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Published on: 2/19/2026

Internal Fire? Why Your Body Shuts Down & How to Stop Sepsis

Sepsis is a life-threatening internal fire where an infection triggers an out-of-control immune response that leads to widespread inflammation, leaky blood vessels, dangerously low blood pressure, organ failure, and death if not treated quickly, yet early care can be lifesaving. Watch for infection plus fever or very low temperature, rapid heart or breathing, severe pain, clammy skin, confusion, bluish or pale skin, or low urine and seek emergency care; hospital treatment includes urgent antibiotics, IV fluids, oxygen, blood pressure support, and removing the infection source, while prevention centers on early infection care, completing antibiotics, wound care, hand hygiene, and vaccines. There are several factors to consider that can affect your next steps; see below for complete details.

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Explanation

Internal Fire? Why Your Body Shuts Down — and How to Stop Sepsis

When people describe sepsis, they often call it an "internal fire." That's not far from the truth. Sepsis happens when your body's response to an infection becomes extreme and harmful. Instead of fighting off germs in a controlled way, the immune system goes into overdrive. The result? Widespread inflammation that can damage tissues, disrupt blood flow, and cause organs to fail.

Sepsis is a medical emergency. But it's also treatable—especially when caught early. Understanding what it is, why it happens, and what to look for can make a lifesaving difference.


What Is Sepsis?

Sepsis is a life-threatening condition that occurs when the body's response to an infection injures its own tissues and organs.

It can begin with almost any infection, including:

  • Pneumonia (lung infection)
  • Urinary tract infections (UTIs)
  • Skin infections
  • Abdominal infections (like appendicitis)
  • Infected wounds
  • Bloodstream infections

Most infections stay localized and resolve with proper treatment. But sometimes, the immune system releases chemicals into the bloodstream that trigger widespread inflammation. Blood vessels may leak. Blood pressure can drop. Oxygen and nutrients struggle to reach vital organs.

If not treated quickly, sepsis can progress to:

  • Septic shock (dangerously low blood pressure)
  • Organ failure
  • Death

This is why early recognition is so important.


Why Does the Body "Shut Down"?

Think of your immune system as a fire department. Normally, it puts out small fires (infections) efficiently. But in sepsis, the response becomes chaotic—like spraying water everywhere, damaging the building in the process.

Here's what happens inside the body:

  • Widespread inflammation damages blood vessels.
  • Leaky blood vessels cause fluid to move into tissues.
  • Low blood pressure reduces blood flow to organs.
  • Clotting abnormalities block small blood vessels.
  • Organ dysfunction begins (kidneys, lungs, heart, brain).

When organs don't receive enough oxygen-rich blood, they begin to fail. That's the "shutdown" people refer to.


Who Is at Higher Risk for Sepsis?

Anyone can develop sepsis. However, certain groups are at higher risk:

  • Adults over 65
  • Infants under 1 year
  • People with weakened immune systems
  • Individuals with chronic conditions (diabetes, cancer, kidney disease)
  • People recently hospitalized
  • Those with medical devices (catheters, IV lines)
  • People recovering from surgery
  • Individuals with untreated infections

Even healthy people can develop sepsis, especially after a severe infection or injury.


Early Signs and Symptoms of Sepsis

Sepsis symptoms can develop quickly and may initially look like flu or worsening infection.

Common early signs include:

  • Fever or very low body temperature
  • Chills and shivering
  • Rapid heart rate
  • Rapid breathing or shortness of breath
  • Extreme pain or discomfort
  • Clammy or sweaty skin
  • Confusion or disorientation

As sepsis worsens, symptoms may include:

  • Very low blood pressure
  • Decreased urine output
  • Difficulty staying awake
  • Bluish or pale skin
  • Severe weakness

If you notice these symptoms, especially alongside an infection, seek medical care immediately.

If you're experiencing concerning symptoms and want to understand whether they could indicate sepsis, Ubie's free AI-powered Sepsis Symptom Checker can help assess your risk in minutes—so you can make an informed decision about seeking immediate care.


How Is Sepsis Diagnosed?

Doctors diagnose sepsis based on:

  • Symptoms
  • Vital signs (heart rate, blood pressure, breathing rate)
  • Blood tests
  • Urine tests
  • Imaging (X-ray, CT scan)
  • Identification of the infection source

There is no single "sepsis test." It's a clinical diagnosis based on signs of infection combined with signs of organ dysfunction.

