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Published on: 1/28/2026

How does a person get inflammatory bowel disease?

Inflammatory bowel disease develops from a complex interaction of genetics, an overactive immune system, disrupted gut bacteria, and environmental triggers like smoking, certain infections, frequent antibiotic use, highly processed diets, and urban living. It is not caused by stress, poor hygiene, or “eating the wrong foods,” is not contagious, and is different from IBS; there are several factors to consider, and the complete details below can guide your risk awareness, when to seek care, and steps that may support gut health.

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Explanation

How Does a Person Get Inflammatory Bowel Disease (IBD)?

Inflammatory bowel disease (IBD) is a long-term condition that causes ongoing inflammation in the digestive tract. The two main types are Crohn's disease and ulcerative colitis. While the symptoms and affected areas of the gut differ between these conditions, the underlying question many people ask is the same: how does someone actually get IBD?

The short answer is that IBD does not have a single cause. Instead, it develops from a combination of genetic, immune, environmental, and gut-related factors. Understanding these can help reduce confusion, stigma, and unnecessary fear—while still respecting that IBD is a serious medical condition.


IBD Is Not Caused by Something You Did

One important point to clarify early is this: IBD is not caused by stress, personality, poor hygiene, or "eating the wrong foods." While stress and diet can affect symptoms, they do not cause the disease itself.

IBD is also:

  • Not contagious
  • Not a mental health disorder
  • Not the same as irritable bowel syndrome (IBS)

IBS and IBD can share symptoms, but IBD involves visible inflammation and tissue damage, while IBS does not.


The Core Factors Behind IBD

Medical research shows that IBD develops when several factors overlap. These include:

  • Genetics (family history)
  • An abnormal immune response
  • Changes in gut bacteria
  • Environmental triggers

Let's look at each of these in clear, practical terms.


1. Genetics: A Higher Risk, Not a Guarantee

Some people are born with genes that increase their risk of developing IBD.

Key points about genetics and IBD:

  • Having a parent or sibling with IBD raises your risk
  • Over 200 genes have been linked to IBD
  • Most people with these genes never develop IBD

This means genetics load the gun, but they do not pull the trigger on their own.


2. The Immune System: When Defense Goes Too Far

A central feature of IBD is an overactive immune response in the gut.

Normally, your immune system:

  • Protects you from harmful bacteria and viruses
  • Leaves harmless gut bacteria alone

In IBD, this balance breaks down. The immune system:

  • Mistakes normal gut bacteria for a threat
  • Launches ongoing inflammation
  • Damages the lining of the intestines over time

This inflammation does not turn off, which is why IBD is considered a chronic (long-lasting) autoimmune-related condition.


3. Gut Bacteria: A Disrupted Microbiome

Your digestive tract contains trillions of bacteria that help with:

  • Digestion
  • Vitamin production
  • Immune regulation

In people with IBD, studies show:

  • Less diversity in gut bacteria
  • Fewer beneficial bacteria
  • More bacteria linked to inflammation

This imbalance, often called dysbiosis, does not cause IBD on its own but plays a major role in triggering and maintaining inflammation.


4. Environmental Triggers: The Missing Piece

For many people, IBD symptoms begin after exposure to certain environmental factors.

These may include:

  • Smoking
    • Increases risk of Crohn's disease
    • Can worsen disease severity
  • Certain infections
    • Especially gastrointestinal infections earlier in life
  • Frequent antibiotic use
    • Particularly during childhood
  • Highly processed diets
    • May influence gut bacteria and immune responses
  • Urban living
    • Higher IBD rates compared to rural areas

These factors help explain why IBD is more common in industrialized countries and why rates are rising worldwide.


How Crohn's Disease and Ulcerative Colitis Differ

While they share causes, Crohn's disease and ulcerative colitis are not identical.

