Can medications cause or worsen sleepwalking?

Yes, certain medications can cause or worsen sleepwalking. The most common culprits include:

• Sedative-hypnotic sleep aids (such as zolpidem and other "Z-drugs")
• Antipsychotic medications (such as quetiapine and olanzapine)
• Benzodiazepines used for anxiety or insomnia
• Some antidepressants, particularly SSRIs
• Certain beta-blockers used for blood pressure

Sleepwalking triggered by medication typically occurs during the first few hours of sleep and may involve walking, talking, or performing complex activities with no memory of the event. If you suspect a medication is causing sleepwalking episodes, do not stop taking it abruptly—speak with your healthcare provider first.

Because sleepwalking can also stem from stress, sleep deprivation, or underlying sleep disorders, identifying the true cause matters. Take a free, instant, online symptom check to better understand what may be driving your symptoms and get personalized guidance on the right next steps.

Reviewed for medical accuracy: 07/20/2026