Can Lyme disease cause chronic fatigue and vertigo?

Reviewed by Yoshinori Abe, MD

Internal Medicine

Lyme disease is a tick-borne illness that can trigger a wide range of symptoms, including chronic fatigue and vertigo. When the infection spreads to the brain and nervous system—a condition known as neurological Lyme disease or neuroborreliosis—these symptoms often become more pronounced and persistent. Fatigue may feel debilitating, while vertigo can cause dizziness, balance issues, and disorientation.

Because Lyme symptoms overlap with many other conditions, identifying the cause early is critical for effective treatment. If you're experiencing unexplained fatigue, dizziness, or other concerning symptoms, taking a free, instant, online symptom check can help you better understand what may be behind them and guide your next steps toward the right care.

Reviewed for medical accuracy: 07/15/2026

Important Next Steps

Discover if Lyme disease fits your fatigue Learn if your vertigo needs care today Find likely causes of chronic fatigue See OTC relief for fatigue and dizziness Find a doctor for Lyme disease Discover valid home remedies for vertigo Understand whether persistent symptoms need urgent evaluation

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Explanation

Lyme disease is an infection that can sometimes affect the brain, leading to symptoms such as chronic fatigue and vertigo. When Lyme disease impacts the brain, it is known as Lyme encephalitis. This condition can cause a variety of symptoms, including tiredness that doesn't go away and feeling dizzy or off-balance, which is known as vertigo.

Chronic Fatigue: This means feeling very tired all the time, even after resting. It can make it hard to do everyday things.
Vertigo: This is when you feel like you're spinning or things around you are moving when they're not. It can make you feel dizzy and unsteady.

If you're experiencing persistent fatigue, dizziness, or other concerning symptoms, you can use Ubie's free AI symptom checker to help identify potential causes and determine if you should seek medical care. Understanding these symptoms can help in recognizing and managing the condition effectively.

(References)

Verma V, Roman M, Shah D, Zaretskaya M, & Yassin MH. (2014). A case of chronic progressive lyme encephalitis as .... Infectious disease reports, 25568755.
Novak P. (2020). Post COVID-19 syndrome associated with orthostatic .... eNeurologicalSci, 32984564.

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