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Published on: 1/29/2026
Women are diagnosed about 1.5 to 2 times more often, likely due to hormone effects on the gut, sex differences in gut brain communication and pain processing, slower colon motility, immune differences, more common overlapping conditions like pelvic floor dysfunction and endometriosis, and greater stress exposure and health seeking that increase detection. There are several factors to consider; see below for how symptoms vary with the menstrual cycle, pregnancy, and menopause, which red flags mean you should see a doctor, and the full set of treatment options you can discuss next.
Irritable Bowel Syndrome (IBS) is a long-term digestive condition that affects how the gut works. It commonly causes symptoms like abdominal pain, bloating, gas, constipation, diarrhea, or a mix of both. IBS is not life-threatening, but it can significantly affect daily life.
Across many countries and cultures, women are diagnosed with IBS more often than men. Most large population studies suggest that women are about 1.5 to 2 times more likely to have IBS. This difference is well documented in research from gastroenterology, endocrinology, and neuroscience. There is no single cause, but rather a combination of biological, hormonal, neurological, psychological, and social factors.
Below is a clear, evidence-based explanation of why IBS is more common in women, using plain language and credible medical understanding.
One of the strongest explanations for why IBS is more common in women involves female sex hormones, particularly estrogen and progesterone.
These hormones influence how the digestive system works in several ways:
Many women with IBS notice that symptoms change during their menstrual cycle:
This pattern suggests that hormonal fluctuations, not just stress or diet, can trigger IBS symptoms.
IBS is considered a disorder of gut-brain interaction, meaning the digestive system and the nervous system do not communicate smoothly.
Research shows that:
This does not mean symptoms are "in the head." The pain is real. The difference lies in how signals are processed and perceived.
On average, women tend to have slower movement of food through the intestines, especially in the colon.
This can lead to:
Men are more likely to have diarrhea-predominant IBS, while women more often experience constipation or mixed symptoms.
Hormones, muscle function, and nervous system signaling all contribute to these differences.
Some known IBS triggers are more common in women, which may increase diagnosis rates.
These include:
IBS often overlaps with other conditions that are also more common in women, making symptoms more noticeable and more likely to be evaluated.
Stress does not cause IBS, but it can strongly influence symptoms.
Women, on average, have higher reported rates of:
These factors affect the autonomic nervous system, which controls digestion.
Important points to understand:
Addressing stress can improve symptoms, but it is not a cure on its own.
Another reason IBS appears more common in women is diagnostic patterns.
Women are:
Men may experience IBS but are less likely to report symptoms or seek care, which may lead to underdiagnosis.
Emerging research suggests that low-grade immune activation may play a role in IBS for some people.
Women generally have:
This may contribute to increased gut sensitivity and inflammation at levels too low to show up on standard tests but still capable of causing symptoms.
It is important to be clear:
However, symptoms can be disruptive and deserve attention. Many women manage IBS successfully with:
Understanding why IBS is more common in women helps remove blame and stigma and supports better care.
If you're experiencing ongoing digestive symptoms like abdominal pain, bloating, constipation, diarrhea, or changes in bowel habits, Ubie's free AI-powered symptom checker can help you evaluate whether your symptoms match Irritable Bowel Syndrome (IBS) and guide your next steps with personalized insights.
While IBS itself is not life-threatening, some symptoms should never be ignored. You should speak to a doctor promptly if you experience:
A doctor can rule out serious conditions and help confirm whether IBS is the most likely explanation.
If IBS symptoms are affecting your quality of life, do not dismiss them—and do not face them alone. A healthcare professional can help guide safe, effective treatment tailored to your needs.
(References)
* Ohlsson B. Sex and Gender Differences in Irritable Bowel Syndrome. J Clin Med. 2023 Aug 24;12(17):5524. doi: 10.3390/jcm12175524. PMID: 37637497; PMCID: PMC10488057.
* Bajaj N, Tarbell S, Madan A, Sharma D, Chey WD, Eswaran S. Sex Differences in Irritable Bowel Syndrome: A Review of Biological and Psychological Factors. J Neurogastroenterol Motil. 2020 Jul 30;26(3):285-299. doi: 10.5056/jnm20021. PMID: 32338600; PMCID: PMC7378771.
* Khan N, Gupta S, Kichloo A, Al-Otaibi F, Khan N, Singh A, Darr U. Sex Differences in Irritable Bowel Syndrome: A Role for Visceral Pain and the Gut Microbiome. Cureus. 2023 Jun 16;15(6):e40502. doi: 10.7759/cureus.40502. PMID: 37454848; PMCID: PMC10352128.
* Mulak A, Tache Y, Million M. Sex and Gender in Irritable Bowel Syndrome: A Narrative Review of Pathophysiology and Clinical Impact. Gastroenterol Clin North Am. 2019 Mar;48(1):141-163. doi: 10.1016/j.gtc.2018.09.006. PMID: 30678850; PMCID: PMC6698628.
* Kim S, Kim K, Kim TW, Jung ES, Choi B, Jo HJ, Lee JE. Sex hormones in irritable bowel syndrome: a review of current knowledge. J Gastroenterol Hepatol. 2022 Feb;37(2):299-307. doi: 10.1111/jgh.15570. Epub 2021 Jul 22. PMID: 34293976.
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