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Published on: 1/29/2026

Why does inflammation affect bowel movements?

Inflammation changes bowel movements through several mechanisms: it can speed up or slow gut motility, damage the intestinal lining that absorbs water, trigger extra fluid and electrolyte secretion, irritate gut nerves, and disrupt gut bacteria, which can cause diarrhea or constipation, urgency, cramping, mucus or blood, and dehydration. There are several factors to consider; see below to understand more. In conditions like IBD these changes are visible and can flare and remit, while IBS does not show tissue damage, and the differences, red flags, and when to seek care are explained below to help guide your next steps.

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Explanation

Why Does Inflammation Affect Bowel Movements?

Inflammation in the digestive tract has a direct and meaningful impact on how your bowels work. Whether inflammation is mild and temporary or part of a long-term condition like IBD (Inflammatory Bowel Disease), it can change how often you go to the bathroom, what your stool looks like, and how comfortable bowel movements feel. Understanding why this happens can help you recognize when symptoms are manageable—and when it's important to speak to a doctor.


What Is Inflammation in the Gut?

Inflammation is the body's natural response to injury, infection, or irritation. In the gut, it involves the immune system becoming active in the lining of the intestines.

When inflammation is present:

  • Blood flow to the gut increases
  • Immune cells release chemicals to fight perceived threats
  • The intestinal lining may swell, weaken, or become damaged

In short bursts, inflammation can be helpful. But ongoing inflammation—such as in IBD, which includes Crohn's disease and ulcerative colitis—can disrupt normal digestion and bowel control.


How Normal Bowel Movements Work

To understand how inflammation interferes, it helps to know what normally happens:

  • Food is broken down in the stomach and small intestine
  • Nutrients are absorbed through the intestinal lining
  • The large intestine absorbs water and forms stool
  • Muscles in the colon move stool forward in a controlled way

This process relies on healthy nerves, muscles, and a strong intestinal lining. Inflammation can interfere with all three.


Key Ways Inflammation Affects Bowel Movements

1. Faster or Slower Gut Movement

Inflammation can change how quickly stool moves through the intestines.

  • Faster movement means less water is absorbed → loose stools or diarrhea
  • Slower movement can lead to constipation and bloating

In IBD, inflammation often speeds things up, which is why diarrhea is a common symptom.


2. Damage to the Intestinal Lining

The intestinal lining acts as a barrier and an absorption surface. Inflammation can:

  • Reduce the ability to absorb water and nutrients
  • Cause small breaks or ulcers in the lining
  • Allow fluid and mucus to leak into the stool

This can result in:

  • Watery stools
  • Mucus in stool
  • Blood in stool (more common in IBD than in functional conditions)

3. Increased Sensitivity and Urgency

Inflammation irritates the nerves in the gut, making them more sensitive.

This can cause:

  • A sudden, strong urge to have a bowel movement
  • Cramping or pain before or during bowel movements
  • A feeling of incomplete emptying

Even small amounts of stool can trigger urgency when inflammation is present.


4. Changes in Gut Bacteria

A healthy gut depends on a balanced community of bacteria. Inflammation can disrupt this balance.

When gut bacteria are altered:

  • Gas production may increase
  • Stool consistency can change
  • The immune system may stay activated longer

This cycle is especially relevant in IBD, where inflammation and bacterial imbalance can reinforce each other.


5. Excess Fluid and Electrolyte Secretion

Inflammation triggers the intestines to release fluid and salts.

This leads to:

  • Frequent, loose bowel movements
  • Dehydration if fluid loss is significant
  • Fatigue related to electrolyte imbalance

This mechanism explains why inflammatory diarrhea is often harder to control than diet-related diarrhea.


Inflammation in IBD vs. IBS: An Important Distinction

People often confuse IBD with IBS (Irritable Bowel Syndrome), but they are not the same.