Crohn's Disease

  • Can affect any part of the digestive tract
  • Inflammation can go deep into the bowel wall
  • Often appears in patches

Ulcerative Colitis

  • Affects only the colon and rectum
  • Inflammation is limited to the inner lining
  • Usually spreads in a continuous pattern

Despite these differences, both are forms of IBD and arise from the same underlying mechanisms.


Is Stress a Cause of IBD?

Stress does not cause IBD. However:

  • Stress can worsen symptoms
  • Stress may trigger flare-ups in people already diagnosed
  • Chronic stress can affect immune function

Managing stress is an important part of living with IBD, but it is not a cure or root cause.


How IBD Is Different From IBS

Many people confuse IBD with IBS because symptoms can overlap.

IBD involves:

  • Ongoing inflammation
  • Tissue damage
  • Risk of complications
  • Abnormal blood tests and imaging

IBS involves:

  • Changes in bowel habits
  • Abdominal pain
  • No visible inflammation or damage

If you're experiencing digestive symptoms and want to better understand whether they align with Irritable Bowel Syndrome (IBS), a free AI-powered symptom checker can provide clarity and help you determine if you should seek further medical evaluation.


Who Is Most Likely to Develop IBD?

IBD can affect anyone, but it is more commonly diagnosed in:

  • Teenagers and young adults
  • People with a family history of IBD
  • Individuals living in industrialized countries
  • People who smoke (especially for Crohn's disease)

That said, many people diagnosed with IBD have no obvious risk factors.


Can IBD Be Prevented?

At this time, there is no proven way to prevent IBD. However, some steps may support overall gut health:

  • Avoid smoking
  • Use antibiotics only when necessary
  • Eat a balanced, fiber-rich diet when tolerated
  • Manage stress
  • Seek medical care early for ongoing digestive symptoms

These steps may not prevent IBD, but they can reduce complications and improve quality of life.


When to Speak to a Doctor

Digestive symptoms are common, but certain signs should not be ignored.

Speak to a doctor promptly if you experience:

  • Ongoing diarrhea lasting more than a few weeks
  • Blood in the stool
  • Unexplained weight loss
  • Persistent abdominal pain
  • Fever with digestive symptoms
  • Fatigue that does not improve

Some complications of IBD can be serious or life-threatening if untreated, so professional evaluation is essential.


The Bottom Line

A person gets inflammatory bowel disease (IBD) due to a complex interaction between genetics, immune system dysfunction, gut bacteria, and environmental triggers. It is not caused by stress, diet alone, or personal choices, and it is not something you can catch from someone else.

While IBD is a serious condition, effective treatments exist, and many people live full, active lives with proper care. If you have concerning symptoms or think you may be at risk, do not rely on guesswork—speak to a doctor for accurate diagnosis and appropriate treatment.

(References)

  • * Xia W, Su Q, Wang C, Lu Y, Yang J, Wu Y, Tang K, Li J. The pathogenesis of inflammatory bowel disease: A comprehensive review. Front Immunol. 2023 Aug 21;14:1229712. PMID: 37662990.

  • * Liu JZ, Anderson CA. The genetics of inflammatory bowel disease: from mechanisms to medicine. Nat Rev Gastroenterol Hepatol. 2023 May;20(5):308-323. PMID: 36976295.

  • * De Filippo S, Nuti F, Fiorino G. Environmental factors in inflammatory bowel disease: a narrative review. J Gastrointestin Liver Dis. 2023 Mar;32(1):5-14. PMID: 37012284.

  • * Franzosa EA, Sinha R, Khalili H, Vlamakis H, Xavier RJ. The gut microbiome and inflammatory bowel disease: from mechanisms to therapies. Nat Rev Gastroenterol Hepatol. 2023 May;20(5):324-340. PMID: 36976296.

  • * Nuti F, De Filippo S, Fiorino G. Immune system and inflammatory bowel disease: new insights into pathogenesis and therapies. Ther Adv Gastroenterol. 2022 Nov 28;15:17562848221142517. PMID: 36699268.

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