approves
  • Report new side effects promptly
  • Never stop suddenly without guidance

The Bottom Line

Is gabapentin addictive?
For most people, no—gabapentin is not addictive in the traditional sense. However, it can cause physical dependence and withdrawal, and misuse is possible in certain situations.

When prescribed appropriately and monitored, gabapentin remains a valuable and often life‑improving medication.

If you have concerns about gabapentin, withdrawal symptoms, seizure risk, or any symptoms that could be serious or life‑threatening, speak to a doctor as soon as possible. Medical guidance is essential to ensure both safety and peace of mind.

(References)

  • * Evoy KE, Copeland PM, O'Connell JR, et al. Gabapentin and Pregabalin Misuse and Abuse: A Systematic Review. *Drugs*. 2017 Jul;77(10):1059-1094. doi:10.1007/s40265-017-0744-0. PMID: 28508933; PMCID: PMC5573891.

  • * Peckham AM, An SB, Evoy KE, et al. Gabapentin misuse and diversion: a systematic review and meta-analysis. *Drugs*. 2019 Oct;79(15):1615-1627. doi:10.1007/s40265-019-01186-0. PMID: 31440938.

  • * Smith BH, Nicholson KL, Webb LS, Jaffe JA. Gabapentin and pregabalin misuse and dependence: a systematic review. *Addiction*. 2016 Feb;111(2):227-39. doi:10.1111/add.12781. Epub 2015 Oct 13. PMID: 26344214.

  • * Manubay JM, Manubay AT, Wuest JR, et al. Prescription Opioid and Gabapentin Misuse among Patients with Chronic Pain: Prevalence and Characteristics. *Pain Pract*. 2017 Jul;17(6):750-761. doi:10.1111/papr.12563. Epub 2017 May 17. PMID: 28370908.

  • * Hellwig T, Hammer B, Inderwies R. Gabapentin abuse and withdrawal: a case series. *Am J Psychiatry*. 2014 Nov;171(11):1199-200. doi:10.1176/appi.ajp.2014.14060803. PMID: 25360667.

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