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Published on: 2/23/2026
There are several factors to consider: while Sjogren’s syndrome can explain persistent dry eyes and mouth with fatigue or joint pain, common alternatives like medications, menopause, diabetes, thyroid problems, or dehydration can also cause body-wide dryness. See below for the complete steps on diagnosis and care, including which blood, eye, and salivary tests to ask about, key complications like dental decay and corneal damage to watch for, and practical next steps such as tracking symptoms, reviewing medications, and scheduling a primary care visit with possible rheumatology referral.
If your eyes burn by midday, your mouth feels sticky no matter how much water you drink, or your skin seems constantly dry, you may be wondering: Is it Sjogren's syndrome?
Occasional dryness is common. But when dryness becomes persistent, uncomfortable, and affects multiple parts of your body, it may signal something more than dehydration or aging.
This guide explains what Sjogren's syndrome is, why it causes dryness, the symptoms to watch for, and what medical steps to take next.
Sjogren's syndrome is a chronic autoimmune disease. That means your immune system mistakenly attacks healthy tissues — specifically the glands that produce moisture.
The condition most often affects:
But it can also affect joints, lungs, nerves, kidneys, and other organs.
There are two main types:
It is more common in women, especially over age 40, but it can affect anyone.
In Sjogren's syndrome, immune cells attack moisture-producing glands. Over time, this reduces your body's ability to make:
Because moisture is essential for protection and comfort, the result is widespread dryness that can affect daily life.
Dryness may involve:
This dryness is not just uncomfortable — it can lead to complications if untreated.
The hallmark symptoms are:
You may experience:
Some people paradoxically experience watery eyes — this can happen because irritation triggers reflex tearing, even though baseline tear production is low.
This can cause:
Saliva protects teeth and gums. Without it, dental problems become more common.
Sjogren's syndrome is systemic, meaning it can affect the whole body. You may also notice:
In more serious cases, organs such as the lungs, kidneys, or nerves can become involved.
While most cases are manageable, untreated systemic involvement can become serious — which is why proper evaluation matters.
Yes. Not all dryness means Sjogren's syndrome.
Other causes include:
This is why medical testing is important. Symptoms alone cannot confirm Sjogren's syndrome.
If you're experiencing persistent dryness and want to understand whether your symptoms align with this condition, Ubie offers a free AI-powered symptom checker specifically for Sjogren Syndrome that can help you assess your situation before seeing a doctor.
There is no single test that confirms Sjogren's syndrome. Diagnosis typically involves a combination of:
Your doctor will ask about:
These may check for:
Not everyone with Sjogren's tests positive for antibodies, so normal labs do not automatically rule it out.
An ophthalmologist may perform:
A lip biopsy checks for immune cell clusters in salivary glands and can help confirm diagnosis when blood tests are unclear.
Sjogren's syndrome is usually slow-moving, but it is not harmless.
Possible complications include:
Most people do not develop severe complications, but early monitoring reduces risk.
There is currently no cure, but treatment focuses on symptom control and preventing complications.
If organs are involved, rheumatologists may prescribe stronger immune-modulating medications.
Treatment is individualized based on symptom severity and organ involvement.
You should schedule a medical evaluation if you have:
Seek urgent medical care if you experience:
While these complications are not common, they should never be ignored.
Always speak to a doctor about symptoms that could be serious or life threatening.
If diagnosed, many people live full, active lives with proper management.
Helpful lifestyle strategies include:
Support from a rheumatologist, dentist, and eye specialist often provides the best long-term care.
If your body always feels dry — especially your eyes and mouth — and it's not improving with simple measures, Sjogren's syndrome may be worth investigating.
Not all dryness is autoimmune disease. But persistent, multi-area dryness combined with fatigue or joint pain should not be dismissed.
Next steps:
Early evaluation brings clarity. Early treatment prevents complications.
And most importantly, if you are worried that something serious could be happening, do not wait — speak to a doctor promptly.
Your body's dryness may be manageable. The key is understanding the cause and taking informed next steps.
(References)
* Brito-Zerón P, Baldini C, Gottenberg JE, et al. Update on the classification of Sjögren's syndrome. Rheumatology (Oxford). 2021 May 1;60(5):2131-2140. doi: 10.1093/rheumatology/keaa799. PMID: 33454659.
* Baer AN. Clinical manifestations of Sjögren's syndrome: More than just dry eyes and mouth. F1000Res. 2019 Jul 24;8:F1000 Faculty Rev-1249. doi: 10.12688/f1000research.19641.1. PMID: 31440337.
* Ramos-Casals M, Brito-Zerón P, Bombardieri S, et al. Primary Sjögren syndrome: New clinical and therapeutic insights. Nat Rev Rheumatol. 2020 Aug;16(8):417-431. doi: 10.1038/s41584-020-0445-5. PMID: 32601449.
* Mariette X, Criswell LA. Sjögren's syndrome. Lancet. 2017 Mar 4;389(10072):917-931. doi: 10.1016/S0140-6736(16)30952-7. PMID: 28271871.
* Shiboski CH, Shiboski SC, Seror R, et al. American College of Rheumatology/European League Against Rheumatism Classification Criteria for Primary Sjögren's Syndrome: A Consensus and Data-Driven Approach From the Sjögren's International Collaborative Clinical Alliance. Arthritis Rheumatol. 2017 Jan;69(1):35-42. doi: 10.1002/art.39460. PMID: 27912442.
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