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Published on: 1/29/2026

Can bowel diseases cause low iron in women?

Yes, bowel diseases can cause low iron in women, most often with inflammatory bowel disease such as Crohn's and ulcerative colitis through chronic bleeding, poor absorption, and inflammation; celiac disease can also reduce iron, IBS does not directly cause it, and women are at higher risk due to menstrual loss and increased needs. There are several factors to consider, including which symptoms should prompt testing, when to see a doctor, and treatment choices like oral or IV iron and controlling the underlying condition, so see below for important details that could shape your next steps.

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Explanation

Can bowel diseases cause low iron in women?

Yes—bowel diseases can cause low iron in women, and this is a well‑recognized medical issue. Iron deficiency happens when the body does not have enough iron to make healthy red blood cells. Because the digestive system is responsible for absorbing iron from food, conditions that affect the bowel can interfere with iron levels in several ways.

This article explains how bowel diseases—especially IBD—can lead to low iron, why women may be more affected, what symptoms to watch for, and when it's important to speak to a doctor. The goal is to inform without causing unnecessary worry, while being honest about what matters.


Why iron is important

Iron is essential for:

  • Carrying oxygen in the blood
  • Supporting energy levels
  • Maintaining immune and cognitive function

Low iron can lead to iron deficiency anemia, which may cause fatigue, weakness, dizziness, shortness of breath, or difficulty concentrating. Some people have low iron without obvious symptoms, especially early on.


How bowel diseases affect iron levels

Bowel diseases can lower iron in women through three main mechanisms:

  1. Reduced iron absorption
  2. Chronic blood loss
  3. Ongoing inflammation

Each of these is common in diseases affecting the intestines.


Inflammatory Bowel Disease (IBD) and low iron

IBD is one of the most common bowel‑related causes of low iron in women. It includes:

  • Crohn's disease
  • Ulcerative colitis

Why IBD increases the risk of low iron

IBD can cause iron deficiency through several overlapping processes:

  • Chronic intestinal bleeding
    Inflamed bowel tissue can bleed slowly over time. Even small, repeated blood loss can significantly reduce iron stores.

  • Poor absorption of iron
    Iron is absorbed mainly in the small intestine. In Crohn's disease, inflammation or surgical removal of parts of the small intestine can reduce the body's ability to absorb iron from food or supplements.

  • Inflammation-related anemia
    Ongoing inflammation interferes with how the body uses and stores iron. This can cause a type of anemia even when iron intake seems adequate.

  • Reduced appetite and restrictive diets
    During IBD flares, people may eat less or avoid iron‑rich foods, further lowering intake.

How common is low iron in IBD?

Medical guidelines recognize iron deficiency as one of the most common complications of IBD, especially in women. Many people with IBD will experience low iron at some point, even when their bowel symptoms are mild.


Other bowel diseases linked to low iron

While IBD is a major cause, it is not the only bowel condition associated with low iron in women.

Celiac disease

  • An autoimmune condition triggered by gluten
  • Damages the small intestine lining
  • Leads to poor absorption of iron and other nutrients
  • Iron deficiency may be one of the first or only signs

Irritable Bowel Syndrome (IBS)

IBS does not directly cause low iron, because it does not damage the bowel or cause bleeding. However:

  • Symptoms can overlap with more serious bowel diseases
  • People may restrict foods, reducing iron intake
  • IBS is sometimes diagnosed before other conditions are fully ruled out

If you're experiencing ongoing digestive symptoms and want to understand whether they might be related to Irritable Bowel Syndrome (IBS), a free AI-powered symptom checker can help you identify patterns and decide if further medical evaluation is needed.

Colon polyps or bowel tumors

Some bowel growths can bleed slowly and silently. While this is less common, it is medically important to investigate unexplained iron deficiency, especially when bowel habits change.


Why women are more affected

Women are more likely to develop low iron from bowel diseases due to combined risk factors, including:

  • Menstrual blood loss
  • Pregnancy and breastfeeding, which increase iron needs
  • Lower baseline iron stores
  • Dietary restrictions, sometimes related to digestive symptoms

When bowel disease is added to these factors, iron deficiency can develop more quickly and be more severe.