IBD (Inflammatory Bowel Disease)

  • Includes Crohn's disease and ulcerative colitis
  • Involves visible inflammation and tissue damage
  • Can cause bleeding, anemia, weight loss, and nutrient deficiencies
  • Requires medical monitoring and treatment

IBS (Irritable Bowel Syndrome)

  • A functional gut disorder
  • No visible inflammation or tissue damage
  • Symptoms are related to gut sensitivity and motility
  • Not life-threatening, but can affect quality of life

If you're experiencing digestive symptoms and aren't sure what's causing them, a free assessment tool like Ubie's Irritable Bowel Syndrome (IBS) symptom checker can help you understand your symptoms and decide whether to seek medical care.


Why Inflammation Can Make Symptoms Come and Go

Inflammation isn't always constant. In IBD, many people experience:

  • Flare-ups, when inflammation is active and symptoms worsen
  • Remission, when inflammation is controlled and bowel movements improve

Triggers for inflammation may include:

  • Infections
  • Certain medications (like NSAIDs)
  • Ongoing stress
  • Dietary factors (varies by individual)

This explains why bowel habits may seem unpredictable over time.


Common Bowel Symptoms Linked to Inflammation

Inflammation can cause a wide range of bowel changes, including:

  • Diarrhea that lasts more than a few days
  • Urgent need to use the bathroom
  • Blood or mucus in stool
  • Abdominal cramping
  • Nighttime bowel movements
  • Fatigue related to frequent stooling

Not everyone will have all of these, and having one symptom does not automatically mean you have IBD. Still, persistent symptoms deserve attention.


When Inflammation Becomes Serious

While this topic doesn't need to be alarming, it's important to be honest: chronic inflammation in the gut can lead to complications if left untreated.

These may include:

  • Dehydration and electrolyte problems
  • Anemia from blood loss
  • Narrowing of the intestines (more common in Crohn's disease)
  • Reduced quality of life

This is why ongoing bowel changes should not be ignored, especially if they are worsening or interfering with daily activities.


What You Can Do Next

If inflammation may be affecting your bowel movements:

  • Track your symptoms (frequency, pain, blood, triggers)
  • Notice patterns, not just isolated bad days
  • Avoid self-diagnosing, especially when symptoms persist

Most importantly, speak to a doctor if you experience:

  • Blood in your stool
  • Unintentional weight loss
  • Ongoing diarrhea or constipation
  • Severe abdominal pain
  • Symptoms that wake you at night

These can sometimes point to conditions like IBD or other serious digestive diseases that require medical care.


The Bottom Line

Inflammation affects bowel movements because it disrupts how the intestines move, absorb fluid, sense stool, and protect themselves. In conditions like IBD, this inflammation is real, measurable, and potentially damaging if untreated. While not every bowel change is dangerous, persistent or severe symptoms should always be discussed with a healthcare professional.

Listening to your body, learning the difference between inflammatory and functional conditions, and seeking proper evaluation can help protect both your digestive health and your peace of mind.

(References)

  • * Stengel, A., & Tache, Y. (2020). Altered Intestinal Motility and Function in Inflammatory Bowel Disease. *Frontiers in Physiology*, *11*, 767.

  • * Morando, F., Pastore, A., & Varese, M. (2022). Immune Cells and the Enteric Nervous System: A Cross-Talk Modulating Gut Motility in Health and Disease. *Cells*, *11*(16), 2506.

  • * Stasi, K., & Tache, Y. (2018). Mechanisms of altered gut motility in inflammatory bowel disease. *Alimentary Pharmacology & Therapeutics*, *48*(2), 160-175.

  • * Hughes, P. A., & Spiller, R. C. (2017). The impact of inflammation on gut motility and functional gastrointestinal disorders. *Journal of Gastroenterology*, *52*(10), 1047-1057.

  • * Wouters, M. M., Vicario, M., & Santos, J. (2013). Role of mast cells in gut motility and functional gastrointestinal disorders. *Alimentary Pharmacology & Therapeutics*, *37*(11), 1011-1025.

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