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Have a fever
Fatigued
Mood swings (dozing, getting angry too easily, getting confused, and low energy levels)
Have a headache
Becoming listless and unenergetic
Poor feeding
Brain fog
Not seeing your symptoms? No worries!
Sepsis occurs when the immune system has an extreme response to an infection, damaging healthy tissues and organs and leading to poor organ function. It can worsen to septic shock, a severe form of sepsis that is life-threatening.
Your doctor may ask these questions to check for this disease:
Emergency medical treatment in a hospital is necessary. Treatment includes administering antibiotics, anti-inflammatory medication, and fluids directly into the vein in a timely manner. Quick action to control the infection source is also needed. Heart and blood pressure support is necessary for severe cases like septic shock.
Reviewed By:
Saqib Baig, MD, MS (Pulmonology, Critical Care, Internal Medicine)
Dr. Baig graduated from Army Medical College (NUST) Pakistan in 2007. He did his internal medicine training from Baltimore, Maryland, USA during the years 2009-2013. He joined the internal medicine faculty practice at Medical College of Wisconsin in USA for 2 years before pursuing advanced training. He completed his pulmonary disease and critical care medicine fellowship from Rutgers Robert Wood Johnson Medical School from 2015-2018. | | During his fellowship, Dr. Baig completed his master's in health care services management through Rutgers Business School. He currently serves as the medical director of respiratory therapy and pulmonary function lab and the clinical director of the COPD program at the Jane and Leonard Korman Respiratory Institute at Thomas Jefferson University. He holds the Assistant Professor of Medicine rank at Sidney Kimmel Medical College at Thomas Jefferson University. Dr. Baig's interests lie in respiratory physiology, airways disease, and data science.
Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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With a free 3-min Sepsis quiz, powered by Ubie's AI and doctors, find possible causes of your symptoms.
This questionnaire is customized to your situation and symptoms, including the following personal information:
Biological Sex - helps us provide relevant suggestions for male vs. female conditions.
Age - adjusts our guidance based on any age-related health factors.
History - considers past illnesses, surgeries, family history, and lifestyle choices.
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See full list
Q.
Sepsis Signs Women 30-45 Often Miss: Symptoms & Next Steps
A.
Women 30 to 45 often miss early sepsis signs like fever or low temperature, fast heart rate, rapid breathing, extreme fatigue, confusion, severe or unusual pain, much less urination, and pale, blotchy, or blue-tinged skin, especially after UTIs, pneumonia, wounds, childbirth or miscarriage, C-section, IUD insertion, or pelvic surgery. If you have an infection and develop trouble breathing, confusion, severe worsening pain, faintness or very low blood pressure, or blue or gray lips, seek emergency care immediately since early antibiotics and fluids save lives. There are several factors to consider for risks, red flags, and prevention steps like prompt infection care, finishing antibiotics, wound care, vaccines, and managing chronic conditions, so see the complete guidance below.
References:
* pubmed.ncbi.nlm.nih.gov/31897453/
* pubmed.ncbi.nlm.nih.gov/23979450/
* pubmed.ncbi.nlm.nih.gov/34561284/
* pubmed.ncbi.nlm.nih.gov/36341295/
* pubmed.ncbi.nlm.nih.gov/31898517/
Q.
Sepsis in Women 65+: Life-Saving Warning Signs You Must Know
A.
In women 65+, sepsis is a medical emergency; urgent warning signs include sudden confusion or sleepiness, fast breathing or heart rate, fever or feeling very cold, extreme weakness, pale or clammy skin, decreased urination, and any rapid worsening like low blood pressure or severe shortness of breath, often after infections such as UTIs, pneumonia, or skin wounds. There are several factors to consider, and symptoms can be subtle in older women, so see below for the full checklist of signs, common sources, who is most at risk, what doctors do, prevention and recovery tips, and the exact next steps including when to seek emergency care and how a symptom check can help.
References:
* Papi, E., Frangella, E., Perrella, A., Zanza, C., Cazzato, S., Orlando, A., Sgueglia, M., Abenavoli, L., Cestari, L., Piccioni, F., Scarlata, S., & Pirozzolo, G. (2021). Sepsis in the Elderly: A Narrative Review. *Journal of Clinical Medicine*, *10*(14), 3167. DOI: 10.3390/jcm10143167
* Faulstich, M., Kianfar, H., & Schefold, J. C. (2020). Sepsis in Older Adults: A Review of the Current Literature. *Journal of Clinical Medicine*, *9*(10), 3289. DOI: 10.3390/jcm9103289
* Sun, J., Yang, H., Mao, Z., Guo, S., Wang, T., Zhang, S., Li, Y., Jiang, L., & Xi, J. (2021). Clinical features and outcome of sepsis in older adults: A systematic review and meta-analysis. *Aging Clinical and Experimental Research*, *33*(1), 1–13. DOI: 10.1007/s11357-020-00331-5
* Leligdowicz, A., Dupuis, G., St-Louis, E., & St-Pierre, S. (2018). Sex Differences in Clinical Features, Course, and Outcome of Sepsis: A Systematic Review. *Shock*, *50*(6), 614–625. DOI: 10.1097/SHK.0000000000001089
* Wewers, M. D., & Kern, J. (2018). Sex differences in sepsis: current insights. *Infection and Drug Resistance*, *11*, 1545–1553. DOI: 10.2147/IDR.S164741
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Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1Faix JD. Biomarkers of sepsis. Crit Rev Clin Lab Sci. 2013 Jan-Feb;50(1):23-36. doi: 10.3109/10408363.2013.764490. PMID: 23480440; PMCID: PMC3613962.
https://www.tandfonline.com/doi/full/10.3109/10408363.2013.764490Purcarea A, Sovaila S. Sepsis, a 2020 review for the internist. Rom J Intern Med. 2020 Sep 1;58(3):129-137. doi: 10.2478/rjim-2020-0012. PMID: 32396142.
https://www.sciendo.com/article/10.2478/rjim-2020-0012Napolitano LM. Sepsis 2018: Definitions and Guideline Changes. Surg Infect (Larchmt). 2018 Feb/Mar;19(2):117-125. doi: 10.1089/sur.2017.278. PMID: 29447109.
https://www.liebertpub.com/doi/10.1089/sur.2017.278Rello J, Valenzuela-Sánchez F, Ruiz-Rodriguez M, Moyano S. Sepsis: A Review of Advances in Management. Adv Ther. 2017 Nov;34(11):2393-2411. doi: 10.1007/s12325-017-0622-8. Epub 2017 Oct 11. PMID: 29022217; PMCID: PMC5702377.
https://link.springer.com/article/10.1007/s12325-017-0622-8