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Published on: 7/21/2026

Can hormonal changes or menstruation cause right upper abdominal pain in women?

Hormonal changes during menstruation can cause abdominal pain, but right upper abdominal pain specifically is uncommon. Menstrual cramps typically affect the lower abdomen and pelvis, not the upper right area where the liver and gallbladder are located. Right upper abdominal pain during your period may point to a separate underlying issue, such as gallbladder problems, liver conditions, or gastrointestinal concerns that happen to coincide with your cycle.

Because pinpointing the exact cause requires evaluating your full symptom picture, taking a free, instant, online symptom check is a smart next step. It can help you identify potential causes, understand urgency, and decide whether self-care, a doctor's visit, or urgent evaluation is right for you—all in just a few minutes.

Reviewed for medical accuracy: 07/20/2026

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Explanation

Hormonal changes during a woman's menstrual cycle can affect the body in various ways, including causing abdominal pain. While it is common to experience pain in the lower abdomen during menstruation, right upper abdominal pain is less typical. According to the medical literature provided, fluctuations in ovarian hormones can influence gastrointestinal symptoms, which might include abdominal discomfort.

  • Epigastric Pain and Menses: One reference suggests that epigastric pain, which is pain in the upper middle part of the abdomen, can be related to menstrual cycles. This indicates that while upper abdominal pain can occur, it is not necessarily specific to the right side.
  • Gastrointestinal Effects: Another study discusses how hormonal fluctuations can affect the gastrointestinal system. This means that hormonal changes might cause some abdominal discomfort, but again, right upper abdominal pain is not specifically highlighted.

In summary, while hormonal changes during menstruation can cause some abdominal pain, experiencing right upper abdominal pain is not commonly associated with menstruation based on the given references. If someone experiences unusual or severe pain, using a symptom checker can help identify possible causes before consulting a healthcare provider.

(References)

  • Podgaec S, Gonçalves MO, Klajner S, & Abrão MS. (2008). Epigastric pain relating to menses can be a symptom of .... Sao Paulo medical journal = Revista paulista de medicina, 18853038.

  • Pašalić E, Tambuwala MM, & Hromić-Jahjefendić A. (2023). Classification, pathophysiology, and treatment options. Pathology, research and practice, 37844487.

  • Heitkemper MM, & Chang L. (2009). Do fluctuations in ovarian hormones affect gastrointestinal .... Gender medicine, 19406367.

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