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Published on: 1/29/2026

Why is IBS more common in women?

Women are diagnosed about 1.5 to 2 times more often, likely due to hormone effects on the gut, sex differences in gut brain communication and pain processing, slower colon motility, immune differences, more common overlapping conditions like pelvic floor dysfunction and endometriosis, and greater stress exposure and health seeking that increase detection. There are several factors to consider; see below for how symptoms vary with the menstrual cycle, pregnancy, and menopause, which red flags mean you should see a doctor, and the full set of treatment options you can discuss next.

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Explanation

Why Is IBS More Common in Women?

Irritable Bowel Syndrome (IBS) is a long-term digestive condition that affects how the gut works. It commonly causes symptoms like abdominal pain, bloating, gas, constipation, diarrhea, or a mix of both. IBS is not life-threatening, but it can significantly affect daily life.

Across many countries and cultures, women are diagnosed with IBS more often than men. Most large population studies suggest that women are about 1.5 to 2 times more likely to have IBS. This difference is well documented in research from gastroenterology, endocrinology, and neuroscience. There is no single cause, but rather a combination of biological, hormonal, neurological, psychological, and social factors.

Below is a clear, evidence-based explanation of why IBS is more common in women, using plain language and credible medical understanding.


1. Hormones Play a Major Role

One of the strongest explanations for why IBS is more common in women involves female sex hormones, particularly estrogen and progesterone.

These hormones influence how the digestive system works in several ways:

  • They affect gut muscle movement, which controls how quickly food moves through the intestines
  • They influence pain sensitivity in the gut
  • They interact with gut-brain signaling, which is central to IBS

Menstrual Cycle Effects

Many women with IBS notice that symptoms change during their menstrual cycle:

  • Symptoms often worsen just before or during menstruation
  • Abdominal pain and bloating may increase
  • Bowel habits may shift toward diarrhea or constipation

This pattern suggests that hormonal fluctuations, not just stress or diet, can trigger IBS symptoms.

Pregnancy and Menopause

  • During pregnancy, changes in hormone levels and gut movement may worsen or sometimes improve IBS
  • After menopause, some women report symptom improvement, supporting the idea that estrogen influences IBS

2. Differences in Gut-Brain Communication

IBS is considered a disorder of gut-brain interaction, meaning the digestive system and the nervous system do not communicate smoothly.

Research shows that:

  • Women tend to have greater sensitivity to gut pain
  • The brain may process digestive signals differently in women than in men
  • Signals from the gut may feel more intense, even when there is no visible damage

This does not mean symptoms are "in the head." The pain is real. The difference lies in how signals are processed and perceived.


3. Slower Gut Motility in Women

On average, women tend to have slower movement of food through the intestines, especially in the colon.

This can lead to:

  • Constipation-predominant IBS (IBS-C)
  • Increased bloating and gas
  • More abdominal discomfort

Men are more likely to have diarrhea-predominant IBS, while women more often experience constipation or mixed symptoms.

Hormones, muscle function, and nervous system signaling all contribute to these differences.


4. Higher Rates of Certain Triggers in Women

Some known IBS triggers are more common in women, which may increase diagnosis rates.

These include:

  • Pelvic floor dysfunction, which can affect bowel movements
  • Endometriosis, which can worsen IBS symptoms or be mistaken for IBS
  • History of gastrointestinal infections, which can lead to post-infectious IBS
  • Use of certain medications, including some pain relievers and hormonal treatments

IBS often overlaps with other conditions that are also more common in women, making symptoms more noticeable and more likely to be evaluated.


5. Stress, Trauma, and the Nervous System

Stress does not cause IBS, but it can strongly influence symptoms.

Women, on average, have higher reported rates of:

  • Chronic stress
  • Anxiety and depression
  • Past trauma, including early-life stress

These factors affect the autonomic nervous system, which controls digestion.

Important points to understand:

  • IBS is not a mental illness
  • Stress can change how the gut functions and how pain is felt
  • The gut and brain are closely connected through nerves and hormones

Addressing stress can improve symptoms, but it is not a cure on its own.