Because sepsis can progress rapidly, doctors often begin treatment before every test result is available.


How Is Sepsis Treated?

Sepsis is treated in a hospital, often in an intensive care unit (ICU). Treatment usually includes:

1. Antibiotics

  • Given immediately, often within the first hour of diagnosis.
  • Broad-spectrum antibiotics are used first.
  • Adjusted once the infection source is identified.

2. IV Fluids

  • Help raise blood pressure.
  • Improve circulation to organs.

3. Oxygen Therapy

  • Ensures organs receive adequate oxygen.
  • May require a breathing machine in severe cases.

4. Medications

  • To raise blood pressure if fluids aren't enough.
  • To support heart function.
  • To control blood sugar.

5. Source Control

  • Draining abscesses.
  • Removing infected devices.
  • Surgery if necessary.

The earlier treatment begins, the better the outcome.


Can Sepsis Be Prevented?

Not all cases are preventable, but you can reduce your risk.

Practical Steps:

  • Treat infections early.
  • Complete prescribed antibiotics.
  • Keep wounds clean and covered.
  • Stay up to date on vaccines (flu, pneumonia, COVID-19).
  • Practice good hand hygiene.
  • Manage chronic health conditions carefully.

If you have an infection that suddenly worsens, don't ignore it.


What Happens After Surviving Sepsis?

Many people recover fully, especially with early treatment. However, some experience what's known as post-sepsis syndrome, which may include:

  • Fatigue
  • Brain fog
  • Weakness
  • Sleep problems
  • Anxiety or depression

Recovery can take weeks to months. Follow-up care is important. Physical therapy, mental health support, and ongoing medical supervision may help.


Why Early Action Matters

Sepsis can move fast. What starts as a manageable infection can escalate within hours.

However:

  • Early antibiotics dramatically improve survival.
  • Early fluids reduce organ damage.
  • Early recognition saves lives.

Sepsis is serious—but it is treatable.

The key difference between recovery and severe complications often comes down to time.


When to Seek Immediate Medical Care

Call emergency services or go to the nearest emergency department if you or someone else has:

  • Signs of infection plus
  • Confusion or extreme sleepiness
  • Trouble breathing
  • Very low blood pressure
  • Blue or pale skin
  • Severe pain that feels "not normal"

Do not wait to "see if it gets better."


Final Thoughts: Stay Alert, Not Afraid

Sepsis is not rare. But it is also not inevitable. Most infections do not turn into sepsis.

The goal is awareness—not panic.

If something feels wrong, especially during an infection, listen to your body. Take action quickly by using Ubie's free AI-powered Sepsis Symptom Checker to evaluate your symptoms and get guidance on your next steps. And most importantly, speak to a doctor immediately about anything that could be life threatening or serious.

Prompt medical care saves lives.

Sepsis is an internal fire—but with early recognition and proper treatment, it can be extinguished.

(References)

  • * Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll K, Vincent JL, Angus DC. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016 Feb 23;315(8):801-10. doi: 10.1001/jama.2016.0287. PMID: 26903338.

  • * Chaudhry H, Duggal A, Rosenthal MD, Bander J, Brause P, Pinsky MR. Organ dysfunction in sepsis. Crit Care Med. 2023 Mar 1;51(3):e116-e126. doi: 10.1097/CCM.0000000000005700. Epub 2022 Nov 21. PMID: 36410499.

  • * Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, Levy M, Machado FR, McCarthy M, McIntrye L, Ostermann C, Prescott HC, Schorr S, Simpson S, Sirounis D, Taylor B, Townsend S, van der Poll K, Dellinger RP. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e1143. doi: 10.1097/CCM.0000000000005337. Epub 2021 Sep 30. PMID: 34509763.

  • * Hotchkiss RS, Moldawer LL, Opal SM, Coopersmith CM, Deutschman CS, Levy MM. Sepsis and septic shock. Nat Rev Dis Primers. 2023 May 11;9(1):20. doi: 10.1038/s41572-023-00431-7. PMID: 37169871.

  • * Pugin J, Contou D, de Prost N, Legrand M. Current and future treatments for sepsis: The dawn of host-directed therapy. Intensive Care Med. 2023 Apr;49(4):371-382. doi: 10.1007/s00134-023-07010-z. Epub 2023 Mar 2. PMID: 36862368.

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