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Published on: 1/29/2026
The biggest trigger for IBS is stress acting through the brain gut connection, which heightens gut sensitivity and can speed up or slow down bowel movements. There are several factors to consider. See below to understand how foods, hormones, and past infections can amplify flares, plus practical ways to manage symptoms and the red flags that mean you should see a doctor.
Irritable Bowel Syndrome (IBS) is a common digestive condition that affects how the gut functions rather than causing visible damage. People with IBS often experience abdominal pain, bloating, gas, diarrhea, constipation, or a mix of both. One of the most common questions patients ask is: What actually triggers IBS symptoms?
For most people, stress and the way the brain communicates with the gut are the single biggest triggers for IBS. However, IBS is not caused by just one thing. Symptoms usually flare when stress interacts with sensitive digestion, certain foods, hormones, or past gut infections.
Below is a clear, evidence-based breakdown of the main trigger of IBS, along with other important contributors, explained in simple terms.
The digestive system has its own nervous system, often called the "second brain." This gut nervous system is directly connected to the brain through nerves and chemical messengers. This relationship is known as the brain–gut axis.
In people with IBS:
This is why stress is widely considered the most powerful and consistent trigger for IBS symptoms, supported by research from gastroenterology and mental health fields.
Stress does not cause IBS on its own, but it can strongly trigger symptoms by:
Importantly, this is not "all in your head." The symptoms are real, physical, and measurable.
Many people notice that IBS symptoms flare before stressful events, such as travel, exams, deadlines, or social situations.
Food is often blamed first, and while diet matters, it is usually not the root cause of IBS. Instead, food triggers tend to worsen symptoms in an already sensitive gut.
Some foods are harder to digest and can ferment in the gut, causing gas and discomfort. These include foods high in FODMAPs (a group of fermentable carbohydrates).
Common examples include:
For many people with IBS, symptoms improve when trigger foods are reduced during flares, not necessarily eliminated forever.
This is why food triggers are considered contributors, not the primary trigger.
People with IBS often have visceral hypersensitivity, meaning the gut nerves overreact to normal sensations.
This can cause:
Stress amplifies this sensitivity, which explains why emotional triggers and physical symptoms are so closely linked in IBS.
Some people develop IBS after a stomach infection, known as post-infectious IBS.
This can happen after:
In these cases:
While infections can trigger the start of IBS, stress remains the most common trigger for ongoing symptoms.
Hormonal changes can influence IBS, particularly in women.
Some people notice worse symptoms:
Hormones can affect gut movement and pain perception, but again, they tend to modify symptoms rather than act as the main trigger.
IBS is best understood as a pattern, not a single disease with one cause.
Most people have a combination of:
However, across large studies and clinical practice, stress consistently stands out as the strongest and most reliable trigger for symptom flares.
Understanding the biggest trigger helps guide effective management.
Most people benefit from addressing IBS on multiple levels:
IBS management works best when it focuses on calming the gut–brain connection, not just avoiding foods.
If you're experiencing digestive symptoms and want to understand whether they align with IBS, Ubie's free AI-powered Irritable Bowel Syndrome (IBS) symptom checker can help you identify patterns and provide guidance on what to discuss with your healthcare provider.
While IBS itself is not life-threatening, some symptoms are not typical of IBS and need medical attention.
Speak to a doctor promptly if you experience:
These symptoms may indicate a condition more serious than IBS and should not be ignored.
If IBS symptoms are affecting your daily life, don't try to manage them alone. Speak to a doctor to rule out serious conditions and to build a plan that fits your body and your life.
(References)
* Lacy BE, Mearin F, Ford AC. Irritable Bowel Syndrome: A Clinical Update. Gastroenterology. 2023 Nov;165(5):1116-1132. doi: 10.1053/j.gastro.2023.08.031. Epub 2023 Aug 29. PMID: 37648356.
* Ohman L, Simrén M. Irritable bowel syndrome: novel insights on mechanisms and future therapies. Nat Rev Gastroenterol Hepatol. 2023 Oct;20(10):631-649. doi: 10.1038/s41575-023-00799-w. Epub 2023 Jul 3. PMID: 37391503.
* Drossman DA, Tack J. Update on the Etiopathogenesis and Management of Irritable Bowel Syndrome. Gastroenterol Hepatol (N Y). 2023 May;19(5):269-276. PMID: 37275815; PMCID: PMC10231940.
* Altomare A, Di Stefano M, Di Sabatino A, Pallotta N, Stasi E, Pizzoferrato M, De Luca A, Gasbarrini A, Barbara G. Dietary Triggers in Irritable Bowel Syndrome: A Review of the Current Literature. Dig Dis Sci. 2022 Aug;67(8):3639-3657. doi: 10.1007/s10620-021-07347-1. Epub 2022 Jan 7. PMID: 34999718; PMCID: PMC9339243.
* Koloski NA, Jones M, Koloski E, Quigley EMM, Talley NJ. Stress and Irritable Bowel Syndrome: A Bidirectional Relationship. Front Psychiatry. 2022 Jun 3;13:883838. doi: 10.3389/fpsyt.2022.883838. PMID: 35721867; PMCID: PMC9204060.
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