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Published on: 11/26/2025
Are there medications that should not be combined with sleep aids due to risk of confusion or wandering?
Some medications, when combined with sleep aids, can increase the risk of confusion or wandering, such as valproic acid with sleep aids or methamphetamine with zolpidem.
Questions about combining sleep aids with other meds?
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Certain medications should not be mixed with sleep aids because they can cause confusion or even wandering. For example, valproic acid, when combined with sleep aids, might lead to sleepwalking or somnambulism.
Additionally, combining methamphetamine with zolpidem, a common sleep aid, can also cause unusual behaviors. These interactions can make a person act confused or do things they might not remember later.
Here are some key points to consider:
- Valproic Acid and Sleep Aids: This combination might lead to sleepwalking, where a person might get up and walk around while still asleep.
- Methamphetamine and Zolpidem: This mix can cause confusion and strange behaviors.
It is essential to be careful when taking sleep aids with other drugs. Always talk to a doctor or pharmacist to ensure that your medications are safe to take together. If you or someone you know is experiencing mental health concerns, you can visit 988lifeline.org for support.
(References)
- Dokkedal-Silva V, Galduróz JCF, Tufik S, & Andersen ML. (2020). Combined cocaine and clonazepam administration .... Pharmacology, biochemistry, and behavior, 32795565.
- Sattar SP, Ramaswamy S, Bhatia SC, & Petty F. (2003). Somnambulism due to probable interaction of valproic acid .... The Annals of pharmacotherapy, 14519043.
- Hart CL, Haney M, Nasser J, & Foltin RW. (2005). Combined effects of methamphetamine and zolpidem on .... Pharmacology, biochemistry, and behavior, 15936062.
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