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Published on: 5/6/2025

What Could a Lump in the Left Hypochondriac Region Mean?

A lump in the left hypochondriac region may represent a tumor or tumor-like lesion. Possibilities include lipomas which are benign fat deposits, gastrointestinal stromal tumors which are lesions arising in the abdominal wall, or even liver masses like a pedunculated giant hemangioma. Even severe constipation causing stool back up may cause a sensation of a lump in this area.

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Explanation

A palpable lump in the left hypochondriac region—the area in the left upper quadrant of the abdomen—warrants evaluation because it can be caused by a variety of conditions. For example, although relatively rare, a gastrointestinal stromal tumor (GIST) can present as a palpable mass in this region. Additionally, tumors or tumor-like lesions in the abdominal wall, which could be detected during imaging studies such as CT or MRI, could present as a lump. Benign tumors of the abdomen, such as lipomas, are common causes. Another possibility is a liver lesion; in one reported case, a pedunculated giant hemangioma (a benign tumor of blood vessels) presented with left hypochondrial pain and could be felt as a mass. If you discover such a lump, further evaluation—including imaging studies and possibly a biopsy—is essential to determine the exact cause and guide appropriate treatment.

(References)

  • Bhambare MR, Pandya JS, Waghmare SB, Shetty TS. Gastrointestinal stromal tumour presenting as palpable abdominal mass: A rare entity. World J Gastrointest Surg. 2015 Jun 27;7(6):98-101. doi: 10.4240/wjgs.v7.i6.98. PMID: 26131332; PMCID: PMC4478562.

  • Li M, Zhang L, Xu XJ, Shi Z, Zhao XM. CT and MRI features of tumors and tumor-like lesions in the abdominal wall. Quant Imaging Med Surg. 2019 Nov;9(11):1820-1839. doi: 10.21037/qims.2019.09.03. PMID: 31867236; PMCID: PMC6902146.

  • Kouki S, Helal I, Ben Lassoued M. Unusual cause of a left hypochondria pain: pedunculated giant haemangioma of the liver. BMJ Case Rep. 2019 Aug 26;12(8):e224349. doi: 10.1136/bcr-2018-224349. PMID: 31451450; PMCID: PMC6721412.

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