6. Differences in Health-Seeking Behavior and Diagnosis

Another reason IBS appears more common in women is diagnostic patterns.

Women are:

  • More likely to seek medical care for digestive symptoms
  • More likely to discuss pain, bloating, and bowel changes
  • More likely to receive an IBS diagnosis once serious conditions are ruled out

Men may experience IBS but are less likely to report symptoms or seek care, which may lead to underdiagnosis.


7. Immune System Differences

Emerging research suggests that low-grade immune activation may play a role in IBS for some people.

Women generally have:

  • Stronger immune responses
  • Higher risk of autoimmune and inflammatory conditions

This may contribute to increased gut sensitivity and inflammation at levels too low to show up on standard tests but still capable of causing symptoms.


8. IBS Is Real, Manageable, and Not Dangerous

It is important to be clear:

  • IBS does not cause cancer
  • IBS does not damage the intestines
  • IBS does not shorten life expectancy

However, symptoms can be disruptive and deserve attention. Many women manage IBS successfully with:

  • Diet adjustments
  • Stress management
  • Targeted medications
  • Pelvic floor therapy
  • Gut-directed psychological therapies

Understanding why IBS is more common in women helps remove blame and stigma and supports better care.


When to Check Your Symptoms

If you're experiencing ongoing digestive symptoms like abdominal pain, bloating, constipation, diarrhea, or changes in bowel habits, Ubie's free AI-powered symptom checker can help you evaluate whether your symptoms match Irritable Bowel Syndrome (IBS) and guide your next steps with personalized insights.


When to Speak to a Doctor

While IBS itself is not life-threatening, some symptoms should never be ignored. You should speak to a doctor promptly if you experience:

  • Unexplained weight loss
  • Blood in the stool
  • Persistent vomiting
  • Severe or worsening pain
  • Symptoms that wake you from sleep
  • New symptoms after age 50
  • A family history of colon cancer, inflammatory bowel disease, or celiac disease

A doctor can rule out serious conditions and help confirm whether IBS is the most likely explanation.


Key Takeaways

  • IBS is more common in women due to hormones, gut-brain differences, immune responses, and social factors
  • Symptoms are real, physical, and influenced by biology
  • IBS is manageable, even if it is long-term
  • Understanding your body is the first step toward better control

If IBS symptoms are affecting your quality of life, do not dismiss them—and do not face them alone. A healthcare professional can help guide safe, effective treatment tailored to your needs.

(References)

  • * Ohlsson B. Sex and Gender Differences in Irritable Bowel Syndrome. J Clin Med. 2023 Aug 24;12(17):5524. doi: 10.3390/jcm12175524. PMID: 37637497; PMCID: PMC10488057.

  • * Bajaj N, Tarbell S, Madan A, Sharma D, Chey WD, Eswaran S. Sex Differences in Irritable Bowel Syndrome: A Review of Biological and Psychological Factors. J Neurogastroenterol Motil. 2020 Jul 30;26(3):285-299. doi: 10.5056/jnm20021. PMID: 32338600; PMCID: PMC7378771.

  • * Khan N, Gupta S, Kichloo A, Al-Otaibi F, Khan N, Singh A, Darr U. Sex Differences in Irritable Bowel Syndrome: A Role for Visceral Pain and the Gut Microbiome. Cureus. 2023 Jun 16;15(6):e40502. doi: 10.7759/cureus.40502. PMID: 37454848; PMCID: PMC10352128.

  • * Mulak A, Tache Y, Million M. Sex and Gender in Irritable Bowel Syndrome: A Narrative Review of Pathophysiology and Clinical Impact. Gastroenterol Clin North Am. 2019 Mar;48(1):141-163. doi: 10.1016/j.gtc.2018.09.006. PMID: 30678850; PMCID: PMC6698628.

  • * Kim S, Kim K, Kim TW, Jung ES, Choi B, Jo HJ, Lee JE. Sex hormones in irritable bowel syndrome: a review of current knowledge. J Gastroenterol Hepatol. 2022 Feb;37(2):299-307. doi: 10.1111/jgh.15570. Epub 2021 Jul 22. PMID: 34293976.

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