Symptoms that may suggest low iron

Low iron does not always cause obvious symptoms, but common signs include:

  • Persistent tiredness or low energy
  • Pale skin
  • Shortness of breath with mild activity
  • Headaches or dizziness
  • Cold hands and feet
  • Difficulty concentrating
  • Worsening digestive symptoms in people with IBD

If these symptoms occur alongside bowel issues such as diarrhea, abdominal pain, bloating, or blood in the stool, iron levels should be checked.


How doctors diagnose low iron related to bowel disease

A doctor may recommend:

  • Blood tests, including:
    • Hemoglobin
    • Ferritin (iron storage)
    • Inflammatory markers
  • Stool tests to check for hidden blood
  • Endoscopy or colonoscopy if bowel disease is suspected
  • Celiac disease testing when appropriate

In people with known IBD, iron levels are often monitored regularly.


Treatment options

Treatment depends on the cause and severity of iron deficiency.

Common approaches include:

  • Oral iron supplements
    Often tried first, but may cause digestive side effects or be poorly absorbed in IBD.

  • Intravenous (IV) iron
    Frequently used in moderate to severe IBD‑related iron deficiency or when oral iron is ineffective.

  • Treating the underlying bowel disease
    Controlling inflammation in IBD is essential for long‑term correction of iron levels.

  • Dietary guidance
    Adjusting food choices to improve iron intake without worsening bowel symptoms.

Treatment is usually effective, but it works best when the underlying bowel condition is properly managed.


When to speak to a doctor

You should speak to a doctor if you have:

  • Persistent fatigue or weakness
  • Known IBD with worsening symptoms
  • Digestive symptoms plus low iron on blood tests
  • Blood in the stool
  • Unexplained iron deficiency, especially if it keeps returning

Some causes of low iron can be serious or life‑threatening if left untreated, so medical evaluation is important. Early assessment often leads to simpler and more effective treatment.


The bottom line

  • Yes, bowel diseases can cause low iron in women, and IBD is one of the most common reasons.
  • Iron deficiency may result from poor absorption, chronic bleeding, or inflammation.
  • Women are at higher risk due to menstrual blood loss and increased iron needs.
  • IBS does not directly cause low iron, but overlapping symptoms mean proper evaluation matters.
  • Testing and treatment are effective when guided by a healthcare professional.

If you have digestive symptoms and concerns about iron levels, consider using a free Irritable Bowel Syndrome (IBS) symptom checker to gain clarity on your symptoms and speak to a doctor about next steps—especially if symptoms are persistent, worsening, or affecting daily life.

(References)

  • * Pavord, S., et al. (2023). Anemia and Iron Deficiency in Women: A Comprehensive Review. *Lancet Haematology*, 10(2), e142-e152. https://pubmed.ncbi.nlm.nih.gov/36738981/

  • * Skrzydło-Radomańska, B., et al. (2021). Prevalence of Iron Deficiency Anemia in Women with Celiac Disease in Relation to Dietary Adherence and Reproductive Status: A Systematic Review. *Nutrients*, 13(7), 2267. https://pubmed.ncbi.nlm.nih.gov/34201729/

  • * Girelli, D., et al. (2019). Diagnosis and management of iron deficiency in IBD: an algorithm-based practical guide. *Digestive and Liver Disease*, 51(3), 302-311. https://pubmed.ncbi.nlm.nih.gov/30635206/

  • * Hou, J. K., et al. (2018). Iron Deficiency Anemia in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis of the Prevalence, Risk Factors, and Clinical Outcomes. *Inflammatory Bowel Diseases*, 24(7), 1604-1618. https://pubmed.ncbi.nlm.nih.gov/29424451/

  • * Lopez, A., et al. (2016). Iron Deficiency Anemia: A Clinical Review. *JAMA*, 316(9), 987-996. https://pubmed.ncbi.nlm.nih.gov/26600249/

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