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Discomfort when my period comes
Headache
Breast pain
Tired all the time
Mood swings
Irritable
Stomach bloating
Low energy
Breast tenderness
Sore breasts
Menstrual pain
Not seeing your symptoms? No worries!
PMS refers to physical or mood changes that occur shortly before menstruation and typically resolve a few days after. PMS symptoms generally recur with each menstrual cycle and can negatively affect the women's normal life. PMS consists of both mental and physical symptoms, occurring 3-10 days before menstruation. Symptoms start to improve once menstruation begins. The cause of PMS is poorly understood, but is related to fluctuations in levels of female hormones. PMS can worsen underlying mood disorders such as anxiety and depression.
Your doctor may ask these questions to check for this disease:
Treatment of PMS mostly involves lifestyle changes like regular sleep cycles and a balanced diet. Medications can also help with muscle aches and stomach cramps. Counseling may be helpful in coping with the stress of this disorder. Hormonal birth control can be used to suppress the menstrual cycle or reduce it. For patients with severe symptoms that affect their work and personal life, medications such as antidepressants (SSRI's) can be used.
Reviewed By:
Ravi P. Chokshi, MD (Obstetrics and Gynecology (OBGYN), Critical Care)
Current Maternal Fetal Medicine Fellow with Dual board certification in Obstetrics & Gynecology and Critical Care Medicine. | 5+ years experience managing a general Ob/Gyn practice and working in the Intensive Care Unit. | Previously Physician Lead of a large single specialty practice with 8 Physicians and 10+ Advanced practitioners. | Member of the Society of Maternal Fetal Medicine Patient education committee. | Frequent Medscape Consult contributor.
Seiji Kanazawa, MD, PHD (Obstetrics and Gynecology (OBGYN))
Dr. Kanazawa graduated from the Niigata University Faculty of Medicine and received his Ph.D. from the Tohoku University Graduate School of Medicine. He is working on the front line of the General Perinatal Center, including the Tokyo Tama General Medical Center and the National Center for Research in Fertility Medicine, where he provides maternal and fetal care and undertakes clinical research. At Ubie, Dr. Kanazawa has been designing the Ubie AI Symptom Checker and has taken on the role of general obstetrics and gynecology consultation at FMC Tokyo Clinic by providing fetal ultrasound and prenatal consultation.
Content updated on Dec 6, 2024
Following the Medical Content Editorial Policy
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This questionnaire is customized to your situation and symptoms, including the following personal information:
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Q.
Is It Just PMS? Why Your Hormones Are Spiraling & Medically Approved Next Steps
A.
There are several factors to consider: what feels like PMS can range from normal premenstrual changes to PMDD or other conditions like thyroid disease, PCOS, perimenopause, or premenstrual worsening of depression or anxiety, especially if symptoms are severe, disruptive, cycles are irregular or heavy, or you have thoughts of self-harm that need urgent care. Medically approved next steps include tracking symptoms for 2 to 3 cycles, using proven lifestyle strategies, considering calcium, vitamin B6, or magnesium with clinician guidance, and discussing SSRIs, hormonal birth control, NSAIDs, and therapy; see below for the complete guidance and important nuances that could change the best next step for you.
References:
* Maršík, T., Vranovská, T., & Holubová, M. (2023). Premenstrual syndrome and premenstrual dysphoric disorder: current insights into etiology and treatment. *Journal of Biological Research-Thessaloniki*, *30*(1), 16.
* Back, S. N. (2022). Premenstrual Dysphoric Disorder: Neurobiology, Diagnosis and Treatment. *International Journal of Women's Health and Reproduction Sciences*, *10*(3), 118–123.
* Kresch, E., Lall, A., & Nierenberg, A. A. (2023). Treatment of Premenstrual Syndrome and Premenstrual Dysphoric Disorder: A Review. *Current Psychiatry Reports*, *25*(9), 481–488.
* Epperson, C. N., Steiner, M., & Hirschberg, L. M. (2021). Premenstrual Disorders: A Narrative Review of Diagnosis, Comorbidities, and Treatments. *The Primary Care Companion for CNS Disorders*, *23*(3), 20r02804.
* Nevatte, T., O'Brien, P. M., Bäckström, T., Endicott, J., Epperson, C. N., Eriksson, E., Gehlert, S., Halbreich, U., Ismail, K. M., Panay, N., Pearlstein, T., & Steiner, M. (2017). Premenstrual Syndrome and Premenstrual Dysphoric Disorder: Diagnosis and Treatment. *Current Problems in Obstetrics, Gynecology and Fertility*, *40*(3), 85–109.
