Published on: 7/22/2025
What are the symptoms of Post-Treatment Lyme Disease Syndrome (PTLDS)?
Post-Treatment Lyme Disease Syndrome (PTLDS) can cause tiredness, joint and muscle pain, and trouble thinking clearly, even after Lyme disease treatment.
Explanation
Post-Treatment Lyme Disease Syndrome (PTLDS) occurs after someone has been treated for Lyme disease, but still experiences symptoms. These symptoms can last for months or even years.
Common Symptoms of PTLDS Include:
- Fatigue: People often feel very tired and have low energy levels.
- Pain: There can be ongoing aches in muscles and joints.
- Cognitive Issues: Some people have trouble thinking clearly, concentrating, or remembering things.
These symptoms can vary in how severe they are and can affect daily life. It is important to talk to a healthcare provider if you think you have PTLDS, so they can help manage these symptoms. For mental health support, visit 988lifeline.org.
(References)
- Wester KE, Nwokeabia BC, Hassan R, Dunphy T, Osondu M, Wonders C, & Khaja M. (2024). Exploring the Mechanisms of Post-treatment Lyme Disease .... Cureus, 39161484.
- Aucott JN. (2015). Posttreatment Lyme disease syndrome. Infectious disease clinics of North America, 25999226.
- Bai NA, & Richardson CS. (2023). Posttreatment Lyme disease syndrome and myalgic .... Chronic diseases and translational medicine, 37711861.
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