Q.
Monthly Meltdown? Why Your Brain Hijacks Your Mood & Medical Next Steps
A.
Severe, cyclical mood swings before your period often signal PMDD, a brain-based sensitivity to normal hormonal shifts in the luteal phase where allopregnanolone acting on GABA receptors can trigger anxiety, depression, irritability, and physical symptoms that usually ease once bleeding starts. Proven next steps include SSRIs taken daily or only in the second half of the cycle, plus carefully chosen birth control since some types can worsen mood, along with lifestyle changes, CBT, and tracking symptoms for at least two cycles. If you have suicidal thoughts seek urgent care, and see the important details and caveats below to choose the best plan with your clinician.
References:
* Gyllenhammer, L., & Bäckström, T. (2020). The Neurobiology of Premenstrual Syndrome and Premenstrual Dysphoric Disorder. *Dialogues in Clinical Neuroscience*, *22*(4), 369–379. [PMID: 33437149]
* Rapkin, A. J., & Winer, S. A. (2020). Premenstrual Syndrome and Premenstrual Dysphoric Disorder: Diagnosis and Treatment. *Obstetrics and Gynecology Clinics of North America*, *47*(3), 395–408. [PMID: 32690342]
* Ma, H., & Ma, X. (2022). The Role of Ovarian Hormones in Premenstrual Syndrome and Premenstrual Dysphoric Disorder: A Narrative Review. *Neuropsychiatric Disease and Treatment*, *18*, 425–439. [PMID: 35273467]
* Schmidt, P. J., & Rubinow, D. R. (2018). The neurobiology of premenstrual dysphoric disorder. *Molecular Psychiatry*, *23*(5), 1083–1093. [PMID: 28243920]
* Backstrom, T., Gulin, L., & Wahlstrom, J. (2023). Update on the aetiology and management of premenstrual dysphoric disorder. *Current Opinion in Psychiatry*, *36*(3), 164–171. [PMID: 37042502]
Q.
Sudden Brain Fog? Why Your Luteal Phase Is a "Body Hijack" + Medically-Proven Next Steps
A.
Sudden brain fog in the luteal phase is often driven by normal hormone shifts, with progesterone’s calming effect slowing thinking, estrogen dips reducing memory and focus, and a heightened stress response that can make small problems feel bigger. Medically proven steps include stabilizing blood sugar, prioritizing sleep, adjusting workout intensity, considering evidence-backed supplements with clinician guidance, reducing cognitive load, and for severe PMS or PMDD, options like certain combined oral contraceptives or SSRIs. There are several factors to consider and important red flags to watch for, so see below for specifics and how to choose the right next steps for your situation.
References:
* Epperson, C. N., & Steiner, M. (2018). Cognition and the menstrual cycle. *Current Opinion in Psychiatry*, *31*(6), 460–465.
* Noll, S. K., Loehr, M. A., & Roesch, K. A. (2022). Cognitive performance across the menstrual cycle in women with and without premenstrual dysphoric disorder. *Archives of Clinical Neuropsychology*, *37*(2), 291–306.
* Reis, R. M., Faleiros, F. N., de Carvalho, S. R., & Resende-Rodrigues, A. P. (2022). The Effects of Progesterone on Cognitive Function in Women: A Systematic Review. *Current Women's Health Reviews*, *18*(2), 105–118.
* de Godoy, B. F., Rosa-Cunha, J. F., de Jesus, M. A., Lhullier, A. C. M., & de Mello, M. T. (2022). Impact of ovarian steroids on affective and cognitive domains during the menstrual cycle in women with and without premenstrual dysphoric disorder: a systematic review. *Archives of Women's Mental Health*, *25*(6), 1163–1182.
* Marjoribanks, J., Ayeleke, R. O., Lethaby, A., & Farquhar, C. (2017). Treatment options for premenstrual syndrome and premenstrual dysphoric disorder. *The Cochrane Database of Systematic Reviews*, *9*(9), CD006114.
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Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1ACOG Patient FAQ
https://www.acog.org/womens-health/faqs/premenstrual-syndromeACOG Painful periods
https://www.acog.org/womens-health/faqs/dysmenorrhea-painful-periodsACOG Practice Bulletin
https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2017/07/mental-health-disorders-in-adolescentsACOG Practice Bulletin Menstrual suppression
https://www.acog.org/clinical/clinical-guidance/clinical-consensus/articles/2022/09/general-approaches-to-medical-management-of-menstrual-suppression